Atomistry » Manganese » PDB 8sln-8uwb » 8sw5
Atomistry »
  Manganese »
    PDB 8sln-8uwb »
      8sw5 »

Manganese in PDB 8sw5: Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 1

Enzymatic activity of Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 1

All present enzymatic activity of Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 1:
3.1.3.16;

Protein crystallography data

The structure of Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 1, PDB code: 8sw5 was solved by M.S.Choy, W.Peti, R.Page, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 38.36 / 2.39
Space group P 41 21 2
Cell size a, b, c (Å), α, β, γ (°) 92.876, 92.876, 200.107, 90, 90, 90
R / Rfree (%) 21 / 25.2

Manganese Binding Sites:

The binding sites of Manganese atom in the Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 1 (pdb code 8sw5). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 4 binding sites of Manganese where determined in the Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 1, PDB code: 8sw5:
Jump to Manganese binding site number: 1; 2; 3; 4;

Manganese binding site 1 out of 4 in 8sw5

Go back to Manganese Binding Sites List in 8sw5
Manganese binding site 1 out of 4 in the Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 1


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 1 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mn401

b:43.4
occ:1.00
 NE2 A:HIS173 2.2 39.1 1.0
OD1 A:ASN124 2.2 47.0 1.0
O A:HOH516 2.2 46.8 1.0
ND1 A:HIS248 2.2 48.0 1.0
O2 A:PO4403 2.2 45.2 1.0
OD2 A:ASP92 2.3 46.7 1.0
CE1 A:HIS248 2.9 49.7 1.0
CE1 A:HIS173 3.1 40.7 1.0
CG A:ASN124 3.1 46.5 1.0
CD2 A:HIS173 3.2 47.5 1.0
CG A:ASP92 3.2 48.8 1.0
MN A:MN402 3.3 45.7 1.0
CG A:HIS248 3.4 45.0 1.0
P A:PO4403 3.4 55.4 1.0
ND2 A:ASN124 3.5 41.6 1.0
OD1 A:ASP92 3.5 44.9 1.0
O4 A:PO4403 3.5 46.9 1.0
CA A:HIS248 3.7 47.4 1.0
CB A:HIS248 3.9 44.7 1.0
OD2 A:ASP64 4.1 51.8 1.0
NE2 A:HIS248 4.1 50.1 1.0
O A:HIS248 4.2 52.7 1.0
O1 A:PO4403 4.2 55.2 1.0
ND1 A:HIS173 4.2 43.5 1.0
CG A:HIS173 4.3 43.7 1.0
CD2 A:HIS125 4.4 48.4 1.0
CD2 A:HIS248 4.4 45.7 1.0
C A:HIS248 4.4 50.4 1.0
CB A:ASP92 4.5 45.6 1.0
CB A:ASN124 4.5 46.2 1.0
N A:ASN124 4.6 39.0 1.0
O3 A:PO4403 4.6 43.2 1.0
N A:HIS248 4.7 39.9 1.0
O A:LEU205 4.7 49.8 1.0
CG A:ASP64 5.0 45.8 1.0

Manganese binding site 2 out of 4 in 8sw5

Go back to Manganese Binding Sites List in 8sw5
Manganese binding site 2 out of 4 in the Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 1


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 1 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mn402

b:45.7
occ:1.00
 O4 A:PO4403 2.0 46.9 1.0
OD2 A:ASP64 2.1 51.8 1.0
O A:HOH516 2.1 46.8 1.0
O A:HOH507 2.2 51.1 1.0
OD2 A:ASP92 2.2 46.7 1.0
NE2 A:HIS66 2.2 47.7 1.0
CD2 A:HIS66 3.2 44.6 1.0
CE1 A:HIS66 3.2 42.7 1.0
CG A:ASP92 3.2 48.8 1.0
P A:PO4403 3.3 55.4 1.0
CG A:ASP64 3.3 45.8 1.0
MN A:MN401 3.3 43.4 1.0
O2 A:PO4403 3.6 45.2 1.0
CB A:ASP92 3.6 45.6 1.0
O1 A:PO4403 3.9 55.2 1.0
CB A:ASP64 4.1 44.9 1.0
NH1 A:ARG96 4.1 55.5 1.0
OD1 A:ASP64 4.2 54.7 1.0
OH A:TYR272 4.2 60.0 1.0
ND1 A:HIS66 4.3 45.0 1.0
OD1 A:ASP92 4.3 44.9 1.0
CG A:HIS66 4.3 47.2 1.0
CD2 A:HIS125 4.3 48.4 1.0
O3 A:PO4403 4.4 43.2 1.0
NE2 A:HIS173 4.5 39.1 1.0
CE1 A:HIS173 4.5 40.7 1.0
NE2 A:HIS125 4.6 44.3 1.0
CE1 A:PHE267 4.7 49.4 1.0
O A:HIS248 4.8 52.7 1.0
CA A:HIS248 4.8 47.4 1.0
C A:HIS248 4.9 50.4 1.0
OD1 A:ASN124 5.0 47.0 1.0

