Manganese in PDB 4nih: Crystal Structure of Alkb E136L Mutant Protein with Cofactors Bound to Dsdna Containing M6A/A

Enzymatic activity of Crystal Structure of Alkb E136L Mutant Protein with Cofactors Bound to Dsdna Containing M6A/A

All present enzymatic activity of Crystal Structure of Alkb E136L Mutant Protein with Cofactors Bound to Dsdna Containing M6A/A:
1.14.11.33;

Protein crystallography data

The structure of Crystal Structure of Alkb E136L Mutant Protein with Cofactors Bound to Dsdna Containing M6A/A, PDB code: 4nih was solved by C.Q.Yi, C.X.Zhu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

*Resolution Low / High (Å)*	27.24 / 1.37
*Space group*	P 1 2₁ 1
*Cell size a, b, c (Å), α, β, γ (°)*	41.072, 76.369, 53.178, 90.00, 108.98, 90.00
*R / R_free (%)*	15.9 / 18

Manganese Binding Sites:

The binding sites of Manganese atom in the Crystal Structure of Alkb E136L Mutant Protein with Cofactors Bound to Dsdna Containing M6A/A (pdb code 4nih). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Crystal Structure of Alkb E136L Mutant Protein with Cofactors Bound to Dsdna Containing M6A/A, PDB code: 4nih:

Manganese binding site 1 out of 1 in 4nih

Go back to

Manganese Binding Sites List in 4nih

Manganese binding site 1 out of 1 in the Crystal Structure of Alkb E136L Mutant Protein with Cofactors Bound to Dsdna Containing M6A/A

Mono view

Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Crystal Structure of Alkb E136L Mutant Protein with Cofactors Bound to Dsdna Containing M6A/A within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:Mn301 b:11.0 occ:1.00	OD1	A:ASP133	2.1	12.3	1.0
	O1	A:AKG302	2.2	13.3	1.0
	NE2	A:HIS187	2.2	10.9	1.0
	NE2	A:HIS131	2.3	11.1	1.0
	O5	A:AKG302	2.3	12.8	1.0
	O	A:HOH411	2.3	13.0	1.0
	C1	A:AKG302	3.0	14.5	1.0
	C2	A:AKG302	3.0	12.8	1.0
	CG	A:ASP133	3.1	13.0	1.0
	CE1	A:HIS187	3.1	11.1	1.0
	CD2	A:HIS187	3.2	11.0	1.0
	CE1	A:HIS131	3.2	11.3	1.0
	CD2	A:HIS131	3.2	10.9	1.0
	OD2	A:ASP133	3.4	13.6	1.0
	O	A:HOH402	3.9	11.8	1.0
	O	A:HOH416	4.2	16.1	1.0
	O2	A:AKG302	4.2	17.1	1.0
	ND1	A:HIS187	4.2	11.3	1.0
	N1	B:6MA8	4.3	11.1	1.0
	ND1	A:HIS131	4.3	11.4	1.0
	CG	A:HIS187	4.3	11.3	1.0
	CG	A:HIS131	4.3	11.2	1.0
	C2	B:6MA8	4.4	11.0	1.0
	CB	A:ASP133	4.4	13.3	1.0
	C3	A:AKG302	4.5	12.7	1.0
	CZ2	A:TRP178	4.7	14.2	1.0
	C6	B:6MA8	4.7	11.4	1.0
	N	A:ASP133	4.8	13.4	1.0
	N3	B:6MA8	4.9	11.0	1.0

Reference:

C.Zhu, C.Yi. Switching Demethylation Activities Between Alkb Family Rna/Dna Demethylases Through Exchange of Active-Site Residues. Angew.Chem.Int.Ed.Engl. V. 53 3659 2014.
ISSN: ISSN 1433-7851
PubMed: 24596302
DOI: 10.1002/ANIE.201310050

Page generated: Sat Oct 5 20:33:14 2024

Last articles

Fe in 7QHF
Fe in 7QCO
Fe in 7QHM
Fe in 7QBV
Fe in 7QH2
Fe in 7QGT
Fe in 7QBU
Fe in 7Q4W
Fe in 7Q4V
Fe in 7QBT

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy