Manganese in PDB 8k52: Cryo-Em Structure of Chitin Synthase

All present enzymatic activity of Cryo-Em Structure of Chitin Synthase:
2.4.1.16;

The binding sites of Manganese atom in the Cryo-Em Structure of Chitin Synthase (pdb code 8k52). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Cryo-Em Structure of Chitin Synthase, PDB code: 8k52:
Jump to Manganese binding site number: 1; 2;

Manganese binding site 1 out of 2 in the Cryo-Em Structure of Chitin Synthase


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Cryo-Em Structure of Chitin Synthase within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn1002 b:159.2 occ:1.00 O2B A:UDP1001 2.7 149.4 1.0 O2A A:UDP1001 2.8 142.3 1.0 PB A:UDP1001 3.9 155.6 1.0 PA A:UDP1001 4.0 144.9 1.0 OD2 A:ASP382 4.1 131.4 1.0 O A:VAL383 4.2 115.8 1.0 O3A A:UDP1001 4.3 147.6 1.0 O1B A:UDP1001 4.3 145.0 1.0 O5' A:UDP1001 4.3 139.1 1.0 OG1 A:THR523 4.7 119.7 1.0 C3' A:UDP1001 4.9 123.0 1.0 CB A:ASP382 5.0 119.6 1.0

Manganese binding site 2 out of 2 in the Cryo-Em Structure of Chitin Synthase


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Cryo-Em Structure of Chitin Synthase within 5.0Å range: probe atom residue distance (Å) B Occ B:Mn1002 b:166.7 occ:1.00 O2B B:UDP1001 2.1 145.8 1.0 O B:VAL383 3.5 120.8 1.0 PB B:UDP1001 3.6 154.3 1.0 O2A B:UDP1001 3.8 138.5 1.0 O1B B:UDP1001 4.3 146.9 1.0 O3A B:UDP1001 4.5 146.1 1.0 C B:VAL383 4.5 117.9 1.0 OG1 B:THR523 4.6 121.4 1.0 CG2 B:VAL383 4.6 112.7 1.0 O3B B:UDP1001 4.6 154.5 1.0 CB B:ASP382 4.7 119.2 1.0 PA B:UDP1001 4.7 144.1 1.0 C3' B:UDP1001 4.9 126.2 1.0 OE1 B:GLN245 4.9 129.7 1.0

S.Niu, L.Qi, X.Zhang, D.He, P.Li, H.Wang, Y.Bi. Chitin Translocation Is Functionally Coupled with Synthesis in Chitin Synthase. Int J Mol Sci V. 25 2024.
ISSN: ESSN 1422-0067
PubMed: 39519219
DOI: 10.3390/IJMS252111667