Atomistry » Manganese » PDB 6m30-6obu » 6obr
Atomistry »
  Manganese »
    PDB 6m30-6obu »
      6obr »

Manganese in PDB 6obr: PP1 Y134A in Complex with Microcystin Lr

Enzymatic activity of PP1 Y134A in Complex with Microcystin Lr

All present enzymatic activity of PP1 Y134A in Complex with Microcystin Lr:
3.1.3.16;

Protein crystallography data

The structure of PP1 Y134A in Complex with Microcystin Lr, PDB code: 6obr was solved by M.S.Choy, T.M.Moon, J.A.Bray, T.L.Archuleta, W.Shi, W.Peti, R.Page, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 38.28 / 1.50
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 64.932, 76.550, 131.213, 90.00, 90.00, 90.00
R / Rfree (%) 18.8 / 21

Other elements in 6obr:

The structure of PP1 Y134A in Complex with Microcystin Lr also contains other interesting chemical elements:

Chlorine (Cl) 2 atoms

Manganese Binding Sites:

The binding sites of Manganese atom in the PP1 Y134A in Complex with Microcystin Lr (pdb code 6obr). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 4 binding sites of Manganese where determined in the PP1 Y134A in Complex with Microcystin Lr, PDB code: 6obr:
Jump to Manganese binding site number: 1; 2; 3; 4;

Manganese binding site 1 out of 4 in 6obr

Go back to Manganese Binding Sites List in 6obr
Manganese binding site 1 out of 4 in the PP1 Y134A in Complex with Microcystin Lr


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of PP1 Y134A in Complex with Microcystin Lr within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mn401

b:22.2
occ:1.00
OD1 A:ASN124 2.0 22.5 1.0
O A:HOH574 2.1 28.1 1.0
NE2 A:HIS173 2.1 17.6 1.0
ND1 A:HIS248 2.3 22.4 1.0
OD2 A:ASP92 2.3 21.1 1.0
CE1 A:HIS248 3.1 22.8 1.0
CD2 A:HIS173 3.1 19.5 1.0
CG A:ASN124 3.1 19.3 1.0
CE1 A:HIS173 3.1 23.1 1.0
CG A:ASP92 3.1 18.4 1.0
MN A:MN402 3.3 22.6 1.0
O D:HOH102 3.3 26.1 1.0
CG A:HIS248 3.4 22.9 1.0
OD1 A:ASP92 3.4 19.1 1.0
CA A:HIS248 3.6 20.9 1.0
ND2 A:ASN124 3.7 22.5 1.0
CB A:HIS248 3.8 23.8 1.0
O A:HIS248 4.0 27.8 1.0
OD2 A:ASP64 4.0 22.9 1.0
CD2 A:HIS125 4.2 23.4 1.0
ND1 A:HIS173 4.2 20.8 1.0
CG A:HIS173 4.2 18.1 1.0
NE2 A:HIS248 4.3 24.9 1.0
C A:HIS248 4.3 28.6 1.0
CB A:ASN124 4.3 20.8 1.0
N A:ASN124 4.4 19.4 1.0
CB A:ASP92 4.4 18.6 1.0
CD2 A:HIS248 4.4 24.3 1.0
O A:LEU205 4.6 23.6 1.0
N A:HIS248 4.7 24.9 1.0
NE2 A:HIS125 4.7 25.9 1.0
CG A:ASP64 4.9 22.5 1.0
CA A:ASN124 4.9 20.4 1.0
O D:HOH101 4.9 26.5 1.0
OD1 A:ASP64 5.0 22.4 1.0

Manganese binding site 2 out of 4 in 6obr

Go back to Manganese Binding Sites List in 6obr
Manganese binding site 2 out of 4 in the PP1 Y134A in Complex with Microcystin Lr


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of PP1 Y134A in Complex with Microcystin Lr within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mn402

b:22.6
occ:1.00
OD2 A:ASP64 2.1 22.9 1.0
O A:HOH574 2.1 28.1 1.0
O D:HOH101 2.2 26.5 1.0
NE2 A:HIS66 2.2 23.2 1.0
OD2 A:ASP92 2.2 21.1 1.0
CE1 A:HIS66 3.1 22.7 1.0
CD2 A:HIS66 3.2 19.4 1.0
CG A:ASP64 3.2 22.5 1.0
CG A:ASP92 3.3 18.4 1.0
MN A:MN401 3.3 22.2 1.0
CB A:ASP92 3.6 18.6 1.0
O D:HOH102 3.8 26.1 1.0
CB A:ASP64 3.9 19.9 1.0
OXT D:FGA6 4.1 46.6 1.0
OD1 A:ASP64 4.1 22.4 1.0
O A:HIS248 4.1 27.8 1.0
CD2 A:HIS125 4.2 23.4 1.0
CE1 A:PHE267 4.3 24.2 1.0
ND1 A:HIS66 4.3 22.7 1.0
CG A:HIS66 4.3 19.3 1.0
NE2 A:HIS125 4.3 25.9 1.0
OD1 A:ASP92 4.4 19.1 1.0
NE2 A:HIS173 4.5 17.6 1.0
O D:FGA6 4.5 43.9 1.0
CE1 A:HIS173 4.6 23.1 1.0
CA A:HIS248 4.6 20.9 1.0
C A:HIS248 4.6 28.6 1.0
OH A:TYR272 4.6 30.2 1.0
C D:FGA6 4.7 43.8 1.0
OD1 A:ASN124 4.7 22.5 1.0
CZ A:PHE267 4.9 23.5 1.0
ND1 A:HIS248 4.9 22.4 1.0

