Manganese in PDB 8ppd: Human Inositol 1,4,5-Trisphosphate 3-Kinase A (IP3K) Catalytic Domain in Complex with Dl-6-Deoxy-6-Hydroxy-Methyl-Scyllo-Inositol 1,2,4- Trisphosphate/Atp/Mn

Enzymatic activity of Human Inositol 1,4,5-Trisphosphate 3-Kinase A (IP3K) Catalytic Domain in Complex with Dl-6-Deoxy-6-Hydroxy-Methyl-Scyllo-Inositol 1,2,4- Trisphosphate/Atp/Mn

Protein crystallography data

Manganese Binding Sites:

Manganese binding site 1 out of 2 in 8ppd

Manganese Binding Sites List in 8ppd

Manganese binding site 1 out of 2 in the Human Inositol 1,4,5-Trisphosphate 3-Kinase A (IP3K) Catalytic Domain in Complex with Dl-6-Deoxy-6-Hydroxy-Methyl-Scyllo-Inositol 1,2,4- Trisphosphate/Atp/Mn


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Human Inositol 1,4,5-Trisphosphate 3-Kinase A (IP3K) Catalytic Domain in Complex with Dl-6-Deoxy-6-Hydroxy-Methyl-Scyllo-Inositol 1,2,4- Trisphosphate/Atp/Mn within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn506 b:46.7 occ:0.50 O3G A:ATP504 1.9 56.2 0.9 O1A A:ATP504 2.0 31.9 0.9 O A:HOH649 2.1 29.4 1.0 OD2 A:ASP416 2.3 33.0 1.0 PG A:ATP504 2.9 62.6 0.9 O3B A:ATP504 3.0 51.2 0.9 CG A:ASP416 3.3 31.6 1.0 PA A:ATP504 3.3 37.3 0.9 CB A:ASP416 3.5 29.9 1.0 O2G A:ATP504 3.5 62.0 0.9 O A:HOH684 3.6 43.1 1.0 PB A:ATP504 3.9 45.6 0.9 O3A A:ATP504 3.9 41.2 0.9 O2B A:ATP504 3.9 46.0 0.9 O A:GLY397 4.1 30.5 1.0 O2A A:ATP504 4.1 36.1 0.9 O1G A:ATP504 4.2 56.5 0.9 OG A:SER399 4.3 28.3 1.0 OD1 A:ASP416 4.4 32.8 1.0 O5' A:ATP504 4.5 36.8 0.9 OD2 A:ASP262 4.6 46.0 1.0 C5' A:ATP504 4.7 36.0 0.9 CE A:LYS264 4.9 40.1 1.0 NZ A:LYS264 5.0 43.7 1.0 CA A:ASP416 5.0 27.5 1.0

Manganese binding site 2 out of 2 in 8ppd

Manganese Binding Sites List in 8ppd

Manganese binding site 2 out of 2 in the Human Inositol 1,4,5-Trisphosphate 3-Kinase A (IP3K) Catalytic Domain in Complex with Dl-6-Deoxy-6-Hydroxy-Methyl-Scyllo-Inositol 1,2,4- Trisphosphate/Atp/Mn


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Human Inositol 1,4,5-Trisphosphate 3-Kinase A (IP3K) Catalytic Domain in Complex with Dl-6-Deoxy-6-Hydroxy-Methyl-Scyllo-Inositol 1,2,4- Trisphosphate/Atp/Mn within 5.0Å range: probe atom residue distance (Å) B Occ B:Mn507 b:101.6 occ:0.90 O2G B:ATP505 1.9 53.3 0.5 OD2 B:ASP416 2.0 35.6 1.0 O1A B:ATP505 2.1 39.8 0.5 O1A B:ATP505 2.2 38.8 0.4 PG B:ATP505 2.4 57.9 0.5 O B:HOH650 2.5 35.4 1.0 O1G B:ATP505 2.6 55.5 0.5 O3B B:ATP505 2.8 54.7 0.5 CG B:ASP416 3.0 35.5 1.0 O2B B:ATP505 3.1 48.7 0.4 PA B:ATP505 3.3 38.4 0.5 O2B B:ATP505 3.3 55.1 0.5 PA B:ATP505 3.3 37.8 0.4 CB B:ASP416 3.5 31.0 1.0 PB B:ATP505 3.5 51.2 0.5 PB B:ATP505 3.5 47.2 0.4 O1B B:ATP505 3.6 50.5 0.4 O3A B:ATP505 3.7 48.1 0.5 O3A B:ATP505 3.7 44.8 0.4 O3G B:ATP505 3.9 49.6 0.5 O B:HOH662 3.9 46.7 1.0 OD1 B:ASP416 4.1 35.8 1.0 O2A B:ATP505 4.1 37.5 0.4 O2A B:ATP505 4.1 37.8 0.5 O B:GLY397 4.1 32.8 1.0 O5' B:ATP505 4.6 36.3 0.5 O5' B:ATP505 4.6 36.3 0.4 OG B:SER399 4.8 32.0 1.0 C5' B:ATP505 4.9 34.7 0.4 O1B B:ATP505 4.9 58.6 0.5 C5' B:ATP505 4.9 34.3 0.5 CA B:ASP416 5.0 29.5 1.0

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