Manganese in PDB 9ljr: Structural Insights Into the Polymerase Catalyzed Fad-Capping of Hepatitis C Viral Rna

All present enzymatic activity of Structural Insights Into the Polymerase Catalyzed Fad-Capping of Hepatitis C Viral Rna:
2.7.7.48;

The structure of Structural Insights Into the Polymerase Catalyzed Fad-Capping of Hepatitis C Viral Rna, PDB code: 9ljr was solved by D.P.Wang, R.Zhao, W.S.Hu, H.N.Li, J.M.Cao, X.Zhou, Y.Xiang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	69.44 / 2.74
Space group	P 65
Cell size a, b, c (Å), α, β, γ (°)	138.876, 138.876, 93.227, 90, 90, 120
R / Rfree (%)	17.2 / 21.9

The binding sites of Manganese atom in the Structural Insights Into the Polymerase Catalyzed Fad-Capping of Hepatitis C Viral Rna (pdb code 9ljr). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Structural Insights Into the Polymerase Catalyzed Fad-Capping of Hepatitis C Viral Rna, PDB code: 9ljr:
Jump to Manganese binding site number: 1; 2;

Manganese binding site 1 out of 2 in the Structural Insights Into the Polymerase Catalyzed Fad-Capping of Hepatitis C Viral Rna


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Structural Insights Into the Polymerase Catalyzed Fad-Capping of Hepatitis C Viral Rna within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn603 b:37.9 occ:1.00 O2A A:CDP601 2.1 47.5 1.0 O A:THR221 2.2 43.3 1.0 OD2 A:ASP318 2.2 41.8 1.0 O1B A:CDP601 2.3 35.5 1.0 O A:HOH791 2.4 35.7 1.0 OD1 A:ASP220 2.5 38.6 1.0 CG A:ASP220 3.1 41.9 1.0 OD2 A:ASP220 3.2 44.3 1.0 CG A:ASP318 3.2 40.9 1.0 C A:THR221 3.3 39.9 1.0 PA A:CDP601 3.4 41.4 1.0 PB A:CDP601 3.5 40.2 1.0 OD1 A:ASP318 3.5 38.6 1.0 MN A:MN604 3.6 78.3 1.0 N A:THR221 3.7 38.5 1.0 O3A A:CDP601 3.8 45.3 1.0 CA A:THR221 4.0 38.7 1.0 C5' A:CDP601 4.1 38.4 1.0 O2B A:CDP601 4.2 36.9 1.0 O5' A:CDP601 4.3 42.5 1.0 N A:HIS223 4.3 38.7 1.0 C A:ASP220 4.4 37.9 1.0 N A:PHE224 4.4 36.8 1.0 N A:ARG222 4.4 43.8 1.0 CB A:PHE224 4.4 35.1 1.0 O A:HOH798 4.5 45.4 1.0 O1A A:CDP601 4.5 40.0 1.0 CB A:ASP220 4.5 38.6 1.0 CB A:ASP318 4.5 32.1 1.0 CB A:THR221 4.6 36.7 1.0 CA A:ARG222 4.7 45.2 1.0 O3B A:CDP601 4.7 39.8 1.0 C A:ARG222 4.8 43.3 1.0 CA A:ASP220 4.8 34.5 1.0 CA A:PHE224 5.0 33.6 1.0

Manganese binding site 2 out of 2 in the Structural Insights Into the Polymerase Catalyzed Fad-Capping of Hepatitis C Viral Rna


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Structural Insights Into the Polymerase Catalyzed Fad-Capping of Hepatitis C Viral Rna within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn604 b:78.3 occ:1.00 OD1 A:ASP319 2.3 52.2 1.0 O2A A:CDP601 2.5 47.5 1.0 OD1 A:ASP220 2.6 38.6 1.0 OD1 A:ASP318 2.7 38.6 1.0 O3B A:FAD602 2.7 52.4 1.0 O A:HOH716 3.0 64.4 1.0 O1A A:CDP601 3.1 40.0 1.0 PA A:CDP601 3.3 41.4 1.0 CG A:ASP319 3.4 50.8 1.0 MN A:MN603 3.6 37.9 1.0 CG A:ASP318 3.7 40.9 1.0 C3B A:FAD602 3.7 53.7 1.0 CG A:ASP220 3.7 41.9 1.0 OD2 A:ASP318 3.9 41.8 1.0 OD2 A:ASP319 3.9 63.9 1.0 O5' A:CDP601 4.0 42.5 1.0 O1A A:FAD602 4.3 67.3 1.0 C5' A:CDP601 4.4 38.4 1.0 O A:HOH791 4.4 35.7 1.0 OD2 A:ASP220 4.5 44.3 1.0 CB A:ASP319 4.5 40.9 1.0 CB A:ASP220 4.6 38.6 1.0 O3A A:CDP601 4.7 45.3 1.0 C2B A:FAD602 4.7 53.7 1.0 N A:ASP319 4.8 38.9 1.0 C4B A:FAD602 4.8 57.7 1.0 C A:ASP318 4.8 37.4 1.0 O A:HOH712 4.9 50.4 1.0 O2B A:FAD602 4.9 50.9 1.0 CA A:ASP319 4.9 39.9 1.0

D.P.Wang, R.Zhao, W.S.Hu, H.N.Li, J.M.Cao, X.Zhou, Y.Xiang. Structural Insights Into the Polymerase Catalyzed Fad-Capping of Hepatitis C Viral Rna To Be Published.