Manganese in PDB 6r3j: Aspergillus Niger Ferulic Acid Decarboxylase (Fdc) in Complex with the Covalent Adduct Formed Between Prfmn Cofactor and Crotonic Acid Following Decarboxylation (INT3)

Enzymatic activity of Aspergillus Niger Ferulic Acid Decarboxylase (Fdc) in Complex with the Covalent Adduct Formed Between Prfmn Cofactor and Crotonic Acid Following Decarboxylation (INT3)

All present enzymatic activity of Aspergillus Niger Ferulic Acid Decarboxylase (Fdc) in Complex with the Covalent Adduct Formed Between Prfmn Cofactor and Crotonic Acid Following Decarboxylation (INT3):
4.1.1.102;

Protein crystallography data

The structure of Aspergillus Niger Ferulic Acid Decarboxylase (Fdc) in Complex with the Covalent Adduct Formed Between Prfmn Cofactor and Crotonic Acid Following Decarboxylation (INT3), PDB code: 6r3j was solved by S.S.Bailey, D.Leys, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

*Resolution Low / High (Å)*	87.74 / 1.39
*Space group*	P 2₁ 2₁ 2
*Cell size a, b, c (Å), α, β, γ (°)*	96.028, 63.815, 87.742, 90.00, 90.00, 90.00
*R / R_free (%)*	13.6 / 17.8

Other elements in 6r3j:

The structure of Aspergillus Niger Ferulic Acid Decarboxylase (Fdc) in Complex with the Covalent Adduct Formed Between Prfmn Cofactor and Crotonic Acid Following Decarboxylation (INT3) also contains other interesting chemical elements:

Potassium

(K)

2 atoms

Manganese Binding Sites:

The binding sites of Manganese atom in the Aspergillus Niger Ferulic Acid Decarboxylase (Fdc) in Complex with the Covalent Adduct Formed Between Prfmn Cofactor and Crotonic Acid Following Decarboxylation (INT3) (pdb code 6r3j). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Aspergillus Niger Ferulic Acid Decarboxylase (Fdc) in Complex with the Covalent Adduct Formed Between Prfmn Cofactor and Crotonic Acid Following Decarboxylation (INT3), PDB code: 6r3j:

Manganese binding site 1 out of 1 in 6r3j

Go back to

Manganese Binding Sites List in 6r3j

Manganese binding site 1 out of 1 in the Aspergillus Niger Ferulic Acid Decarboxylase (Fdc) in Complex with the Covalent Adduct Formed Between Prfmn Cofactor and Crotonic Acid Following Decarboxylation (INT3)

Mono view

Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Aspergillus Niger Ferulic Acid Decarboxylase (Fdc) in Complex with the Covalent Adduct Formed Between Prfmn Cofactor and Crotonic Acid Following Decarboxylation (INT3) within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:Mn1102 b:9.1 occ:1.00	OE2	A:GLU233	2.1	8.7	1.0
	OD1	A:ASN168	2.2	8.8	1.0
	O7	A:JRH1101	2.2	9.4	1.0
	O	A:HOH1226	2.2	9.2	1.0
	O	A:HOH1320	2.3	8.6	1.0
	ND1	A:HIS191	2.3	8.4	1.0
	CG	A:ASN168	3.1	7.6	1.0
	CE1	A:HIS191	3.2	9.1	1.0
	CD	A:GLU233	3.2	8.7	1.0
	P1	A:JRH1101	3.4	9.7	1.0
	CG	A:HIS191	3.4	8.5	1.0
	ND2	A:ASN168	3.5	8.4	1.0
	OE1	A:GLU233	3.5	9.4	1.0
	O9	A:JRH1101	3.6	10.0	1.0
	K	A:K1103	3.7	10.0	1.0
	CB	A:HIS191	3.8	9.7	1.0
	O	A:ILE227	4.3	10.0	1.0
	O8	A:JRH1101	4.3	11.9	1.0
	CG1	A:ILE227	4.4	11.1	1.0
	CZ2	A:TRP166	4.4	10.8	1.0
	NE2	A:HIS191	4.4	8.9	1.0
	O6	A:JRH1101	4.5	10.9	1.0
	CB	A:ASN168	4.5	8.4	1.0
	O	A:VAL231	4.5	10.8	1.0
	CD2	A:HIS191	4.5	8.5	1.0
	CG	A:GLU233	4.5	8.9	1.0
	O	A:TRP169	4.6	7.9	1.0
	NE1	A:TRP166	4.6	10.8	1.0
	O	A:PRO228	4.7	9.8	1.0
	CE2	A:TRP166	4.9	9.9	1.0

Reference:

S.S.Bailey, K.A.P.Payne, A.Saaret, S.A.Marshall, I.Gostimskaya, I.Kosov, K.Fisher, S.Hay, D.Leys. Atomic Description of An Enzyme Reaction Dependent on Reversible 1,3-Dipolar Cycloaddition To Be Published.

Page generated: Sun Oct 6 06:58:59 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy