Manganese in PDB 6q99: Ande Virus L Protein N-Terminus Mutant K124A

The structure of Ande Virus L Protein N-Terminus Mutant K124A, PDB code: 6q99 was solved by Y.Fernandez-Garcia, T.Holm, J.Kirchmair, S.Wurr, S.Gunther, S.Reindl, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	79.60 / 2.95
Space group	P 4 21 2
Cell size a, b, c (Å), α, β, γ (°)	82.341, 82.341, 79.599, 90.00, 90.00, 90.00
R / Rfree (%)	23.8 / 31.3

The binding sites of Manganese atom in the Ande Virus L Protein N-Terminus Mutant K124A (pdb code 6q99). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Ande Virus L Protein N-Terminus Mutant K124A, PDB code: 6q99:
Jump to Manganese binding site number: 1; 2;

Manganese binding site 1 out of 2 in the Ande Virus L Protein N-Terminus Mutant K124A


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Ande Virus L Protein N-Terminus Mutant K124A within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn301 b:45.0 occ:1.00 OD2 A:ASP97 2.5 19.1 1.0 O A:VAL111 2.5 21.8 1.0 NE2 A:HIS36 3.2 20.9 1.0 OE1 A:GLU110 3.2 24.0 1.0 CD A:GLU110 3.4 27.4 1.0 CE1 A:HIS36 3.5 21.1 1.0 CG A:ASP97 3.5 19.1 1.0 C A:VAL111 3.7 19.9 1.0 MN A:MN3302 3.8 0.6 1.0 OE2 A:GLU110 3.8 28.7 1.0 CG A:GLU110 3.9 18.4 1.0 OD1 A:ASP97 3.9 19.6 1.0 CD2 A:HIS36 3.9 29.4 1.0 ND1 A:HIS36 4.3 22.0 1.0 N A:VAL111 4.4 18.7 1.0 CG A:HIS36 4.6 22.5 1.0 N A:THR112 4.6 20.3 1.0 CA A:VAL111 4.6 19.3 1.0 CA A:THR112 4.7 21.2 1.0 CB A:ASP97 4.9 18.5 1.0 CB A:THR112 4.9 21.1 1.0

Manganese binding site 2 out of 2 in the Ande Virus L Protein N-Terminus Mutant K124A


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Ande Virus L Protein N-Terminus Mutant K124A within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn302 b:0.6 occ:1.00 OD1 A:ASP97 2.4 19.6 1.0 OE1 A:GLU54 2.6 44.5 1.0 CG A:ASP97 3.0 19.1 1.0 OD2 A:ASP97 3.3 19.1 1.0 O A:THR95 3.6 22.3 1.0 CD A:GLU54 3.7 45.2 1.0 MN A:MN3301 3.8 45.0 1.0 CB A:ASP97 4.3 18.5 1.0 N A:ASP97 4.3 22.4 1.0 CA A:ASP97 4.4 18.1 1.0 OE1 A:GLU110 4.4 24.0 1.0 OE2 A:GLU110 4.5 28.7 1.0 OE2 A:GLU54 4.5 52.8 1.0 C A:PRO96 4.5 17.6 1.0 CG A:GLU54 4.7 44.8 1.0 C A:THR95 4.7 18.1 1.0 CE1 A:HIS36 4.7 21.1 1.0 CD A:GLU110 4.8 27.4 1.0 CB A:GLU54 4.8 36.9 1.0 O A:PRO96 4.9 20.8 1.0 CA A:PRO96 5.0 17.4 1.0

Y.Fernandez-Garcia, J.Kirchmair, T.Holm, S.Wurr, S.Gunther, S.Reindl. Specific Inhibition of A Diverse Set of Segmented Negative Strand Viruses By A Single Molecule To Be Published.