Manganese in PDB 8dnu: Human Brain Glutamine Synthetase

Enzymatic activity of Human Brain Glutamine Synthetase

All present enzymatic activity of Human Brain Glutamine Synthetase:
2.3.1.225; 6.3.1.2;

Manganese Binding Sites:

The binding sites of Manganese atom in the Human Brain Glutamine Synthetase (pdb code 8dnu). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 10 binding sites of Manganese where determined in the Human Brain Glutamine Synthetase, PDB code: 8dnu:
Jump to Manganese binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Manganese binding site 1 out of 10 in 8dnu

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Manganese binding site 1 out of 10 in the Human Brain Glutamine Synthetase


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Human Brain Glutamine Synthetase within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mn401

b:30.0
occ:1.00
 OE1 A:GLU134 3.5 20.0 1.0
OE2 A:GLU338 3.7 37.0 1.0
OE2 A:GLU134 4.0 20.0 1.0
OE1 A:GLU338 4.0 37.0 1.0
CD A:GLU134 4.2 20.0 1.0
CD A:GLU338 4.3 37.0 1.0
NH1 A:ARG319 4.3 42.4 1.0
ND1 A:HIS253 4.7 32.1 1.0

Manganese binding site 2 out of 10 in 8dnu

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Manganese binding site 2 out of 10 in the Human Brain Glutamine Synthetase


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Human Brain Glutamine Synthetase within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mn401

b:30.0
occ:1.00
 OE2 B:GLU338 3.6 37.0 1.0
OE1 B:GLU134 3.8 20.0 1.0
NH1 B:ARG319 3.9 42.4 1.0
OE1 B:GLU338 3.9 37.0 1.0
CD B:GLU338 4.2 37.0 1.0
OE2 B:GLU134 4.6 20.0 1.0
CD B:GLU134 4.7 20.0 1.0
ND1 B:HIS253 4.7 32.1 1.0
CZ B:ARG319 4.8 42.4 1.0
NH1 B:ARG324 4.9 40.7 1.0

Manganese binding site 3 out of 10 in 8dnu

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Manganese binding site 3 out of 10 in the Human Brain Glutamine Synthetase


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 3 of Human Brain Glutamine Synthetase within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Mn401

b:30.0
occ:1.00
 OE2 C:GLU338 3.6 37.0 1.0
OE1 C:GLU134 3.9 20.0 1.0
OE1 C:GLU338 3.9 37.0 1.0
NH1 C:ARG319 3.9 42.4 1.0
CD C:GLU338 4.2 37.0 1.0
OE2 C:GLU134 4.6 20.0 1.0
CD C:GLU134 4.7 20.0 1.0
ND1 C:HIS253 4.7 32.1 1.0
CZ C:ARG319 4.8 42.4 1.0
NH1 C:ARG324 4.9 40.7 1.0

Manganese binding site 4 out of 10 in 8dnu

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Manganese binding site 4 out of 10 in the Human Brain Glutamine Synthetase


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 4 of Human Brain Glutamine Synthetase within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Mn401

b:30.0
occ:1.00
 OE2 D:GLU338 3.7 37.0 1.0
NH1 D:ARG319 3.8 42.4 1.0
OE1 D:GLU134 3.9 20.0 1.0
OE1 D:GLU338 4.0 37.0 1.0
CD D:GLU338 4.2 37.0 1.0
OE2 D:GLU134 4.7 20.0 1.0
CZ D:ARG319 4.7 42.4 1.0
CD D:GLU134 4.8 20.0 1.0
ND1 D:HIS253 4.8 32.1 1.0
NH1 D:ARG324 4.9 40.7 1.0

Manganese binding site 5 out of 10 in 8dnu

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Manganese binding site 5 out of 10 in the Human Brain Glutamine Synthetase


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 5 of Human Brain Glutamine Synthetase within 5.0Å range:
probe atom residue distance (Å) B Occ
E:Mn401

b:30.0
occ:1.00
 OE1 E:GLU134 3.5 20.0 1.0
OE2 E:GLU338 3.6 37.0 1.0
OE1 E:GLU338 3.9 37.0 1.0
CD E:GLU338 4.2 37.0 1.0
NH1 E:ARG319 4.2 42.4 1.0
OE2 E:GLU134 4.4 20.0 1.0
CD E:GLU134 4.4 20.0 1.0
ND1 E:HIS253 4.6 32.1 1.0

