Manganese in PDB 7k36: Cryo-Em Structure of Stripak Complex

All present enzymatic activity of Cryo-Em Structure of Stripak Complex:
3.1.3.16;

The structure of Cryo-Em Structure of Stripak Complex also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Manganese atom in the Cryo-Em Structure of Stripak Complex (pdb code 7k36). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Cryo-Em Structure of Stripak Complex, PDB code: 7k36:
Jump to Manganese binding site number: 1; 2;

Manganese binding site 1 out of 2 in the Cryo-Em Structure of Stripak Complex


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Cryo-Em Structure of Stripak Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Mn401 b:83.4 occ:1.00 OD1 C:ASP85 1.1 67.9 1.0 CG C:ASP85 1.9 67.9 1.0 OD1 C:ASN117 2.1 60.4 1.0 NE2 C:HIS167 2.2 56.5 1.0 OD2 C:ASP85 2.2 67.9 1.0 ND2 C:ASN117 2.3 60.4 1.0 CE1 C:HIS167 2.4 56.5 1.0 ND1 C:HIS241 2.5 57.5 1.0 CG C:ASN117 2.5 60.4 1.0 MN C:MN402 2.8 91.1 1.0 CE1 C:HIS241 2.9 57.5 1.0 OD1 C:ASP57 3.1 69.3 1.0 CB C:ASP85 3.3 67.9 1.0 CD2 C:HIS167 3.5 56.5 1.0 ND1 C:HIS167 3.7 56.5 1.0 CG C:HIS241 3.8 57.5 1.0 O C:HIS241 4.0 57.5 1.0 CB C:ASN117 4.0 60.4 1.0 CG C:ASP57 4.1 69.3 1.0 NE2 C:HIS241 4.2 57.5 1.0 CG C:HIS167 4.2 56.5 1.0 CA C:HIS241 4.3 57.5 1.0 OD2 C:ASP57 4.3 69.3 1.0 CA C:ASP85 4.4 67.9 1.0 NE2 C:HIS59 4.4 66.4 1.0 CE1 C:HIS59 4.5 66.4 1.0 CB C:HIS241 4.5 57.5 1.0 N C:ASN117 4.5 60.4 1.0 C C:HIS241 4.6 57.5 1.0 CD2 C:HIS241 4.6 57.5 1.0 O C:ALA240 4.7 58.1 1.0 CA C:ASN117 4.9 60.4 1.0 N C:ASP85 4.9 67.9 1.0

Manganese binding site 2 out of 2 in the Cryo-Em Structure of Stripak Complex


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Cryo-Em Structure of Stripak Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Mn402 b:91.1 occ:1.00 OD1 C:ASP85 2.1 67.9 1.0 OD1 C:ASP57 2.1 69.3 1.0 OD2 C:ASP57 2.2 69.3 1.0 NE2 C:HIS59 2.2 66.4 1.0 CG C:ASP57 2.4 69.3 1.0 MN C:MN401 2.8 83.4 1.0 CE1 C:HIS59 3.0 66.4 1.0 CG C:ASP85 3.0 67.9 1.0 CD2 C:HIS59 3.2 66.4 1.0 CB C:ASP85 3.5 67.9 1.0 O C:HIS241 3.8 57.5 1.0 CB C:ASP57 3.9 69.3 1.0 OD2 C:ASP85 4.1 67.9 1.0 ND1 C:HIS59 4.1 66.4 1.0 CG C:HIS59 4.2 66.4 1.0 ND2 C:ASN117 4.2 60.4 1.0 ND1 C:HIS241 4.4 57.5 1.0 CE1 C:HIS167 4.5 56.5 1.0 CE1 C:PHE260 4.6 65.8 1.0 C C:HIS241 4.6 57.5 1.0 NE2 C:HIS167 4.8 56.5 1.0 CE1 C:HIS241 4.8 57.5 1.0 OH C:TYR265 4.8 76.7 1.0 CZ C:PHE260 4.8 65.8 1.0 OD1 C:ASN117 4.8 60.4 1.0 NH1 C:ARG89 4.9 72.3 1.0 CA C:ASP85 4.9 67.9 1.0 CA C:HIS241 4.9 57.5 1.0 CA C:ASP57 4.9 69.3 1.0 CG C:ASN117 5.0 60.4 1.0

B.C.Jeong, S.J.Bae, L.Ni, X.Zhang, X.C.Bai, X.Luo. Cryo-Em Structure of the Hippo Signaling Integrator Human Stripak. Nat.Struct.Mol.Biol. 2021.
ISSN: ESSN 1545-9985
PubMed: 33633399
DOI: 10.1038/S41594-021-00564-Y