Manganese in PDB 7vjv: Human Alkb Homolog ALKBH6 in Complex with Alpha-Katoglutarate and Mn

The structure of Human Alkb Homolog ALKBH6 in Complex with Alpha-Katoglutarate and Mn, PDB code: 7vjv was solved by L.Ma, Z.Chen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	26.42 / 1.75
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	46.118, 64.407, 88.416, 90, 90, 90
R / Rfree (%)	19 / 20.7

The binding sites of Manganese atom in the Human Alkb Homolog ALKBH6 in Complex with Alpha-Katoglutarate and Mn (pdb code 7vjv). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Human Alkb Homolog ALKBH6 in Complex with Alpha-Katoglutarate and Mn, PDB code: 7vjv:

Manganese binding site 1 out of 1 in the Human Alkb Homolog ALKBH6 in Complex with Alpha-Katoglutarate and Mn


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Human Alkb Homolog ALKBH6 in Complex with Alpha-Katoglutarate and Mn within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn301 b:12.4 occ:1.00 O5 A:AKG302 2.1 16.9 1.0 NE2 A:HIS182 2.1 12.9 1.0 OD2 A:ASP116 2.1 15.2 1.0 NE2 A:HIS114 2.1 16.5 1.0 O1 A:AKG302 2.1 17.2 1.0 O A:HOH402 2.2 15.8 1.0 C2 A:AKG302 2.8 17.5 1.0 C1 A:AKG302 2.8 18.2 1.0 CE1 A:HIS114 3.0 17.0 1.0 CE1 A:HIS182 3.1 12.3 1.0 CD2 A:HIS182 3.1 13.7 1.0 CG A:ASP116 3.1 16.3 1.0 CD2 A:HIS114 3.1 16.8 1.0 OD1 A:ASP116 3.3 17.9 1.0 O A:HOH482 3.7 23.8 1.0 O2 A:AKG302 4.0 19.5 1.0 O A:HOH414 4.1 23.6 1.0 ND1 A:HIS114 4.1 17.4 1.0 ND1 A:HIS182 4.2 13.0 1.0 C3 A:AKG302 4.2 16.4 1.0 CG A:HIS182 4.2 13.1 1.0 CG A:HIS114 4.2 16.1 1.0 CB A:ASP116 4.5 16.7 1.0 C4 A:AKG302 4.7 17.7 1.0 CA A:ASP116 4.9 16.0 1.0 NH2 A:ARG224 4.9 18.9 1.0

L.Ma, H.Lu, Z.Tian, M.Yang, J.Ma, G.Shang, Y.Liu, M.Xie, G.Wang, W.Wu, Z.Zhang, S.Dai, Z.Chen. Structural Insights Into the Interactions and Epigenetic Functions of Human Nucleic Acid Repair Protein ALKBH6. J.Biol.Chem. V. 298 01671 2022.
ISSN: ESSN 1083-351X
PubMed: 35120926
DOI: 10.1016/J.JBC.2022.101671