Manganese in PDB 9h6j: Human B4GALNT1 Apo Structure

All present enzymatic activity of Human B4GALNT1 Apo Structure:
2.4.1.92;

The structure of Human B4GALNT1 Apo Structure, PDB code: 9h6j was solved by J.W.J.Welland, J.E.Deane, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	86.94 / 2.96
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	60.463, 136.486, 87.427, 90, 96.08, 90
R / Rfree (%)	20.2 / 25.4

The binding sites of Manganese atom in the Human B4GALNT1 Apo Structure (pdb code 9h6j). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Human B4GALNT1 Apo Structure, PDB code: 9h6j:
Jump to Manganese binding site number: 1; 2;

Manganese binding site 1 out of 2 in the Human B4GALNT1 Apo Structure


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Human B4GALNT1 Apo Structure within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn601 b:160.9 occ:1.00 OD2 A:ASP358 1.8 125.5 1.0 NE2 A:HIS483 2.8 125.0 1.0 CG A:ASP358 2.9 104.1 1.0 CE1 A:HIS483 3.4 125.0 1.0 OD1 A:ASP358 3.4 114.3 1.0 NH1 A:ARG288 3.9 128.0 1.0 CD2 A:HIS483 4.0 121.4 1.0 CB A:ASP358 4.2 98.7 1.0 NH2 A:ARG288 4.3 140.1 1.0 CZ A:ARG288 4.6 134.0 1.0 ND1 A:HIS483 4.7 126.0 1.0

Manganese binding site 2 out of 2 in the Human B4GALNT1 Apo Structure


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Human B4GALNT1 Apo Structure within 5.0Å range: probe atom residue distance (Å) B Occ B:Mn601 b:149.0 occ:1.00 OD2 B:ASP358 2.3 104.5 1.0 NE2 B:HIS483 2.9 120.6 1.0 CG B:ASP358 3.3 98.9 1.0 CE1 B:HIS483 3.4 126.0 1.0 OD1 B:ASP358 3.6 112.6 1.0 CD2 B:HIS483 4.2 107.6 1.0 ND1 B:HIS483 4.6 109.1 1.0 NH1 B:ARG288 4.7 138.5 1.0 CB B:ASP358 4.7 99.8 1.0 NH2 B:ARG288 4.8 125.8 1.0

J.W.J.Welland, H.G.Barrow, P.J.Stansfeld, J.E.Deane. Conformational Dynamics and Membrane Insertion Mechanism of B4GALNT1 in Ganglioside Synthesis. Nat Commun V. 16 5442 2025.
ISSN: ESSN 2041-1723
PubMed: 40593514
DOI: 10.1038/S41467-025-60593-9