Manganese in PDB 8sks: Human Liver Mitochondrial Superoxide Dismutase [Mn]

All present enzymatic activity of Human Liver Mitochondrial Superoxide Dismutase [Mn]:
1.15.1.1;

The binding sites of Manganese atom in the Human Liver Mitochondrial Superoxide Dismutase [Mn] (pdb code 8sks). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 4 binding sites of Manganese where determined in the Human Liver Mitochondrial Superoxide Dismutase [Mn], PDB code: 8sks:
Jump to Manganese binding site number: 1; 2; 3; 4;

Manganese binding site 1 out of 4 in the Human Liver Mitochondrial Superoxide Dismutase [Mn]


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Human Liver Mitochondrial Superoxide Dismutase [Mn] within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn301 b:105.7 occ:1.00 OD2 A:ASP183 1.9 97.7 1.0 NE2 A:HIS50 2.0 93.8 1.0 NE2 A:HIS187 2.0 95.1 1.0 NE2 A:HIS98 2.2 96.5 1.0 CE1 A:HIS50 2.8 93.8 1.0 CE1 A:HIS187 3.0 95.1 1.0 CD2 A:HIS187 3.0 95.1 1.0 CG A:ASP183 3.1 97.7 1.0 CE1 A:HIS98 3.1 96.5 1.0 CD2 A:HIS98 3.1 96.5 1.0 CD2 A:HIS50 3.1 93.8 1.0 OD1 A:ASP183 3.6 97.7 1.0 ND1 A:HIS50 4.0 93.8 1.0 ND1 A:HIS187 4.1 95.1 1.0 ND1 A:HIS98 4.1 96.5 1.0 CG A:HIS187 4.2 95.1 1.0 CG A:HIS50 4.2 93.8 1.0 CG A:HIS98 4.2 96.5 1.0 CB A:ASP183 4.3 97.7 1.0 CZ2 A:TRP147 4.3 99.7 1.0 CB A:TRP185 4.5 98.9 1.0 NE2 A:GLN167 4.6 102.9 1.0 CG A:TRP185 4.8 98.9 1.0 CH2 A:TRP147 5.0 99.7 1.0

Manganese binding site 2 out of 4 in the Human Liver Mitochondrial Superoxide Dismutase [Mn]


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Human Liver Mitochondrial Superoxide Dismutase [Mn] within 5.0Å range: probe atom residue distance (Å) B Occ B:Mn301 b:105.7 occ:1.00 OD2 B:ASP183 1.9 97.7 1.0 NE2 B:HIS50 2.0 93.8 1.0 NE2 B:HIS187 2.0 95.1 1.0 NE2 B:HIS98 2.2 96.5 1.0 CE1 B:HIS50 2.8 93.8 1.0 CE1 B:HIS187 3.0 95.1 1.0 CD2 B:HIS187 3.0 95.1 1.0 CG B:ASP183 3.1 97.7 1.0 CE1 B:HIS98 3.1 96.5 1.0 CD2 B:HIS98 3.1 96.5 1.0 CD2 B:HIS50 3.1 93.8 1.0 OD1 B:ASP183 3.6 97.7 1.0 ND1 B:HIS50 4.0 93.8 1.0 ND1 B:HIS187 4.1 95.1 1.0 ND1 B:HIS98 4.1 96.5 1.0 CG B:HIS187 4.2 95.1 1.0 CG B:HIS50 4.2 93.8 1.0 CG B:HIS98 4.2 96.5 1.0 CB B:ASP183 4.3 97.7 1.0 CZ2 B:TRP147 4.3 99.7 1.0 CB B:TRP185 4.5 98.9 1.0 NE2 B:GLN167 4.6 102.9 1.0 CG B:TRP185 4.8 98.9 1.0 CH2 B:TRP147 5.0 99.7 1.0

Manganese binding site 3 out of 4 in the Human Liver Mitochondrial Superoxide Dismutase [Mn]


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 3 of Human Liver Mitochondrial Superoxide Dismutase [Mn] within 5.0Å range: probe atom residue distance (Å) B Occ C:Mn301 b:105.7 occ:1.00 OD2 C:ASP183 1.9 97.7 1.0 NE2 C:HIS50 2.0 93.8 1.0 NE2 C:HIS187 2.0 95.1 1.0 NE2 C:HIS98 2.2 96.5 1.0 CE1 C:HIS50 2.8 93.8 1.0 CE1 C:HIS187 3.0 95.1 1.0 CD2 C:HIS187 3.0 95.1 1.0 CG C:ASP183 3.1 97.7 1.0 CE1 C:HIS98 3.1 96.5 1.0 CD2 C:HIS98 3.1 96.5 1.0 CD2 C:HIS50 3.1 93.8 1.0 OD1 C:ASP183 3.6 97.7 1.0 ND1 C:HIS50 4.0 93.8 1.0 ND1 C:HIS187 4.1 95.1 1.0 ND1 C:HIS98 4.1 96.5 1.0 CG C:HIS187 4.2 95.1 1.0 CG C:HIS50 4.2 93.8 1.0 CG C:HIS98 4.2 96.5 1.0 CB C:ASP183 4.3 97.7 1.0 CZ2 C:TRP147 4.3 99.7 1.0 CB C:TRP185 4.5 98.9 1.0 NE2 C:GLN167 4.6 102.9 1.0 CG C:TRP185 4.8 98.9 1.0 CH2 C:TRP147 5.0 99.7 1.0

Manganese binding site 4 out of 4 in the Human Liver Mitochondrial Superoxide Dismutase [Mn]


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 4 of Human Liver Mitochondrial Superoxide Dismutase [Mn] within 5.0Å range: probe atom residue distance (Å) B Occ D:Mn301 b:105.7 occ:1.00 OD2 D:ASP183 1.9 97.7 1.0 NE2 D:HIS50 2.0 93.8 1.0 NE2 D:HIS187 2.0 95.1 1.0 NE2 D:HIS98 2.2 96.5 1.0 CE1 D:HIS50 2.8 93.8 1.0 CE1 D:HIS187 3.0 95.1 1.0 CD2 D:HIS187 3.0 95.1 1.0 CG D:ASP183 3.1 97.7 1.0 CE1 D:HIS98 3.1 96.5 1.0 CD2 D:HIS98 3.1 96.5 1.0 CD2 D:HIS50 3.1 93.8 1.0 OD1 D:ASP183 3.6 97.7 1.0 ND1 D:HIS50 4.0 93.8 1.0 ND1 D:HIS187 4.1 95.1 1.0 ND1 D:HIS98 4.1 96.5 1.0 CG D:HIS187 4.2 95.1 1.0 CG D:HIS50 4.2 93.8 1.0 CG D:HIS98 4.2 96.5 1.0 CB D:ASP183 4.3 97.7 1.0 CZ2 D:TRP147 4.3 99.7 1.0 CB D:TRP185 4.5 98.9 1.0 NE2 D:GLN167 4.6 102.9 1.0 CG D:TRP185 4.8 98.9 1.0 CH2 D:TRP147 5.0 99.7 1.0

Z.Zhang, M.L.Tringides, C.E.Morgan, M.Miyagi, J.A.Mears, C.L.Hoppel, E.W.Yu. High-Resolution Structural Proteomics of Mitochondria Using the 'Build and Retrieve' Methodology. Mol.Cell Proteomics V. 22 00666 2023.
ISSN: ESSN 1535-9484
PubMed: 37839702
DOI: 10.1016/J.MCPRO.2023.100666