Manganese in PDB 8pn9: Structure of Human Oligosaccharyltransferase Ost-A Complex Bound to Ngi-1

All present enzymatic activity of Structure of Human Oligosaccharyltransferase Ost-A Complex Bound to Ngi-1:
2.4.99.18;

The binding sites of Manganese atom in the Structure of Human Oligosaccharyltransferase Ost-A Complex Bound to Ngi-1 (pdb code 8pn9). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Structure of Human Oligosaccharyltransferase Ost-A Complex Bound to Ngi-1, PDB code: 8pn9:

Manganese binding site 1 out of 1 in the Structure of Human Oligosaccharyltransferase Ost-A Complex Bound to Ngi-1


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Structure of Human Oligosaccharyltransferase Ost-A Complex Bound to Ngi-1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn804 b:65.2 occ:1.00 OD2 A:ASP49 2.1 71.3 1.0 OD1 A:ASP167 2.2 70.6 1.0 OD2 A:ASP167 2.4 70.6 1.0 CG A:ASP167 2.6 70.6 1.0 CG A:ASP49 3.3 71.3 1.0 OD1 A:ASN168 3.3 68.2 1.0 O4 A:OTP805 3.7 64.8 1.0 CB A:ASP167 4.1 70.6 1.0 OD1 A:ASP49 4.1 71.3 1.0 CB A:ASP49 4.2 71.3 1.0 O5 A:OTP805 4.2 64.8 1.0 CG A:ASN168 4.4 68.2 1.0 N A:ASN168 4.6 68.2 1.0 P2 A:OTP805 4.6 64.8 1.0 O3 A:OTP805 4.8 64.8 1.0 P1 A:OTP805 4.8 64.8 1.0 ND2 A:ASN53 4.8 66.9 1.0 CA A:ASP167 4.8 70.6 1.0 ND2 A:ASN168 4.9 68.2 1.0 NH1 A:ARG405 5.0 65.9 1.0

B.L.Lampson, A.S.Ramirez, M.Baro, L.He, M.Hegde, V.Koduri, J.L.Pfaff, R.E.Hanna, J.Kowal, N.H.Shirole, Y.He, J.G.Doench, J.N.Contessa, K.P.Locher, W.G.Kaelin Jr.. Positive Selection Crispr Screens Reveal A Druggable Pocket in An Oligosaccharyltransferase Required For Inflammatory Signaling to Nf-Kappa B. Cell V. 187 2209 2024.
ISSN: ISSN 1097-4172
PubMed: 38670073
DOI: 10.1016/J.CELL.2024.03.022