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Manganese in PDB 9cal: Human TOP3B-TDRD3 Core Complex in Post-Cleavage State with Ssdna 5'- Acagatatt-3

Enzymatic activity of Human TOP3B-TDRD3 Core Complex in Post-Cleavage State with Ssdna 5'- Acagatatt-3

All present enzymatic activity of Human TOP3B-TDRD3 Core Complex in Post-Cleavage State with Ssdna 5'- Acagatatt-3:
5.6.2.1;

Manganese Binding Sites:

The binding sites of Manganese atom in the Human TOP3B-TDRD3 Core Complex in Post-Cleavage State with Ssdna 5'- Acagatatt-3 (pdb code 9cal). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Human TOP3B-TDRD3 Core Complex in Post-Cleavage State with Ssdna 5'- Acagatatt-3, PDB code: 9cal:

Manganese binding site 1 out of 1 in 9cal

Go back to Manganese Binding Sites List in 9cal
Manganese binding site 1 out of 1 in the Human TOP3B-TDRD3 Core Complex in Post-Cleavage State with Ssdna 5'- Acagatatt-3


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Human TOP3B-TDRD3 Core Complex in Post-Cleavage State with Ssdna 5'- Acagatatt-3 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mn701

b:83.8
occ:1.00
OD2 A:ASP117 2.1 74.2 1.0
OD2 A:ASP119 2.2 76.2 1.0
CG A:ASP117 3.2 74.2 1.0
CG A:ASP119 3.3 76.2 1.0
OD1 A:ASP119 3.7 76.2 1.0
OD1 A:ASP117 3.8 74.2 1.0
CB A:ASP117 4.2 74.2 1.0
CB A:ASP119 4.5 76.2 1.0
OE1 A:GLU9 5.0 70.5 1.0

Reference:

X.Yang, X.Chen, W.Yang, Y.Pommier. Structural Insights Into Human Topoisomerase 3 Beta Dna and Rna Catalysis and Nucleic Acid Gate Dynamics. Nat Commun V. 16 834 2025.
ISSN: ESSN 2041-1723
PubMed: 39828754
DOI: 10.1038/S41467-025-55959-Y
Page generated: Sun Feb 9 08:28:35 2025

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