Manganese in PDB 9c28: Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease

All present enzymatic activity of Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease:
2.3.1.225; 6.3.1.2;

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20;

Binding sites:

The binding sites of Manganese atom in the Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease (pdb code 9c28). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 20 binding sites of Manganese where determined in the Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease, PDB code: 9c28:
Jump to Manganese binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Manganese binding site 1 out of 20 in the Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn401 b:30.0 occ:1.00 MN A:MN402 3.1 30.0 1.0 OE1 A:GLU134 3.4 72.0 1.0 ND1 A:HIS253 3.7 75.0 1.0 NH2 A:ARG340 3.7 87.8 1.0 OE2 A:GLU338 3.7 89.3 1.0 CE1 A:HIS253 4.1 78.7 1.0 NH1 A:ARG319 4.1 113.0 1.0 CD A:GLU134 4.3 69.9 1.0 CD A:GLU338 4.7 94.0 1.0 OE2 A:GLU134 4.7 67.0 1.0 OE1 A:GLU338 4.7 96.7 1.0 CZ A:ARG340 4.9 83.8 1.0 CG A:HIS253 5.0 78.7 1.0

Manganese binding site 2 out of 20 in the Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn402 b:30.0 occ:1.00 OE1 A:GLU203 2.6 63.7 1.0 MN A:MN401 3.1 30.0 1.0 OE2 A:GLU203 3.2 60.2 1.0 CD A:GLU203 3.2 64.7 1.0 OE2 A:GLU196 3.5 63.8 1.0 OE2 A:GLU136 3.7 70.0 1.0 OE1 A:GLU134 3.8 72.0 1.0 OE1 A:GLU196 3.9 69.8 1.0 CD A:GLU196 4.1 67.1 1.0 ND2 A:ASN194 4.2 57.4 1.0 CG A:GLU203 4.7 57.0 1.0 CE1 A:HIS253 4.8 78.7 1.0 ND1 A:HIS253 4.9 75.0 1.0 CD A:GLU136 4.9 74.5 1.0 OD1 A:ASN194 4.9 48.6 1.0

Manganese binding site 3 out of 20 in the Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 3 of Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease within 5.0Å range: probe atom residue distance (Å) B Occ B:Mn401 b:30.0 occ:1.00 MN B:MN402 3.1 30.0 1.0 OE1 B:GLU134 3.4 72.0 1.0 ND1 B:HIS253 3.7 75.0 1.0 NH2 B:ARG340 3.7 87.8 1.0 OE2 B:GLU338 3.7 89.3 1.0 CE1 B:HIS253 4.1 78.7 1.0 NH1 B:ARG319 4.1 113.0 1.0 CD B:GLU134 4.3 69.9 1.0 CD B:GLU338 4.7 94.0 1.0 OE2 B:GLU134 4.7 67.0 1.0 OE1 B:GLU338 4.7 96.7 1.0 CZ B:ARG340 4.9 83.8 1.0 CG B:HIS253 5.0 78.7 1.0

Manganese binding site 4 out of 20 in the Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 4 of Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease within 5.0Å range: probe atom residue distance (Å) B Occ B:Mn402 b:30.0 occ:1.00 OE1 B:GLU203 2.6 63.7 1.0 MN B:MN401 3.1 30.0 1.0 OE2 B:GLU203 3.2 60.2 1.0 CD B:GLU203 3.2 64.7 1.0 OE2 B:GLU196 3.5 63.8 1.0 OE2 B:GLU136 3.7 70.0 1.0 OE1 B:GLU134 3.8 72.0 1.0 OE1 B:GLU196 3.9 69.8 1.0 CD B:GLU196 4.1 67.1 1.0 ND2 B:ASN194 4.2 57.4 1.0 CG B:GLU203 4.7 57.0 1.0 CE1 B:HIS253 4.8 78.7 1.0 ND1 B:HIS253 4.9 75.0 1.0 CD B:GLU136 4.9 74.5 1.0 OD1 B:ASN194 4.9 48.6 1.0

Manganese binding site 5 out of 20 in the Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 5 of Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease within 5.0Å range: probe atom residue distance (Å) B Occ C:Mn401 b:30.0 occ:1.00 MN C:MN402 3.1 30.0 1.0 OE1 C:GLU134 3.4 72.0 1.0 ND1 C:HIS253 3.7 75.0 1.0 NH2 C:ARG340 3.7 87.8 1.0 OE2 C:GLU338 3.7 89.3 1.0 CE1 C:HIS253 4.1 78.7 1.0 NH1 C:ARG319 4.1 113.0 1.0 CD C:GLU134 4.3 69.9 1.0 CD C:GLU338 4.7 94.0 1.0 OE2 C:GLU134 4.7 67.0 1.0 OE1 C:GLU338 4.7 96.7 1.0 CZ C:ARG340 4.9 83.8 1.0 CG C:HIS253 5.0 78.7 1.0

