Manganese in PDB 8og4: Exostosin-Like 3 Udp Complex

All present enzymatic activity of Exostosin-Like 3 Udp Complex:
2.4.1.223;

The structure of Exostosin-Like 3 Udp Complex, PDB code: 8og4 was solved by D.Sammon, E.Hohenester, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.52 / 2.10
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	121.617, 121.617, 259.537, 90, 90, 120
R / Rfree (%)	19.2 / 23.1

The binding sites of Manganese atom in the Exostosin-Like 3 Udp Complex (pdb code 8og4). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Exostosin-Like 3 Udp Complex, PDB code: 8og4:
Jump to Manganese binding site number: 1; 2;

Manganese binding site 1 out of 2 in the Exostosin-Like 3 Udp Complex


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Exostosin-Like 3 Udp Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn1001 b:105.9 occ:1.00 O2A A:UDP1002 2.1 101.2 1.0 O2B A:UDP1002 2.2 120.4 1.0 OD2 A:ASP746 2.5 94.3 1.0 OD1 A:ASP746 2.6 100.4 1.0 CG A:ASP746 2.9 92.4 1.0 PB A:UDP1002 2.9 109.5 1.0 O1B A:UDP1002 2.9 107.4 1.0 OD2 A:ASP744 3.2 75.9 1.0 HB3 A:ASP744 3.3 95.9 1.0 PA A:UDP1002 3.4 94.9 1.0 O3A A:UDP1002 3.5 102.7 1.0 HH22 A:ARG672 3.5 122.7 1.0 HB2 A:ASP744 3.7 95.9 1.0 CG A:ASP744 3.8 83.6 1.0 CB A:ASP744 3.8 79.8 1.0 NH2 A:ARG672 4.2 102.2 1.0 C5' A:UDP1002 4.3 80.5 1.0 HH21 A:ARG672 4.3 122.7 1.0 O5' A:UDP1002 4.3 85.5 1.0 O3B A:UDP1002 4.3 117.0 1.0 CB A:ASP746 4.4 81.2 1.0 O1A A:UDP1002 4.5 105.2 1.0 H A:ASP746 4.6 93.6 1.0 OD1 A:ASP744 4.8 88.3 1.0 HB2 A:ASP746 4.8 97.6 1.0 HB3 A:ASP746 4.8 97.6 1.0 C3' A:UDP1002 5.0 76.7 1.0

Manganese binding site 2 out of 2 in the Exostosin-Like 3 Udp Complex


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Exostosin-Like 3 Udp Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Mn1001 b:94.6 occ:1.00 O1A B:UDP1002 2.2 75.3 1.0 OD1 B:ASP746 2.2 91.9 1.0 O2B B:UDP1002 2.4 98.5 1.0 OD2 B:ASP746 2.8 88.6 1.0 CG B:ASP746 2.9 89.7 1.0 OD2 B:ASP744 3.0 84.9 1.0 O3B B:UDP1002 3.1 98.3 1.0 PB B:UDP1002 3.2 97.9 1.0 HB3 B:ASP744 3.3 89.3 1.0 HH22 B:ARG672 3.3 124.5 1.0 PA B:UDP1002 3.5 86.5 1.0 HB2 B:ASP744 3.6 89.3 1.0 O3A B:UDP1002 3.7 103.1 1.0 CB B:ASP744 3.7 74.4 1.0 CG B:ASP744 3.7 80.0 1.0 C5' B:UDP1002 4.0 71.5 1.0 NH2 B:ARG672 4.0 103.7 1.0 HH21 B:ARG672 4.2 124.5 1.0 O5' B:UDP1002 4.2 86.5 1.0 H B:ASP746 4.3 89.0 1.0 CB B:ASP746 4.4 82.0 1.0 O1B B:UDP1002 4.6 103.7 1.0 O2A B:UDP1002 4.7 93.4 1.0 HB3 B:ASP746 4.8 98.5 1.0 HH12 B:ARG672 4.8 127.9 1.0 HB2 B:ASP746 4.8 98.5 1.0 C3' B:UDP1002 4.8 82.2 1.0 OD1 B:ASP744 4.9 87.8 1.0 C4' B:UDP1002 4.9 63.4 1.0 N B:ASP746 5.0 74.1 1.0

D.Sammon, A.Krueger, M.Busse-Wicher, R.M.Morgan, S.M.Haslam, B.Schumann, D.C.Briggs, E.Hohenester. Molecular Mechanism of Decision-Making in Glycosaminoglycan Biosynthesis To Be Published.