Manganese in PDB 7cec: Structure of ALPHA6BETA1 Integrin in Complex with Laminin-511

The structure of Structure of ALPHA6BETA1 Integrin in Complex with Laminin-511 also contains other interesting chemical elements:

Calcium

(Ca)

4 atoms

The binding sites of Manganese atom in the Structure of ALPHA6BETA1 Integrin in Complex with Laminin-511 (pdb code 7cec). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 3 binding sites of Manganese where determined in the Structure of ALPHA6BETA1 Integrin in Complex with Laminin-511, PDB code: 7cec:
Jump to Manganese binding site number: 1; 2; 3;

Manganese binding site 1 out of 3 in the Structure of ALPHA6BETA1 Integrin in Complex with Laminin-511


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Structure of ALPHA6BETA1 Integrin in Complex with Laminin-511 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mn1001 b:149.5 occ:1.00 OE1 B:GLU169 2.0 122.0 1.0 OD1 B:ASP226 2.0 118.7 1.0 O B:PRO228 2.1 123.8 1.0 OD1 B:ASN224 2.1 105.0 1.0 CD B:GLU169 2.2 122.0 1.0 OE2 B:GLU169 2.3 122.0 1.0 CG B:ASP226 2.6 118.7 1.0 O B:ASP226 2.6 118.7 1.0 OE2 B:GLU229 3.0 125.2 1.0 C B:PRO228 3.2 123.8 1.0 CG B:ASN224 3.3 105.0 1.0 C B:ASP226 3.3 118.7 1.0 CB B:ASP226 3.3 118.7 1.0 OD2 B:ASP226 3.3 118.7 1.0 CG B:GLU169 3.4 122.0 1.0 N B:ASP226 3.5 118.7 1.0 CA B:ASP226 3.6 118.7 1.0 NE2 B:HIS263 3.7 119.7 1.0 CA B:GLU229 3.9 125.2 1.0 CB B:ASN224 3.9 105.0 1.0 N B:GLU229 4.0 125.2 1.0 CD B:GLU229 4.2 125.2 1.0 CB B:GLU169 4.3 122.0 1.0 N B:PRO228 4.3 123.8 1.0 CA B:PRO228 4.3 123.8 1.0 ND2 B:ASN224 4.3 105.0 1.0 C B:SER227 4.3 118.9 1.0 N B:SER227 4.4 118.9 1.0 O B:SER227 4.5 118.9 1.0 CD2 B:HIS263 4.5 119.7 1.0 O B:TYR175 4.5 103.4 1.0 C B:LEU225 4.7 109.4 1.0 CE1 B:HIS263 4.7 119.7 1.0 N B:LEU225 4.8 109.4 1.0 C B:GLU229 4.8 125.2 1.0 CB B:PRO228 4.8 123.8 1.0 CB B:GLU229 4.9 125.2 1.0 CB B:TYR175 4.9 103.4 1.0 CA B:SER227 5.0 118.9 1.0 CG B:GLU229 5.0 125.2 1.0 CD B:PRO228 5.0 123.8 1.0 OE1 E:GLU1607 5.0 127.0 1.0

Manganese binding site 2 out of 3 in the Structure of ALPHA6BETA1 Integrin in Complex with Laminin-511


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Structure of ALPHA6BETA1 Integrin in Complex with Laminin-511 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mn1002 b:164.5 occ:1.00 OE1 B:GLU229 2.0 125.2 1.0 CB B:SER132 2.1 132.1 1.0 OE1 E:GLU1607 2.2 127.0 1.0 OG B:SER132 2.2 132.1 1.0 OE2 E:GLU1607 2.2 127.0 1.0 CD E:GLU1607 2.4 127.0 1.0 OG B:SER134 2.6 127.8 1.0 CD B:GLU229 2.8 125.2 1.0 OE2 B:GLU229 3.4 125.2 1.0 CA B:SER132 3.6 132.1 1.0 CG B:GLU229 3.7 125.2 1.0 OD2 B:ASP130 3.7 129.7 1.0 CG E:GLU1607 3.8 127.0 1.0 CB B:SER134 3.9 127.8 1.0 CB B:ALA260 4.0 136.3 1.0 ND2 B:ASN224 4.1 105.0 1.0 O B:SER227 4.1 118.9 1.0 C B:SER132 4.2 132.1 1.0 N B:SER134 4.2 127.8 1.0 N B:TYR133 4.3 125.1 1.0 N B:SER132 4.6 132.1 1.0 CA B:SER134 4.6 127.8 1.0 CB E:GLU1607 4.6 127.0 1.0 N B:MET135 4.7 135.9 1.0 CG B:ASP130 4.8 129.7 1.0 O B:ASP226 4.9 118.7 1.0 OD1 B:ASN224 4.9 105.0 1.0 O B:SER132 4.9 132.1 1.0 CG B:ASN224 4.9 105.0 1.0 OD1 B:ASP259 5.0 135.2 1.0

Manganese binding site 3 out of 3 in the Structure of ALPHA6BETA1 Integrin in Complex with Laminin-511


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 3 of Structure of ALPHA6BETA1 Integrin in Complex with Laminin-511 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mn1003 b:160.4 occ:1.00 OD2 B:ASP138 2.1 157.9 1.0 O B:SER134 2.4 127.8 1.0 OD2 B:ASP259 2.4 135.2 1.0 OD2 B:ASP137 2.6 160.3 1.0 OD1 B:ASP137 2.8 160.3 1.0 CG B:ASP137 3.0 160.3 1.0 CG B:ASP138 3.0 157.9 1.0 OD1 B:ASP138 3.3 157.9 1.0 CG B:ASP259 3.4 135.2 1.0 C B:SER134 3.6 127.8 1.0 OD1 B:ASP259 4.0 135.2 1.0 N B:ASP138 4.2 157.9 1.0 CA B:MET135 4.3 135.9 1.0 CB B:ASP137 4.3 160.3 1.0 CB B:ASP259 4.3 135.2 1.0 CB B:ASP138 4.3 157.9 1.0 N B:MET135 4.4 135.9 1.0 CA B:SER134 4.6 127.8 1.0 N B:ASP137 4.8 160.3 1.0 C B:MET135 4.8 135.9 1.0 N B:LYS136 4.8 146.9 1.0 CA B:ASP138 4.8 157.9 1.0 CB B:SER134 4.9 127.8 1.0 CA B:ASP137 5.0 160.3 1.0

T.Arimori, N.Miyazaki, M.Takizawa, Y.Taniguchi, C.Cabanas, K.Sekiguchi, J.Takagi. Structural Mechanism of Laminin-511 Recognition By ALPHA6BETA1 Integrin To Be Published.