Atomistry » Manganese » PDB 2ayl-2ce4 » 2bev
Atomistry »
  Manganese »
    PDB 2ayl-2ce4 »
      2bev »

Manganese in PDB 2bev: Reactivity Modulation of Human Branched-Chain Alpha-Ketoacid Dehydrogenase By An Internal Molecular Switch

Enzymatic activity of Reactivity Modulation of Human Branched-Chain Alpha-Ketoacid Dehydrogenase By An Internal Molecular Switch

All present enzymatic activity of Reactivity Modulation of Human Branched-Chain Alpha-Ketoacid Dehydrogenase By An Internal Molecular Switch:
1.2.4.4;

Protein crystallography data

The structure of Reactivity Modulation of Human Branched-Chain Alpha-Ketoacid Dehydrogenase By An Internal Molecular Switch, PDB code: 2bev was solved by M.Machius, R.M.Wynn, J.L.Chuang, D.R.Tomchick, C.A.Brautigam, D.T.Chuang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 1.80
Space group P 31 2 1
Cell size a, b, c (Å), α, β, γ (°) 144.473, 144.473, 69.480, 90.00, 90.00, 120.00
R / Rfree (%) 13.8 / 17

Other elements in 2bev:

The structure of Reactivity Modulation of Human Branched-Chain Alpha-Ketoacid Dehydrogenase By An Internal Molecular Switch also contains other interesting chemical elements:

Potassium (K) 2 atoms
Chlorine (Cl) 2 atoms

Manganese Binding Sites:

The binding sites of Manganese atom in the Reactivity Modulation of Human Branched-Chain Alpha-Ketoacid Dehydrogenase By An Internal Molecular Switch (pdb code 2bev). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Reactivity Modulation of Human Branched-Chain Alpha-Ketoacid Dehydrogenase By An Internal Molecular Switch, PDB code: 2bev:

Manganese binding site 1 out of 1 in 2bev

Go back to Manganese Binding Sites List in 2bev
Manganese binding site 1 out of 1 in the Reactivity Modulation of Human Branched-Chain Alpha-Ketoacid Dehydrogenase By An Internal Molecular Switch


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Reactivity Modulation of Human Branched-Chain Alpha-Ketoacid Dehydrogenase By An Internal Molecular Switch within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mn1403

b:6.2
occ:1.00
 O3B A:THY601 2.1 2.0 1.0
O2A A:THY601 2.1 2.0 1.0
OE1 A:GLU193 2.2 8.3 1.0
O A:TYR224 2.2 5.9 1.0
OD1 A:ASN222 2.2 8.0 1.0
O A:HOH2381 2.4 7.7 1.0
OE2 A:GLU193 2.7 8.5 1.0
CD A:GLU193 2.8 9.8 1.0
CG A:ASN222 3.2 10.7 1.0
C A:TYR224 3.3 6.5 1.0
PA A:THY601 3.3 2.0 1.0
PB A:THY601 3.3 2.4 1.0
O3A A:THY601 3.5 2.2 1.0
ND2 A:ASN222 3.5 11.8 1.0
N A:ALA225 4.0 6.4 1.0
N A:TYR224 4.0 7.8 1.0
O5G A:THY601 4.1 2.0 1.0
O1B A:THY601 4.1 2.0 1.0
CA A:ALA225 4.1 5.0 1.0
N A:GLU193 4.2 4.3 1.0
CA A:TYR224 4.3 7.9 1.0
CG A:GLU193 4.3 4.4 1.0
N A:ASN222 4.3 7.4 1.0
O A:HOH2272 4.4 10.6 1.0
CB A:ASN222 4.5 8.0 1.0
N A:GLY194 4.5 6.9 1.0
O1A A:THY601 4.5 2.0 1.0
CB A:ALA225 4.6 3.0 1.0
O A:ARG220 4.6 8.4 1.0
O2B A:THY601 4.7 4.1 1.0
N A:GLY223 4.7 9.8 1.0
C A:ASN222 4.7 9.7 1.0
CA A:ASN222 4.7 8.9 1.0
CA A:GLY192 4.9 5.1 1.0
CB A:GLU193 5.0 4.1 1.0
C A:GLY192 5.0 5.7 1.0
CA A:GLU193 5.0 5.6 1.0

Reference:

M.Machius, R.M.Wynn, J.L.Chuang, J.Li, R.Kluger, D.Yu, D.R.Tomchick, C.A.Brautigam, D.T.Chuang. A Versatile Conformational Switch Regulates Reactivity in Human Branched-Chain Alpha-Ketoacid Dehydrogenase. Structure V. 14 287 2006.
ISSN: ISSN 0969-2126
PubMed: 16472748
DOI: 10.1016/J.STR.2005.10.009
Page generated: Sat Oct 5 13:33:37 2024

Last articles

Mg in 1IDO
Mg in 1IDE
Mg in 1IDC
Mg in 1ID0
Mg in 1ICK
Mg in 1ICC
Mg in 1IBR
Mg in 1IAQ
Mg in 1IAH
Mg in 1I9V
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy