Manganese in PDB 7zr1: Chaetomium Thermophilum MRE11-RAD50-NBS1 Complex Bound to Atpys (Composite Structure)

The structure of Chaetomium Thermophilum MRE11-RAD50-NBS1 Complex Bound to Atpys (Composite Structure) also contains other interesting chemical elements:

Magnesium

(Mg)

2 atoms

The binding sites of Manganese atom in the Chaetomium Thermophilum MRE11-RAD50-NBS1 Complex Bound to Atpys (Composite Structure) (pdb code 7zr1). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 4 binding sites of Manganese where determined in the Chaetomium Thermophilum MRE11-RAD50-NBS1 Complex Bound to Atpys (Composite Structure), PDB code: 7zr1:
Jump to Manganese binding site number: 1; 2; 3; 4;

Manganese binding site 1 out of 4 in the Chaetomium Thermophilum MRE11-RAD50-NBS1 Complex Bound to Atpys (Composite Structure)


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Chaetomium Thermophilum MRE11-RAD50-NBS1 Complex Bound to Atpys (Composite Structure) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn801 b:151.1 occ:1.00 OD1 A:ASP17 2.0 151.1 1.0 NE2 A:HIS19 2.3 151.1 1.0 OD2 A:ASP57 2.4 151.1 1.0 MN A:MN802 2.7 151.1 1.0 NE2 A:HIS243 2.7 151.1 1.0 CG A:ASP17 2.8 151.1 1.0 CE1 A:HIS19 2.9 151.1 1.0 CD2 A:HIS19 3.4 151.1 1.0 CG A:ASP57 3.4 151.1 1.0 CB A:ASP17 3.5 151.1 1.0 CD2 A:HIS243 3.6 151.1 1.0 OD2 A:ASP17 3.6 151.1 1.0 CE1 A:HIS243 3.7 151.1 1.0 CB A:ASP57 3.8 151.1 1.0 NE2 A:HIS213 3.8 151.1 1.0 ND1 A:HIS241 4.0 151.1 1.0 CE1 A:HIS213 4.1 151.1 1.0 ND1 A:HIS19 4.1 151.1 1.0 CE1 A:HIS241 4.1 151.1 1.0 CA A:ASP17 4.2 151.1 1.0 CG A:HIS19 4.3 151.1 1.0 O A:HIS241 4.4 151.1 1.0 OD1 A:ASP57 4.5 151.1 1.0 OD1 A:ASN124 4.7 151.1 1.0 CG A:HIS243 4.8 151.1 1.0 ND1 A:HIS243 4.8 151.1 1.0

Manganese binding site 2 out of 4 in the Chaetomium Thermophilum MRE11-RAD50-NBS1 Complex Bound to Atpys (Composite Structure)


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Chaetomium Thermophilum MRE11-RAD50-NBS1 Complex Bound to Atpys (Composite Structure) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn802 b:151.1 occ:1.00 NE2 A:HIS213 1.9 151.1 1.0 ND1 A:HIS241 2.0 151.1 1.0 OD2 A:ASP57 2.0 151.1 1.0 CE1 A:HIS241 2.3 151.1 1.0 OD1 A:ASN124 2.4 151.1 1.0 MN A:MN801 2.7 151.1 1.0 CD2 A:HIS213 2.8 151.1 1.0 CE1 A:HIS213 2.9 151.1 1.0 CG A:ASP57 3.1 151.1 1.0 OD1 A:ASP17 3.2 151.1 1.0 CG A:HIS241 3.4 151.1 1.0 CG A:ASN124 3.5 151.1 1.0 NE2 A:HIS241 3.6 151.1 1.0 OD1 A:ASP57 3.7 151.1 1.0 ND2 A:ASN124 3.9 151.1 1.0 ND1 A:HIS213 4.0 151.1 1.0 CG A:HIS213 4.0 151.1 1.0 CD2 A:HIS241 4.1 151.1 1.0 CB A:HIS241 4.2 151.1 1.0 CA A:HIS241 4.2 151.1 1.0 CG A:ASP17 4.2 151.1 1.0 CB A:ASP57 4.3 151.1 1.0 OD2 A:ASP17 4.5 151.1 1.0 O A:HIS241 4.6 151.1 1.0 NE2 A:HIS19 4.8 151.1 1.0 CB A:ASN124 4.8 151.1 1.0 O A:GLY240 4.9 151.1 1.0 C A:HIS241 4.9 151.1 1.0 N A:ASN124 4.9 151.1 1.0 NE2 A:HIS243 5.0 151.1 1.0

Manganese binding site 3 out of 4 in the Chaetomium Thermophilum MRE11-RAD50-NBS1 Complex Bound to Atpys (Composite Structure)


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 3 of Chaetomium Thermophilum MRE11-RAD50-NBS1 Complex Bound to Atpys (Composite Structure) within 5.0Å range: probe atom residue distance (Å) B Occ B:Mn801 b:151.1 occ:1.00 OD2 B:ASP17 1.9 151.1 1.0 NE2 B:HIS19 2.1 151.1 1.0 NE2 B:HIS243 2.3 151.1 1.0 CE1 B:HIS19 2.8 151.1 1.0 CG B:ASP17 2.9 151.1 1.0 MN B:MN802 3.0 151.1 1.0 CE1 B:HIS243 3.0 151.1 1.0 OD2 B:ASP57 3.1 151.1 1.0 CD2 B:HIS19 3.3 151.1 1.0 CD2 B:HIS243 3.4 151.1 1.0 CB B:ASP17 3.6 151.1 1.0 OD1 B:ASP17 3.8 151.1 1.0 ND1 B:HIS241 3.9 151.1 1.0 ND1 B:HIS19 4.0 151.1 1.0 O B:HIS241 4.0 151.1 1.0 CG B:ASP57 4.1 151.1 1.0 ND1 B:HIS243 4.2 151.1 1.0 CE1 B:HIS241 4.2 151.1 1.0 CE1 B:HIS216 4.3 150.6 1.0 CG B:HIS19 4.3 151.1 1.0 CG B:HIS243 4.4 151.1 1.0 CB B:ASP57 4.4 151.1 1.0 CA B:ASP17 4.5 151.1 1.0 CE1 B:HIS213 4.7 122.9 1.0 NE2 B:HIS213 4.8 122.9 1.0 C B:HIS241 4.9 151.1 1.0 NE2 B:HIS216 4.9 150.6 1.0 CA B:HIS241 5.0 151.1 1.0

Manganese binding site 4 out of 4 in the Chaetomium Thermophilum MRE11-RAD50-NBS1 Complex Bound to Atpys (Composite Structure)


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 4 of Chaetomium Thermophilum MRE11-RAD50-NBS1 Complex Bound to Atpys (Composite Structure) within 5.0Å range: probe atom residue distance (Å) B Occ B:Mn802 b:151.1 occ:1.00 OD2 B:ASP57 2.0 151.1 1.0 ND1 B:HIS241 2.0 151.1 1.0 CE1 B:HIS216 2.3 150.6 1.0 NE2 B:HIS213 2.4 122.9 1.0 NE2 B:HIS216 2.4 150.6 1.0 CE1 B:HIS241 2.6 151.1 1.0 MN B:MN801 3.0 151.1 1.0 CE1 B:HIS213 3.1 122.9 1.0 CG B:ASP57 3.2 151.1 1.0 CG B:HIS241 3.3 151.1 1.0 ND1 B:HIS216 3.4 150.6 1.0 CD2 B:HIS213 3.5 122.9 1.0 OD2 B:ASP17 3.6 151.1 1.0 CD2 B:HIS216 3.6 150.6 1.0 OD1 B:ASP57 3.7 151.1 1.0 CA B:HIS241 3.8 151.1 1.0 NE2 B:HIS241 3.9 151.1 1.0 CB B:HIS241 3.9 151.1 1.0 CG B:HIS216 4.0 150.6 1.0 CD2 B:HIS241 4.2 151.1 1.0 ND1 B:HIS213 4.3 122.9 1.0 CG B:ASP17 4.3 151.1 1.0 O B:HIS241 4.4 151.1 1.0 OD1 B:ASP17 4.4 151.1 1.0 CB B:ASP57 4.4 151.1 1.0 CG B:HIS213 4.5 122.9 1.0 C B:HIS241 4.6 151.1 1.0 NE2 B:HIS19 4.7 151.1 1.0 N B:HIS241 4.8 151.1 1.0 NE2 B:HIS243 4.8 151.1 1.0 CE1 B:HIS19 4.9 151.1 1.0

M.Rotheneder, K.Stakyte, E.Van De Logt, J.D.Bartho, K.Lammens, Y.Fan, A.Alt, B.Kessler, C.Jung, W.P.Roos, B.Steigenberger, K.P.Hopfner. Cryo-Em Structure of the MRE11-RAD50-NBS1 Complex Reveals the Molecular Mechanism of Scaffolding Functions. Mol.Cell 2022.
ISSN: ISSN 1097-2765
PubMed: 36577401
DOI: 10.1016/J.MOLCEL.2022.12.003