Manganese in PDB 6s22: Crystal Structure of the Tggalnac-T3 in Complex with Udp, Manganese and FGF23C

The structure of Crystal Structure of the Tggalnac-T3 in Complex with Udp, Manganese and FGF23C, PDB code: 6s22 was solved by M.De Las Rivas, E.J.P.Daniel, Y.Narimatsu, I.Companon, K.Kato, P.Hermosilla, A.Thureau, L.Ceballos-Laita, H.Coelho, P.Bernado, F.Marcelo, L.Hansen, A.Lostao, F.Corzana, H.Clausen, T.A.Gerken, R.Hurtado-Guerrero, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	51.01 / 1.96
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	50.957, 104.823, 143.466, 90.00, 90.00, 90.00
R / Rfree (%)	17.9 / 21.6

The binding sites of Manganese atom in the Crystal Structure of the Tggalnac-T3 in Complex with Udp, Manganese and FGF23C (pdb code 6s22). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Crystal Structure of the Tggalnac-T3 in Complex with Udp, Manganese and FGF23C, PDB code: 6s22:

Manganese binding site 1 out of 1 in the Crystal Structure of the Tggalnac-T3 in Complex with Udp, Manganese and FGF23C


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Crystal Structure of the Tggalnac-T3 in Complex with Udp, Manganese and FGF23C within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn717 b:34.3 occ:1.00 OD2 A:ASP275 2.0 41.1 1.0 NE2 A:HIS277 2.1 27.1 1.0 O3B A:UDP716 2.1 40.6 1.0 O2A A:UDP716 2.1 43.7 1.0 NE2 A:HIS413 2.2 31.1 1.0 O A:HOH963 2.5 39.9 1.0 CE1 A:HIS277 3.0 26.4 1.0 CE1 A:HIS413 3.1 30.6 1.0 CD2 A:HIS277 3.1 30.0 1.0 CD2 A:HIS413 3.2 31.1 1.0 CG A:ASP275 3.2 45.3 1.0 PB A:UDP716 3.4 45.5 1.0 PA A:UDP716 3.5 47.8 1.0 O2B A:UDP716 3.7 40.8 1.0 O3A A:UDP716 3.8 49.9 1.0 CB A:ASP275 3.9 39.0 1.0 ND1 A:HIS277 4.2 28.0 1.0 ND1 A:HIS413 4.3 31.6 1.0 CG A:HIS277 4.3 26.8 1.0 OD1 A:ASP275 4.3 47.0 1.0 CG A:HIS413 4.3 30.2 1.0 O A:VAL414 4.3 32.2 1.0 NH2 A:ARG416 4.4 51.8 1.0 O1A A:UDP716 4.4 54.8 1.0 C5' A:UDP716 4.4 49.2 1.0 O5' A:UDP716 4.5 49.4 1.0 O1B A:UDP716 4.6 48.2 1.0 C3' A:UDP716 4.8 52.5 1.0 O A:HOH918 4.9 41.3 1.0

M.De Las Rivas, E.J.P.Daniel, Y.Narimatsu, I.Companon, K.Kato, P.Hermosilla, A.Thureau, L.Ceballos-Laita, H.Coelho, P.Bernado, F.Marcelo, L.Hansen, A.Lostao, F.Corzana, H.Clausen, T.A.Gerken, R.Hurtado-Guerrero. Molecular Basis For Fibroblast Growth Factor 23 O-Glycosylation By Galnac-T3 Nat.Chem.Biol. 2019.
ISSN: ESSN 1552-4469