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Manganese in PDB 5e4n: 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis with D-Tyrosine Bound in the Tyrosine and Phenylalanine Binding Sites
Enzymatic activity of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis with D-Tyrosine Bound in the Tyrosine and Phenylalanine Binding Sites
All present enzymatic activity of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis with D-Tyrosine Bound in the Tyrosine and Phenylalanine Binding Sites:
2.5.1.54;
2.5.1.54;
Protein crystallography data
The structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis with D-Tyrosine Bound in the Tyrosine and Phenylalanine Binding Sites, PDB code: 5e4n
was solved by
S.Reichau,
W.Jiao,
E.J.Parker,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 47.37 / 2.05 |
| Space group | P 32 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 205.739, 205.739, 66.644, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 19.9 / 22.9 |
Other elements in 5e4n:
The structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis with D-Tyrosine Bound in the Tyrosine and Phenylalanine Binding Sites also contains other interesting chemical elements:
| Chlorine | (Cl) | 4 atoms |
Manganese Binding Sites:
The binding sites of Manganese atom in the 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis with D-Tyrosine Bound in the Tyrosine and Phenylalanine Binding Sites
(pdb code 5e4n). This binding sites where shown within
5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis with D-Tyrosine Bound in the Tyrosine and Phenylalanine Binding Sites, PDB code: 5e4n:
Jump to Manganese binding site number: 1; 2;
In total 2 binding sites of Manganese where determined in the 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis with D-Tyrosine Bound in the Tyrosine and Phenylalanine Binding Sites, PDB code: 5e4n:
Jump to Manganese binding site number: 1; 2;
Manganese binding site 1 out of 2 in 5e4n
Go back to
Manganese Binding Sites List in 5e4n
Manganese binding site 1 out
of 2 in the 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis with D-Tyrosine Bound in the Tyrosine and Phenylalanine Binding Sites
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 1 of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis with D-Tyrosine Bound in the Tyrosine and Phenylalanine Binding Sites within 5.0Å range:
|
Manganese binding site 2 out of 2 in 5e4n
Go back to
Manganese Binding Sites List in 5e4n
Manganese binding site 2 out
of 2 in the 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis with D-Tyrosine Bound in the Tyrosine and Phenylalanine Binding Sites
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 2 of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase From Mycobacterium Tuberculosis with D-Tyrosine Bound in the Tyrosine and Phenylalanine Binding Sites within 5.0Å range:
|
Reference:
S.Reichau,
N.J.Blackmore,
W.Jiao,
E.J.Parker.
Probing the Sophisticated Synergistic Allosteric Regulation of Aromatic Amino Acid Biosynthesis in Mycobacterium Tuberculosis Using -Amino Acids. Plos One V. 11 52723 2016.
ISSN: ESSN 1932-6203
PubMed: 27128682
DOI: 10.1371/JOURNAL.PONE.0152723
Page generated: Sat Oct 5 23:59:14 2024
ISSN: ESSN 1932-6203
PubMed: 27128682
DOI: 10.1371/JOURNAL.PONE.0152723
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