Manganese binding site 6 out of 20 in the Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 6 of Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease within 5.0Å range: probe atom residue distance (Å) B Occ C:Mn402 b:30.0 occ:1.00 OE1 C:GLU203 2.6 63.7 1.0 MN C:MN401 3.1 30.0 1.0 OE2 C:GLU203 3.2 60.2 1.0 CD C:GLU203 3.2 64.7 1.0 OE2 C:GLU196 3.5 63.8 1.0 OE2 C:GLU136 3.7 70.0 1.0 OE1 C:GLU134 3.8 72.0 1.0 OE1 C:GLU196 3.9 69.8 1.0 CD C:GLU196 4.1 67.1 1.0 ND2 C:ASN194 4.2 57.4 1.0 CG C:GLU203 4.7 57.0 1.0 CE1 C:HIS253 4.8 78.7 1.0 ND1 C:HIS253 4.9 75.0 1.0 CD C:GLU136 4.9 74.5 1.0 OD1 C:ASN194 4.9 48.6 1.0

Manganese binding site 7 out of 20 in the Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 7 of Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease within 5.0Å range: probe atom residue distance (Å) B Occ D:Mn401 b:30.0 occ:1.00 MN D:MN402 3.1 30.0 1.0 OE1 D:GLU134 3.4 72.0 1.0 ND1 D:HIS253 3.7 75.0 1.0 NH2 D:ARG340 3.7 87.8 1.0 OE2 D:GLU338 3.7 89.3 1.0 CE1 D:HIS253 4.1 78.7 1.0 NH1 D:ARG319 4.1 113.0 1.0 CD D:GLU134 4.3 69.9 1.0 CD D:GLU338 4.7 94.0 1.0 OE2 D:GLU134 4.7 67.0 1.0 OE1 D:GLU338 4.7 96.7 1.0 CZ D:ARG340 4.9 83.8 1.0 CG D:HIS253 5.0 78.7 1.0

Manganese binding site 8 out of 20 in the Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 8 of Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease within 5.0Å range: probe atom residue distance (Å) B Occ D:Mn402 b:30.0 occ:1.00 OE1 D:GLU203 2.6 63.7 1.0 MN D:MN401 3.1 30.0 1.0 OE2 D:GLU203 3.2 60.2 1.0 CD D:GLU203 3.2 64.7 1.0 OE2 D:GLU196 3.5 63.8 1.0 OE2 D:GLU136 3.7 70.0 1.0 OE1 D:GLU134 3.8 72.0 1.0 OE1 D:GLU196 3.9 69.8 1.0 CD D:GLU196 4.1 67.1 1.0 ND2 D:ASN194 4.2 57.4 1.0 CG D:GLU203 4.7 57.0 1.0 CE1 D:HIS253 4.8 78.7 1.0 ND1 D:HIS253 4.9 75.0 1.0 CD D:GLU136 4.9 74.5 1.0 OD1 D:ASN194 4.9 48.6 1.0

Manganese binding site 9 out of 20 in the Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 9 of Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease within 5.0Å range: probe atom residue distance (Å) B Occ E:Mn401 b:30.0 occ:1.00 MN E:MN402 3.1 30.0 1.0 OE1 E:GLU134 3.4 72.0 1.0 ND1 E:HIS253 3.7 75.0 1.0 NH2 E:ARG340 3.7 87.8 1.0 OE2 E:GLU338 3.7 89.3 1.0 CE1 E:HIS253 4.1 78.7 1.0 NH1 E:ARG319 4.1 113.0 1.0 CD E:GLU134 4.3 69.9 1.0 CD E:GLU338 4.7 94.0 1.0 OE2 E:GLU134 4.7 67.0 1.0 OE1 E:GLU338 4.7 96.7 1.0 CZ E:ARG340 4.9 83.8 1.0 CG E:HIS253 5.0 78.7 1.0

Manganese binding site 10 out of 20 in the Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 10 of Structure of Endogenous Glutamine Synthetase From Rat Model of Alzheimer'S Disease within 5.0Å range: probe atom residue distance (Å) B Occ E:Mn402 b:30.0 occ:1.00 OE1 E:GLU203 2.6 63.7 1.0 MN E:MN401 3.1 30.0 1.0 OE2 E:GLU203 3.2 60.2 1.0 CD E:GLU203 3.2 64.7 1.0 OE2 E:GLU196 3.5 63.8 1.0 OE2 E:GLU136 3.7 70.0 1.0 OE1 E:GLU134 3.8 72.0 1.0 OE1 E:GLU196 3.9 69.8 1.0 CD E:GLU196 4.1 67.1 1.0 ND2 E:ASN194 4.2 57.4 1.0 CG E:GLU203 4.7 57.0 1.0 CE1 E:HIS253 4.8 78.7 1.0 ND1 E:HIS253 4.9 75.0 1.0 CD E:GLU136 4.9 74.5 1.0 OD1 E:ASN194 4.9 48.6 1.0

E.K.Samani, S.M.N.Hasan, M.Waas, A.F.A.Keszei, X.Xu, M.Heydari, M.E.Hill, J.Mclaurin, T.Kislinger, M.T.Mazhab-Jafari. Unveiling the Structural Proteome of An Alzheimer'S Disease Rat Brain Model. Structure 2024.
ISSN: ISSN 0969-2126
PubMed: 39615488
DOI: 10.1016/J.STR.2024.11.004