Manganese binding site 3 out of 4 in 8sw5

Go back to Manganese Binding Sites List in 8sw5
Manganese binding site 3 out of 4 in the Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 1


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 3 of Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 1 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mn401

b:67.7
occ:1.00
 OD2 B:ASP64 2.2 66.6 1.0
O B:HOH513 2.2 63.0 1.0
O B:HOH506 2.2 57.1 1.0
NE2 B:HIS66 2.2 67.3 1.0
OD2 B:ASP92 2.3 59.9 1.0
O1 B:PO4403 2.5 62.1 1.0
CD2 B:HIS66 3.1 60.7 1.0
CE1 B:HIS66 3.2 54.6 1.0
MN B:MN402 3.3 55.1 1.0
CG B:ASP92 3.3 54.0 1.0
O3 B:PO4403 3.3 56.6 1.0
CG B:ASP64 3.3 64.5 1.0
P B:PO4403 3.4 61.1 1.0
CB B:ASP92 3.7 58.1 1.0
O4 B:PO4403 3.9 62.6 1.0
CB B:ASP64 4.1 62.7 1.0
OH B:TYR272 4.1 77.2 1.0
NH1 B:ARG96 4.2 60.1 1.0
OD1 B:ASP64 4.2 68.5 1.0
CD2 B:HIS125 4.3 54.6 1.0
CG B:HIS66 4.3 63.5 1.0
ND1 B:HIS66 4.3 59.0 1.0
OD1 B:ASP92 4.4 49.1 1.0
NE2 B:HIS125 4.5 57.5 1.0
NE2 B:HIS173 4.5 49.7 1.0
CE1 B:HIS173 4.5 49.8 1.0
O2 B:PO4403 4.7 61.4 1.0
CE1 B:PHE267 4.8 68.0 1.0
CA B:HIS248 4.9 66.1 1.0
O B:HIS248 4.9 69.3 1.0
ND1 B:HIS248 5.0 65.4 1.0
OD1 B:ASN124 5.0 49.7 1.0
CZ B:TYR272 5.0 76.3 1.0

Manganese binding site 4 out of 4 in 8sw5

Go back to Manganese Binding Sites List in 8sw5
Manganese binding site 4 out of 4 in the Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 1


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 4 of Protein Phosphatase 1 in Complex with PP1-Specific Phosphatase Targeting Peptide (Phostap) Version 1 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mn402

b:55.1
occ:1.00
 O3 B:PO4403 2.0 56.6 1.0
O B:HOH506 2.2 57.1 1.0
OD2 B:ASP92 2.2 59.9 1.0
OD1 B:ASN124 2.2 49.7 1.0
NE2 B:HIS173 2.2 49.7 1.0
ND1 B:HIS248 2.2 65.4 1.0
CE1 B:HIS248 2.9 59.3 1.0
CG B:ASN124 3.1 48.7 1.0
CE1 B:HIS173 3.1 49.8 1.0
CG B:ASP92 3.2 54.0 1.0
CD2 B:HIS173 3.2 55.3 1.0
MN B:MN401 3.3 67.7 1.0
ND2 B:ASN124 3.3 50.3 1.0
P B:PO4403 3.3 61.1 1.0
CG B:HIS248 3.5 60.6 1.0
OD1 B:ASP92 3.6 49.1 1.0
CA B:HIS248 3.8 66.1 1.0
O1 B:PO4403 3.9 62.1 1.0
O4 B:PO4403 3.9 62.6 1.0
OD2 B:ASP64 3.9 66.6 1.0
CB B:HIS248 4.0 59.7 1.0
NE2 B:HIS248 4.1 57.6 1.0
CD2 B:HIS125 4.2 54.6 1.0
ND1 B:HIS173 4.3 58.9 1.0
O B:HIS248 4.3 69.3 1.0
CG B:HIS173 4.3 58.7 1.0
CD2 B:HIS248 4.4 62.4 1.0
O2 B:PO4403 4.4 61.4 1.0
CB B:ASP92 4.4 58.1 1.0
CB B:ASN124 4.5 47.1 1.0
C B:HIS248 4.5 62.3 1.0
N B:ASN124 4.7 52.6 1.0
O B:LEU205 4.8 60.8 1.0
CG B:ASP64 4.8 64.5 1.0
N B:HIS248 4.8 61.1 1.0
NE2 B:HIS125 4.9 57.5 1.0
OD1 B:ASP64 4.9 68.5 1.0

Reference:

M.S.Choy, H.T.Nguyen, A.N.Kettenbach, W.Peti, R.Page. A Protein Phosphatase 1 Specific Phosphatase Targeting Peptide (Phostap) to Identify the PP1 Phosphatome To Be Published.
Page generated: Sun Oct 6 13:54:33 2024

Last articles

Cl in 2REE
Cl in 2RDC
Cl in 2RD7
Cl in 2RCD
Cl in 2RCF
Cl in 2RC8
Cl in 2RBS
Cl in 2RB4
Cl in 2RBC
Cl in 2RAG
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy