Manganese in PDB 7yaj: Cryoem Structure of SPCA1A in E1-Mn-Amppcp State Subclass 1

All present enzymatic activity of Cryoem Structure of SPCA1A in E1-Mn-Amppcp State Subclass 1:
7.2.2.10;

The binding sites of Manganese atom in the Cryoem Structure of SPCA1A in E1-Mn-Amppcp State Subclass 1 (pdb code 7yaj). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Cryoem Structure of SPCA1A in E1-Mn-Amppcp State Subclass 1, PDB code: 7yaj:

Manganese binding site 1 out of 1 in the Cryoem Structure of SPCA1A in E1-Mn-Amppcp State Subclass 1


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Cryoem Structure of SPCA1A in E1-Mn-Amppcp State Subclass 1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn1002 b:0.0 occ:1.00 OD2 A:ASP742 2.2 42.9 1.0 O A:VAL303 2.3 21.3 1.0 O A:ALA304 2.3 18.9 1.0 O A:ILE306 2.3 18.6 1.0 OD1 A:ASN738 2.5 37.7 1.0 C A:ALA304 3.1 14.2 1.0 CG A:ASP742 3.3 30.7 1.0 C A:VAL303 3.4 20.5 1.0 C A:ILE306 3.5 12.6 1.0 CA A:ALA304 3.6 14.9 1.0 CG A:ASN738 3.7 34.4 1.0 N A:ILE306 3.8 18.8 1.0 CG A:GLU308 3.9 15.7 1.0 N A:ALA304 4.0 18.3 1.0 N A:GLU308 4.1 37.5 1.0 CA A:ILE306 4.1 13.1 1.0 CB A:ASP742 4.2 35.6 1.0 OD1 A:ASP742 4.2 31.4 1.0 N A:ALA305 4.2 14.4 1.0 OE2 A:GLU308 4.2 18.3 1.0 CD A:GLU308 4.3 19.2 1.0 CB A:GLU308 4.4 22.0 1.0 C A:ALA305 4.4 11.7 1.0 CB A:ILE306 4.5 16.8 1.0 ND2 A:ASN738 4.5 40.0 1.0 N A:PRO307 4.5 7.2 1.0 CB A:ASN738 4.6 44.8 1.0 CA A:VAL303 4.7 14.2 1.0 CG A:MET741 4.7 36.1 1.0 CA A:PRO307 4.7 0.0 1.0 CA A:ALA305 4.8 5.3 1.0 SD A:MET741 4.8 13.3 1.0 CA A:GLU308 4.9 24.8 1.0 O A:ASN738 4.9 36.3 1.0 C A:PRO307 4.9 24.3 1.0 CG2 A:ILE306 4.9 15.6 1.0 CG1 A:VAL303 5.0 0.0 1.0 CB A:ALA304 5.0 14.0 1.0

Z.Chen, S.Watanabe, H.Hashida, M.Inoue, Y.Daigaku, M.Kikkawa, K.Inaba. Cryo-Em Structures of Human SPCA1A Reveal the Mechanism of Ca 2+ /Mn 2+ Transport Into the Golgi Apparatus. Sci Adv V. 9 D9742 2023.
ISSN: ESSN 2375-2548
PubMed: 36867705
DOI: 10.1126/SCIADV.ADD9742