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Atomistry » Manganese » PDB 6q9p-6qv8 » 6qgv | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Manganese » PDB 6q9p-6qv8 » 6qgv » |
Manganese in PDB 6qgv: Hif Prolyl Hydroxylase 2 (PHD2/ EGLN1) in Complex with A Spiro[4.5]Decanone Inhibitor (Jphm-2-167)Enzymatic activity of Hif Prolyl Hydroxylase 2 (PHD2/ EGLN1) in Complex with A Spiro[4.5]Decanone Inhibitor (Jphm-2-167)
All present enzymatic activity of Hif Prolyl Hydroxylase 2 (PHD2/ EGLN1) in Complex with A Spiro[4.5]Decanone Inhibitor (Jphm-2-167):
1.14.11.29; Protein crystallography data
The structure of Hif Prolyl Hydroxylase 2 (PHD2/ EGLN1) in Complex with A Spiro[4.5]Decanone Inhibitor (Jphm-2-167), PDB code: 6qgv
was solved by
R.Chowdhury,
J.P.Holt-Martyn,
M.Z.Rahman,
C.J.Schofield,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Manganese Binding Sites:
The binding sites of Manganese atom in the Hif Prolyl Hydroxylase 2 (PHD2/ EGLN1) in Complex with A Spiro[4.5]Decanone Inhibitor (Jphm-2-167)
(pdb code 6qgv). This binding sites where shown within
5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Hif Prolyl Hydroxylase 2 (PHD2/ EGLN1) in Complex with A Spiro[4.5]Decanone Inhibitor (Jphm-2-167), PDB code: 6qgv: Manganese binding site 1 out of 1 in 6qgvGo back to![]() ![]()
Manganese binding site 1 out
of 1 in the Hif Prolyl Hydroxylase 2 (PHD2/ EGLN1) in Complex with A Spiro[4.5]Decanone Inhibitor (Jphm-2-167)
![]() Mono view ![]() Stereo pair view
Reference:
J.P.Holt-Martyn,
R.Chowdhury,
M.Z.Rahman,
A.Tumber,
K.Lippl,
W.Figg,
M.A.Mcdonough,
C.J.Schofield.
Molecular and Cellular Mechanisms of Hif Prolyl Hydroxylase Inhibitors in Clinical Trials To Be Published.
Page generated: Sat Aug 16 21:20:49 2025
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