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Manganese in PDB 6q92: Crystal Structure of Human Arginase-1 at pH 7.0 in Complex with Abh
Enzymatic activity of Crystal Structure of Human Arginase-1 at pH 7.0 in Complex with Abh
All present enzymatic activity of Crystal Structure of Human Arginase-1 at pH 7.0 in Complex with Abh:
3.5.3.1;
3.5.3.1;
Protein crystallography data
The structure of Crystal Structure of Human Arginase-1 at pH 7.0 in Complex with Abh, PDB code: 6q92
was solved by
Y.Grobben,
J.C.M.Uitdehaag,
G.J.R.Zaman,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 39.14 / 1.50 |
| Space group | P 3 |
| Cell size a, b, c (Å), α, β, γ (°) | 90.380, 90.380, 69.254, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 13.5 / 14.7 |
Other elements in 6q92:
The structure of Crystal Structure of Human Arginase-1 at pH 7.0 in Complex with Abh also contains other interesting chemical elements:
| Sodium | (Na) | 2 atoms |
Manganese Binding Sites:
The binding sites of Manganese atom in the Crystal Structure of Human Arginase-1 at pH 7.0 in Complex with Abh
(pdb code 6q92). This binding sites where shown within
5.0 Angstroms radius around Manganese atom.
In total 4 binding sites of Manganese where determined in the Crystal Structure of Human Arginase-1 at pH 7.0 in Complex with Abh, PDB code: 6q92:
Jump to Manganese binding site number: 1; 2; 3; 4;
In total 4 binding sites of Manganese where determined in the Crystal Structure of Human Arginase-1 at pH 7.0 in Complex with Abh, PDB code: 6q92:
Jump to Manganese binding site number: 1; 2; 3; 4;
Manganese binding site 1 out of 4 in 6q92
Go back to
Manganese Binding Sites List in 6q92
Manganese binding site 1 out
of 4 in the Crystal Structure of Human Arginase-1 at pH 7.0 in Complex with Abh
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 1 of Crystal Structure of Human Arginase-1 at pH 7.0 in Complex with Abh within 5.0Å range:
|
Manganese binding site 2 out of 4 in 6q92
Go back to
Manganese Binding Sites List in 6q92
Manganese binding site 2 out
of 4 in the Crystal Structure of Human Arginase-1 at pH 7.0 in Complex with Abh
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 2 of Crystal Structure of Human Arginase-1 at pH 7.0 in Complex with Abh within 5.0Å range:
|
Manganese binding site 3 out of 4 in 6q92
Go back to
Manganese Binding Sites List in 6q92
Manganese binding site 3 out
of 4 in the Crystal Structure of Human Arginase-1 at pH 7.0 in Complex with Abh
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 3 of Crystal Structure of Human Arginase-1 at pH 7.0 in Complex with Abh within 5.0Å range:
|
Manganese binding site 4 out of 4 in 6q92
Go back to
Manganese Binding Sites List in 6q92
Manganese binding site 4 out
of 4 in the Crystal Structure of Human Arginase-1 at pH 7.0 in Complex with Abh
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 4 of Crystal Structure of Human Arginase-1 at pH 7.0 in Complex with Abh within 5.0Å range:
|
Reference:
Y.Grobben,
J.C.M.Uitdehaag,
G.J.R.Zaman.
Structural Insights Into Human Arginase-1 pH Dependence and Its Inhibition By the Small Molecule Inhibitor Cb-1158 J.Struct.Biol. 2019.
ISSN: ESSN 1095-8657
DOI: 10.1016/J.YJSBX.2019.100014
Page generated: Sun Oct 6 05:54:44 2024
ISSN: ESSN 1095-8657
DOI: 10.1016/J.YJSBX.2019.100014
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