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Atomistry » Manganese » PDB 2a7a-2axt » 2ano » |
Manganese in PDB 2ano: Crystal Structure of E.Coli Dihydrofolate Reductase in Complex with Nadph and the Inhibitor Ms-SH08-17Enzymatic activity of Crystal Structure of E.Coli Dihydrofolate Reductase in Complex with Nadph and the Inhibitor Ms-SH08-17
All present enzymatic activity of Crystal Structure of E.Coli Dihydrofolate Reductase in Complex with Nadph and the Inhibitor Ms-SH08-17:
1.5.1.3; Protein crystallography data
The structure of Crystal Structure of E.Coli Dihydrofolate Reductase in Complex with Nadph and the Inhibitor Ms-SH08-17, PDB code: 2ano
was solved by
R.L.Summerfield,
D.M.Daigle,
S.Mayer,
S.G.Jackson,
M.Organ,
D.W.Hughes,
E.D.Brown,
M.S.Junop,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2ano:
The structure of Crystal Structure of E.Coli Dihydrofolate Reductase in Complex with Nadph and the Inhibitor Ms-SH08-17 also contains other interesting chemical elements:
Manganese Binding Sites:
The binding sites of Manganese atom in the Crystal Structure of E.Coli Dihydrofolate Reductase in Complex with Nadph and the Inhibitor Ms-SH08-17
(pdb code 2ano). This binding sites where shown within
5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Crystal Structure of E.Coli Dihydrofolate Reductase in Complex with Nadph and the Inhibitor Ms-SH08-17, PDB code: 2ano: Manganese binding site 1 out of 1 in 2anoGo back to Manganese Binding Sites List in 2ano
Manganese binding site 1 out
of 1 in the Crystal Structure of E.Coli Dihydrofolate Reductase in Complex with Nadph and the Inhibitor Ms-SH08-17
Mono view Stereo pair view
Reference:
R.L.Summerfield,
D.M.Daigle,
S.Mayer,
D.Mallik,
D.W.Hughes,
S.G.Jackson,
M.Sulek,
M.G.Organ,
E.D.Brown,
M.S.Junop.
A 2.13 A Structure of E. Coli Dihydrofolate Reductase Bound to A Novel Competitive Inhibitor Reveals A New Binding Surface Involving the M20 Loop Region J.Med.Chem. V. 49 6977 2006.
Page generated: Tue Dec 15 03:59:26 2020
ISSN: ISSN 0022-2623 PubMed: 17125251 DOI: 10.1021/JM060570V |
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