Manganese in PDB 6q4v: Klentaq Dna Polymerase in Complex with Datp

All present enzymatic activity of Klentaq Dna Polymerase in Complex with Datp:
2.7.7.7;

The structure of Klentaq Dna Polymerase in Complex with Datp, PDB code: 6q4v was solved by H.M.Kropp, K.Diederichs, A.Marx, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.41 / 2.01
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	109.482, 109.482, 91.255, 90.00, 90.00, 120.00
R / Rfree (%)	18.6 / 21.9

The structure of Klentaq Dna Polymerase in Complex with Datp also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Manganese atom in the Klentaq Dna Polymerase in Complex with Datp (pdb code 6q4v). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Klentaq Dna Polymerase in Complex with Datp, PDB code: 6q4v:

Manganese binding site 1 out of 1 in the Klentaq Dna Polymerase in Complex with Datp


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Klentaq Dna Polymerase in Complex with Datp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn903 b:46.6 occ:1.00 OD2 A:ASP785 2.0 54.6 1.0 O1B A:DTP901 2.1 44.1 1.0 OD1 A:ASP610 2.2 63.7 1.0 O1G A:DTP901 2.2 42.9 1.0 O A:TYR611 2.2 66.3 1.0 O1A A:DTP901 2.2 45.7 1.0 CG A:ASP785 3.1 46.0 1.0 PB A:DTP901 3.2 42.0 1.0 CG A:ASP610 3.3 53.7 1.0 H5'2 A:DTP901 3.3 54.8 1.0 C A:TYR611 3.4 57.2 1.0 PA A:DTP901 3.4 44.1 1.0 PG A:DTP901 3.4 46.5 1.0 MG A:MG902 3.6 39.1 1.0 OD1 A:ASP785 3.6 51.7 1.0 O3A A:DTP901 3.6 44.3 1.0 O3B A:DTP901 3.6 43.8 1.0 OD2 A:ASP610 3.7 59.9 1.0 O A:HOH1023 3.7 34.9 1.0 H A:ILE614 4.0 55.0 1.0 HB2 A:TYR611 4.0 64.2 1.0 N A:TYR611 4.0 51.0 1.0 HA A:SER612 4.0 68.5 1.0 H A:GLN613 4.0 60.2 1.0 H A:TYR611 4.1 61.2 1.0 HG22 A:ILE614 4.1 49.8 1.0 O A:HOH1115 4.1 39.4 1.0 HB A:ILE614 4.1 53.0 1.0 CA A:TYR611 4.2 55.5 1.0 C5' A:DTP901 4.2 45.7 1.0 O5' A:DTP901 4.3 41.9 1.0 HG21 A:ILE614 4.3 49.8 1.0 HB2 A:ASP785 4.4 48.7 1.0 O2G A:DTP901 4.4 46.3 1.0 N A:SER612 4.4 57.5 1.0 C A:ASP610 4.4 46.4 1.0 CB A:ASP785 4.4 40.6 1.0 N A:GLN613 4.5 50.2 1.0 O3G A:DTP901 4.5 42.0 1.0 CB A:TYR611 4.5 53.5 1.0 CB A:ASP610 4.5 50.8 1.0 CA A:SER612 4.6 57.0 1.0 O2B A:DTP901 4.6 41.9 1.0 CG2 A:ILE614 4.6 41.5 1.0 H5'1 A:DTP901 4.6 54.8 1.0 O2A A:DTP901 4.6 39.3 1.0 HB3 A:TYR611 4.7 64.2 1.0 N A:ILE614 4.7 45.9 1.0 C A:SER612 4.7 54.9 1.0 HZ3 A:LYS663 4.8 75.6 1.0 HB3 A:ASP610 4.8 60.9 1.0 HB3 A:ASP785 4.8 48.7 1.0 O A:ASP610 4.8 46.8 1.0 CB A:ILE614 4.8 44.2 1.0 O A:ASP785 4.8 40.5 1.0 HA A:ASP610 4.9 50.9 1.0 CA A:ASP610 4.9 42.5 1.0 O A:HOH1057 4.9 43.0 1.0

H.M.Kropp, K.Diederichs, A.Marx. The Structure of An Archaeal B-Family Dna Polymerase in Complex with A Chemically Modified Nucleotide. Angew.Chem.Int.Ed.Engl. V. 58 5457 2019.
ISSN: ESSN 1521-3773
PubMed: 30761722
DOI: 10.1002/ANIE.201900315