Manganese binding site 3 out of 4 in 6obr

Go back to Manganese Binding Sites List in 6obr
Manganese binding site 3 out of 4 in the PP1 Y134A in Complex with Microcystin Lr


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 3 of PP1 Y134A in Complex with Microcystin Lr within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mn401

b:23.1
occ:1.00
O B:HOH533 2.0 26.0 1.0
OD1 B:ASN124 2.2 20.7 1.0
NE2 B:HIS173 2.2 25.3 1.0
ND1 B:HIS248 2.2 24.1 1.0
OD2 B:ASP92 2.2 20.3 1.0
O B:HOH596 3.0 24.3 1.0
CE1 B:HIS248 3.0 25.2 1.0
CG B:ASP92 3.1 18.7 1.0
CD2 B:HIS173 3.1 19.0 1.0
CE1 B:HIS173 3.2 22.7 1.0
CG B:ASN124 3.2 21.7 1.0
MN B:MN402 3.3 23.3 1.0
CG B:HIS248 3.3 27.3 1.0
OD1 B:ASP92 3.4 20.1 1.0
CA B:HIS248 3.6 26.6 1.0
ND2 B:ASN124 3.8 22.4 1.0
CB B:HIS248 3.8 25.3 1.0
O B:HIS248 4.0 27.4 1.0
OD2 B:ASP64 4.0 22.6 1.0
NE2 B:HIS248 4.2 25.2 1.0
CD2 B:HIS125 4.2 20.8 1.0
ND1 B:HIS173 4.3 22.8 1.0
CG B:HIS173 4.3 22.4 1.0
C B:HIS248 4.3 27.5 1.0
N B:ASN124 4.4 22.3 1.0
CD2 B:HIS248 4.4 28.3 1.0
CB B:ASP92 4.4 18.9 1.0
CB B:ASN124 4.4 21.7 1.0
N B:HIS248 4.6 24.3 1.0
O B:LEU205 4.6 24.3 1.0
CG B:ASP64 4.8 25.6 1.0
NE2 B:HIS125 4.8 23.4 1.0
CA B:ASN124 4.9 18.6 1.0
O E:HOH101 4.9 30.8 1.0
OD1 B:ASP64 4.9 23.9 1.0

Manganese binding site 4 out of 4 in 6obr

Go back to Manganese Binding Sites List in 6obr
Manganese binding site 4 out of 4 in the PP1 Y134A in Complex with Microcystin Lr


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 4 of PP1 Y134A in Complex with Microcystin Lr within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mn402

b:23.3
occ:1.00
OD2 B:ASP64 2.1 22.6 1.0
O B:HOH533 2.1 26.0 1.0
O E:HOH101 2.1 30.8 1.0
OD2 B:ASP92 2.2 20.3 1.0
NE2 B:HIS66 2.2 20.9 1.0
CE1 B:HIS66 3.2 20.2 1.0
CG B:ASP92 3.2 18.7 1.0
CD2 B:HIS66 3.2 22.1 1.0
CG B:ASP64 3.2 25.6 1.0
MN B:MN401 3.3 23.1 1.0
CB B:ASP92 3.6 18.9 1.0
O B:HOH596 3.7 24.3 1.0
CB B:ASP64 3.9 23.5 1.0
O E:FGA6 4.1 39.8 1.0
OD1 B:ASP64 4.1 23.9 1.0
O B:HIS248 4.2 27.4 1.0
CD2 B:HIS125 4.2 20.8 1.0
ND1 B:HIS66 4.3 20.4 1.0
OD1 B:ASP92 4.3 20.1 1.0
CE1 B:PHE267 4.3 24.9 1.0
NE2 B:HIS125 4.3 23.4 1.0
CG B:HIS66 4.3 21.9 1.0
OH B:TYR272 4.5 34.3 1.0
NE2 B:HIS173 4.5 25.3 1.0
CA B:HIS248 4.6 26.6 1.0
OXT E:FGA6 4.6 39.0 1.0
CE1 B:HIS173 4.6 22.7 1.0
C B:HIS248 4.6 27.5 1.0
C E:FGA6 4.7 36.6 1.0
OD1 B:ASN124 4.8 20.7 1.0
ND1 B:HIS248 4.9 24.1 1.0
CZ B:PHE267 4.9 23.5 1.0

Reference:

M.S.Choy, T.M.Moon, R.Ravindran, J.A.Bray, L.C.Robinson, T.L.Archuleta, W.Shi, W.Peti, K.Tatchell, R.Page. SDS22 Selectively Recognizes and Traps Metal-Deficient Inactive PP1. Proc.Natl.Acad.Sci.Usa V. 116 20472 2019.
ISSN: ESSN 1091-6490
PubMed: 31548429
DOI: 10.1073/PNAS.1908718116
Page generated: Tue Dec 15 04:58:11 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy