Atomistry » Manganese » PDB 2jck-2nym » 2jd2
Atomistry »
  Manganese »
    PDB 2jck-2nym »
      2jd2 »

Manganese in PDB 2jd2: X-Ray Structure of 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase, Dxr, RV2870C, From Mycobacterium Tuberculosis, in Complex with Manganese

Enzymatic activity of X-Ray Structure of 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase, Dxr, RV2870C, From Mycobacterium Tuberculosis, in Complex with Manganese

All present enzymatic activity of X-Ray Structure of 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase, Dxr, RV2870C, From Mycobacterium Tuberculosis, in Complex with Manganese:
1.1.1.267;

Protein crystallography data

The structure of X-Ray Structure of 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase, Dxr, RV2870C, From Mycobacterium Tuberculosis, in Complex with Manganese, PDB code: 2jd2 was solved by L.M.Henriksson, T.Unge, T.A.Jones, S.L.Mowbray, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 35.00 / 2.15
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 67.589, 64.812, 85.961, 90.00, 101.89, 90.00
R / Rfree (%) 17.6 / 22.5

Manganese Binding Sites:

The binding sites of Manganese atom in the X-Ray Structure of 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase, Dxr, RV2870C, From Mycobacterium Tuberculosis, in Complex with Manganese (pdb code 2jd2). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the X-Ray Structure of 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase, Dxr, RV2870C, From Mycobacterium Tuberculosis, in Complex with Manganese, PDB code: 2jd2:
Jump to Manganese binding site number: 1; 2;

Manganese binding site 1 out of 2 in 2jd2

Go back to Manganese Binding Sites List in 2jd2
Manganese binding site 1 out of 2 in the X-Ray Structure of 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase, Dxr, RV2870C, From Mycobacterium Tuberculosis, in Complex with Manganese


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of X-Ray Structure of 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase, Dxr, RV2870C, From Mycobacterium Tuberculosis, in Complex with Manganese within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mn1390

b:29.3
occ:1.00
 OD1 A:ASP151 2.2 24.4 1.0
OE1 A:GLU222 2.2 23.1 1.0
OE1 A:GLU153 2.2 24.4 1.0
O A:HOH2158 2.2 25.1 1.0
O A:HOH2159 2.6 39.6 1.0
O A:HOH2160 2.6 29.6 1.0
CD A:GLU153 3.1 20.5 1.0
CG A:ASP151 3.2 22.3 1.0
CD A:GLU222 3.3 18.3 1.0
OE2 A:GLU153 3.3 22.9 1.0
OD2 A:ASP151 3.7 25.4 1.0
OE2 A:GLU222 3.7 17.3 1.0
OG A:SER152 3.9 20.3 1.0
ND2 A:ASN218 3.9 16.0 1.0
NZ A:LYS128 4.2 26.0 1.0
N A:SER152 4.4 16.4 1.0
CG A:GLU153 4.4 17.9 1.0
CG A:GLU222 4.5 15.2 1.0
CB A:ASP151 4.5 18.9 1.0
N A:GLU153 4.6 15.5 1.0
NZ A:LYS219 4.7 13.4 1.0
CB A:GLU153 4.8 15.2 1.0
O4 A:SO41391 4.9 23.9 1.0
CB A:SER152 4.9 16.4 1.0
CA A:ASP151 4.9 18.0 1.0
CG A:ASN218 4.9 14.8 1.0
C A:ASP151 5.0 17.3 1.0

Manganese binding site 2 out of 2 in 2jd2

Go back to Manganese Binding Sites List in 2jd2
Manganese binding site 2 out of 2 in the X-Ray Structure of 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase, Dxr, RV2870C, From Mycobacterium Tuberculosis, in Complex with Manganese


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of X-Ray Structure of 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase, Dxr, RV2870C, From Mycobacterium Tuberculosis, in Complex with Manganese within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mn1390

b:15.3
occ:1.00
 OD2 B:ASP151 2.2 14.7 1.0
OE1 B:GLU222 2.2 10.7 1.0
OE1 B:GLU153 2.2 14.9 1.0
O B:HOH2221 2.2 17.5 1.0
O B:HOH2223 2.3 15.0 1.0
O B:HOH2222 2.3 10.8 1.0
CG B:ASP151 3.1 13.9 1.0
CD B:GLU153 3.1 14.6 1.0
CD B:GLU222 3.3 9.9 1.0
OD1 B:ASP151 3.3 16.2 1.0
OE2 B:GLU153 3.4 14.9 1.0
O B:HOH2132 3.7 15.0 1.0
OE2 B:GLU222 3.7 11.2 1.0
O B:HOH2091 4.0 20.5 1.0
ND2 B:ASN218 4.0 11.1 1.0
OG B:SER152 4.1 13.1 1.0
CG B:GLU153 4.5 10.1 1.0
CB B:ASP151 4.5 11.7 1.0
CG B:GLU222 4.5 9.0 1.0
N B:GLU153 4.7 8.4 1.0
NZ B:LYS219 4.7 8.0 1.0
N B:SER152 4.7 9.1 1.0
O4 B:SO41391 4.7 15.6 1.0
CB B:GLU153 4.8 8.7 1.0

Reference:

L.M.Henriksson, T.Unge, J.Carlsson, J.Aqvist, S.L.Mowbray, T.A.Jones. Structures of Mycobacterium Tuberculosis 1-Deoxy-D- Xylulose-5-Phosphate Reductoisomerase Provide New Insights Into Catalysis. J.Biol.Chem. V. 282 19905 2007.
ISSN: ISSN 0021-9258
PubMed: 17491006
DOI: 10.1074/JBC.M701935200
Page generated: Sat Oct 5 14:33:52 2024

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy