Manganese in PDB 7cun: The Structure of Human Integrator-PP2A Complex

All present enzymatic activity of The Structure of Human Integrator-PP2A Complex:
3.1.3.16;

The structure of The Structure of Human Integrator-PP2A Complex also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Manganese atom in the The Structure of Human Integrator-PP2A Complex (pdb code 7cun). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the The Structure of Human Integrator-PP2A Complex, PDB code: 7cun:
Jump to Manganese binding site number: 1; 2;

Manganese binding site 1 out of 2 in the The Structure of Human Integrator-PP2A Complex


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of The Structure of Human Integrator-PP2A Complex within 5.0Å range: probe atom residue distance (Å) B Occ Q:Mn501 b:18.5 occ:1.00 NE2 Q:HIS167 2.0 20.1 1.0 ND1 Q:HIS241 2.0 26.1 1.0 OD1 Q:ASN117 2.1 12.1 1.0 CE1 Q:HIS167 2.1 20.1 1.0 OD2 Q:ASP85 2.4 13.1 1.0 CE1 Q:HIS241 2.4 26.1 1.0 CG Q:ASN117 3.0 12.1 1.0 CG Q:ASP85 3.1 13.1 1.0 MN Q:MN502 3.2 29.5 1.0 OD1 Q:ASP85 3.2 13.1 1.0 CD2 Q:HIS167 3.3 20.1 1.0 CG Q:HIS241 3.3 26.1 1.0 ND1 Q:HIS167 3.4 20.1 1.0 ND2 Q:ASN117 3.4 12.1 1.0 NE2 Q:HIS241 3.7 26.1 1.0 CG Q:HIS167 4.0 20.1 1.0 CB Q:HIS241 4.1 26.1 1.0 CA Q:HIS241 4.1 26.1 1.0 CD2 Q:HIS241 4.1 26.1 1.0 CB Q:ASN117 4.2 12.1 1.0 O Q:ALA240 4.3 49.4 1.0 CD2 Q:HIS118 4.3 14.7 1.0 N Q:ASN117 4.4 12.1 1.0 O Q:HIS241 4.5 26.1 1.0 CB Q:ASP85 4.5 13.1 1.0 OD2 Q:ASP57 4.6 12.8 1.0 NE2 Q:HIS118 4.8 14.7 1.0 C Q:HIS241 4.8 26.1 1.0 CA Q:ASN117 4.9 12.1 1.0 O Q:LEU199 4.9 12.9 1.0

Manganese binding site 2 out of 2 in the The Structure of Human Integrator-PP2A Complex


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of The Structure of Human Integrator-PP2A Complex within 5.0Å range: probe atom residue distance (Å) B Occ Q:Mn502 b:29.5 occ:1.00 OD2 Q:ASP85 1.9 13.1 1.0 NE2 Q:HIS59 2.5 14.2 1.0 CE1 Q:HIS59 2.7 14.2 1.0 CG Q:ASP85 3.0 13.1 1.0 MN Q:MN501 3.2 18.5 1.0 OD2 Q:ASP57 3.3 12.8 1.0 NE2 Q:HIS118 3.7 14.7 1.0 CD2 Q:HIS118 3.8 14.7 1.0 CB Q:ASP85 3.9 13.1 1.0 CD2 Q:HIS59 3.9 14.2 1.0 OD1 Q:ASP85 3.9 13.1 1.0 ND1 Q:HIS59 4.0 14.2 1.0 ND1 Q:HIS241 4.2 26.1 1.0 CG Q:ASP57 4.2 12.8 1.0 O Q:HIS241 4.3 26.1 1.0 OD1 Q:ASN117 4.4 12.1 1.0 CE1 Q:HIS167 4.5 20.1 1.0 CE1 Q:HIS241 4.5 26.1 1.0 CG Q:HIS59 4.6 14.2 1.0 OH Q:TYR265 4.7 21.0 1.0 CB Q:ASP57 4.9 12.8 1.0 C Q:HIS241 4.9 26.1 1.0 ND2 Q:ASN117 4.9 12.1 1.0 CA Q:HIS241 4.9 26.1 1.0 OD1 Q:ASP57 5.0 12.8 1.0 CE1 Q:HIS118 5.0 14.7 1.0 NE2 Q:HIS167 5.0 20.1 1.0

H.Zheng, Y.Qi, S.Hu, X.Cao, C.Xu, Z.Yin, X.Chen, Y.Li, W.Liu, J.Li, J.Wang, G.Wei, K.Liang, F.X.Chen, Y.Xu. Identification of Integrator-PP2A Complex (Intac), An Rna Polymerase II Phosphatase. Science V. 370 2020.
ISSN: ESSN 1095-9203
PubMed: 33243860
DOI: 10.1126/SCIENCE.ABB5872