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Manganese in PDB 8d3m: Type I-C CAS4-CAS1-CAS2 Complex Bound to A Pam/Processed Prespacer

Enzymatic activity of Type I-C CAS4-CAS1-CAS2 Complex Bound to A Pam/Processed Prespacer

All present enzymatic activity of Type I-C CAS4-CAS1-CAS2 Complex Bound to A Pam/Processed Prespacer:
3.1.12.1;

Other elements in 8d3m:

The structure of Type I-C CAS4-CAS1-CAS2 Complex Bound to A Pam/Processed Prespacer also contains other interesting chemical elements:

Iron (Fe) 4 atoms

Manganese Binding Sites:

The binding sites of Manganese atom in the Type I-C CAS4-CAS1-CAS2 Complex Bound to A Pam/Processed Prespacer (pdb code 8d3m). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Type I-C CAS4-CAS1-CAS2 Complex Bound to A Pam/Processed Prespacer, PDB code: 8d3m:

Manganese binding site 1 out of 1 in 8d3m

Go back to Manganese Binding Sites List in 8d3m
Manganese binding site 1 out of 1 in the Type I-C CAS4-CAS1-CAS2 Complex Bound to A Pam/Processed Prespacer


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Type I-C CAS4-CAS1-CAS2 Complex Bound to A Pam/Processed Prespacer within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Mn401

b:66.9
occ:1.00
OP1 H:DG29 1.7 58.3 1.0
OD2 I:ASP82 1.9 74.6 1.0
O I:TYR109 2.7 68.3 1.0
P H:DG29 3.0 58.3 1.0
CG I:ASP82 3.1 74.6 1.0
CG I:GLU108 3.3 71.1 1.0
O3' H:DT28 3.6 61.8 1.0
OP2 H:DG29 3.6 58.3 1.0
OD1 I:ASP82 3.7 74.6 1.0
C I:TYR109 3.8 68.3 1.0
N I:TYR109 3.9 68.3 1.0
CD I:GLU108 4.0 71.1 1.0
O5' H:DG29 4.2 58.3 1.0
OE2 I:GLU108 4.2 71.1 1.0
CB I:ASP82 4.3 74.6 1.0
CA I:TYR109 4.4 68.3 1.0
C I:GLU108 4.6 71.1 1.0
CB I:GLU108 4.6 71.1 1.0
CB I:TYR109 4.7 68.3 1.0
CA I:GLU108 4.7 71.1 1.0
C3' H:DT28 4.7 61.8 1.0
C5' H:DG29 4.8 58.3 1.0
OE1 I:GLU108 4.8 71.1 1.0
CG I:LYS110 4.8 62.1 1.0
N I:LYS110 4.9 62.1 1.0
ND1 I:HIS47 4.9 63.5 1.0

Reference:

Y.Dhingra, S.K.Suresh, P.Juneja, D.G.Sashital. Pam Binding Ensures Orientational Integration During CAS4-CAS1-CAS2-Mediated Crispr Adaptation. Mol.Cell V. 82 4353 2022.
ISSN: ISSN 1097-2765
PubMed: 36272411
DOI: 10.1016/J.MOLCEL.2022.09.030
Page generated: Sun Oct 6 11:29:30 2024

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