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Manganese in PDB 7nro: Crystal Structure of Alkb in Complex with Manganese and N-(4-((6- ((Carboxymethyl)Carbamoyl)-5-Hydroxypyridin-2-Yl)Amino)Phenyl)-N- OxohydroxylammoniumEnzymatic activity of Crystal Structure of Alkb in Complex with Manganese and N-(4-((6- ((Carboxymethyl)Carbamoyl)-5-Hydroxypyridin-2-Yl)Amino)Phenyl)-N- Oxohydroxylammonium
All present enzymatic activity of Crystal Structure of Alkb in Complex with Manganese and N-(4-((6- ((Carboxymethyl)Carbamoyl)-5-Hydroxypyridin-2-Yl)Amino)Phenyl)-N- Oxohydroxylammonium:
1.14.11.33; Protein crystallography data
The structure of Crystal Structure of Alkb in Complex with Manganese and N-(4-((6- ((Carboxymethyl)Carbamoyl)-5-Hydroxypyridin-2-Yl)Amino)Phenyl)-N- Oxohydroxylammonium, PDB code: 7nro
was solved by
P.Maheswaran,
T.Leissing,
W.S.Aik,
M.A.Mcdonough,
C.J.Schofield,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Manganese Binding Sites:
The binding sites of Manganese atom in the Crystal Structure of Alkb in Complex with Manganese and N-(4-((6- ((Carboxymethyl)Carbamoyl)-5-Hydroxypyridin-2-Yl)Amino)Phenyl)-N- Oxohydroxylammonium
(pdb code 7nro). This binding sites where shown within
5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Crystal Structure of Alkb in Complex with Manganese and N-(4-((6- ((Carboxymethyl)Carbamoyl)-5-Hydroxypyridin-2-Yl)Amino)Phenyl)-N- Oxohydroxylammonium, PDB code: 7nro: Manganese binding site 1 out of 1 in 7nroGo back to Manganese Binding Sites List in 7nro
Manganese binding site 1 out
of 1 in the Crystal Structure of Alkb in Complex with Manganese and N-(4-((6- ((Carboxymethyl)Carbamoyl)-5-Hydroxypyridin-2-Yl)Amino)Phenyl)-N- Oxohydroxylammonium
Mono view Stereo pair view
Reference:
S.Shishodia,
M.Demetriades,
D.Zhang,
N.Tan,
P.Maheswaran,
C.Clunie-O'connor,
A.Tumber,
I.K.H.Leung,
Y.M.Ng,
T.M.Leissing,
A.H.El-Sagheer,
E.Salah,
T.Brown,
W.S.Aik,
M.A.Mcdonough,
C.J.Schofield.
Structure Based Design of Selective Fat Mass and Obesity Associated Protein (Fto) Inhibitors J.Med.Chem. 2021.
Page generated: Fri Nov 5 15:45:48 2021
ISSN: ISSN 0022-2623 DOI: 10.1021/ACS.JMEDCHEM.1C01204 |
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