Manganese in PDB 9c9w: Dimerized Human TOP3B-TDRD3 Core Complex with A Dna Mismatch Bubble

All present enzymatic activity of Dimerized Human TOP3B-TDRD3 Core Complex with A Dna Mismatch Bubble:
5.6.2.1;

The binding sites of Manganese atom in the Dimerized Human TOP3B-TDRD3 Core Complex with A Dna Mismatch Bubble (pdb code 9c9w). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Dimerized Human TOP3B-TDRD3 Core Complex with A Dna Mismatch Bubble, PDB code: 9c9w:

Manganese binding site 1 out of 1 in the Dimerized Human TOP3B-TDRD3 Core Complex with A Dna Mismatch Bubble


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Dimerized Human TOP3B-TDRD3 Core Complex with A Dna Mismatch Bubble within 5.0Å range: probe atom residue distance (Å) B Occ E:Mn101 b:165.8 occ:1.00 O3' E:DA24 2.1 115.3 1.0 C3' E:DA24 2.6 115.3 1.0 OE2 C:GLU9 2.7 114.3 1.0 C4' E:DA24 3.0 115.3 1.0 C5' E:DA24 3.3 115.3 1.0 O5' E:DA24 3.6 115.3 1.0 O2P C:PTR336 3.7 103.1 1.0 CD C:GLU9 3.8 114.3 1.0 O1P C:PTR336 4.1 103.1 1.0 P C:PTR336 4.1 103.1 1.0 C2' E:DA24 4.1 115.3 1.0 OE1 C:GLU9 4.3 114.3 1.0 OD2 C:ASP117 4.3 112.4 1.0 O4' E:DA24 4.4 115.3 1.0 O3P C:PTR336 4.4 103.1 1.0 C1' E:DA24 4.8 115.3 1.0 CG C:GLU9 5.0 114.3 1.0

X.Yang, X.Chen, W.Yang, Y.Pommier. Structural Insights Into Human Topoisomerase 3 Beta Dna and Rna Catalysis and Nucleic Acid Gate Dynamics. Nat Commun V. 16 834 2025.
ISSN: ESSN 2041-1723
PubMed: 39828754
DOI: 10.1038/S41467-025-55959-Y