Manganese binding site 6 out of 10 in 8dnu

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Manganese binding site 6 out of 10 in the Human Brain Glutamine Synthetase


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 6 of Human Brain Glutamine Synthetase within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Mn401

b:30.0
occ:1.00
 OE1 F:GLU134 3.5 20.0 1.0
OE2 F:GLU338 3.7 37.0 1.0
OE1 F:GLU338 4.0 37.0 1.0
CD F:GLU338 4.3 37.0 1.0
NH1 F:ARG319 4.3 42.4 1.0
CD F:GLU134 4.4 20.0 1.0
OE2 F:GLU134 4.4 20.0 1.0
ND1 F:HIS253 4.6 32.1 1.0

Manganese binding site 7 out of 10 in 8dnu

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Manganese binding site 7 out of 10 in the Human Brain Glutamine Synthetase


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 7 of Human Brain Glutamine Synthetase within 5.0Å range:
probe atom residue distance (Å) B Occ
G:Mn401

b:30.0
occ:1.00
 OE2 G:GLU338 3.6 37.0 1.0
OE1 G:GLU134 3.8 20.0 1.0
OE1 G:GLU338 3.9 37.0 1.0
NH1 G:ARG319 3.9 42.4 1.0
CD G:GLU338 4.2 37.0 1.0
OE2 G:GLU134 4.6 20.0 1.0
CD G:GLU134 4.7 20.0 1.0
ND1 G:HIS253 4.8 32.1 1.0
CZ G:ARG319 4.8 42.4 1.0
NH1 G:ARG324 4.9 40.7 1.0

Manganese binding site 8 out of 10 in 8dnu

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Manganese binding site 8 out of 10 in the Human Brain Glutamine Synthetase


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 8 of Human Brain Glutamine Synthetase within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Mn401

b:30.0
occ:1.00
 OE2 H:GLU338 3.6 37.0 1.0
OE1 H:GLU134 3.9 20.0 1.0
OE1 H:GLU338 3.9 37.0 1.0
NH1 H:ARG319 3.9 42.4 1.0
CD H:GLU338 4.1 37.0 1.0
OE2 H:GLU134 4.6 20.0 1.0
CD H:GLU134 4.7 20.0 1.0
ND1 H:HIS253 4.7 32.1 1.0
CZ H:ARG319 4.8 42.4 1.0
NH1 H:ARG324 4.8 40.7 1.0

Manganese binding site 9 out of 10 in 8dnu

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Manganese binding site 9 out of 10 in the Human Brain Glutamine Synthetase


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 9 of Human Brain Glutamine Synthetase within 5.0Å range:
probe atom residue distance (Å) B Occ
I:Mn401

b:30.0
occ:1.00
 OE2 I:GLU338 3.7 37.0 1.0
NH1 I:ARG319 3.8 42.4 1.0
OE1 I:GLU134 3.9 20.0 1.0
OE1 I:GLU338 4.0 37.0 1.0
CD I:GLU338 4.2 37.0 1.0
OE2 I:GLU134 4.7 20.0 1.0
CZ I:ARG319 4.7 42.4 1.0
CD I:GLU134 4.8 20.0 1.0
ND1 I:HIS253 4.8 32.1 1.0
NH1 I:ARG324 4.9 40.7 1.0

Manganese binding site 10 out of 10 in 8dnu

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Manganese binding site 10 out of 10 in the Human Brain Glutamine Synthetase


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 10 of Human Brain Glutamine Synthetase within 5.0Å range:
probe atom residue distance (Å) B Occ
J:Mn401

b:30.0
occ:1.00
 OE1 J:GLU134 3.5 20.0 1.0
OE2 J:GLU338 3.6 37.0 1.0
OE1 J:GLU338 3.9 37.0 1.0
CD J:GLU338 4.2 37.0 1.0
NH1 J:ARG319 4.2 42.4 1.0
OE2 J:GLU134 4.4 20.0 1.0
CD J:GLU134 4.4 20.0 1.0
ND1 J:HIS253 4.6 32.1 1.0

Reference:

M.L.Tringides, M.L.Tringides. N/A N/A.
Page generated: Fri Apr 7 13:25:22 2023

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