Manganese in PDB 6j5x: Crystal Structure of Fumarylpyruvate Hydrolase From Corynebacterium Glutamicum in Complex with MN2+ and Pyruvate

The structure of Crystal Structure of Fumarylpyruvate Hydrolase From Corynebacterium Glutamicum in Complex with MN2+ and Pyruvate, PDB code: 6j5x was solved by H.Hong, H.Seo, K.-J.Kim, W.Park, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.72 / 1.79
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	66.621, 71.296, 112.260, 90.00, 90.00, 90.00
R / Rfree (%)	18.6 / 22.7

The binding sites of Manganese atom in the Crystal Structure of Fumarylpyruvate Hydrolase From Corynebacterium Glutamicum in Complex with MN2+ and Pyruvate (pdb code 6j5x). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Crystal Structure of Fumarylpyruvate Hydrolase From Corynebacterium Glutamicum in Complex with MN2+ and Pyruvate, PDB code: 6j5x:
Jump to Manganese binding site number: 1; 2;

Manganese binding site 1 out of 2 in the Crystal Structure of Fumarylpyruvate Hydrolase From Corynebacterium Glutamicum in Complex with MN2+ and Pyruvate


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Crystal Structure of Fumarylpyruvate Hydrolase From Corynebacterium Glutamicum in Complex with MN2+ and Pyruvate within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn305 b:27.2 occ:1.00 OE2 A:GLU124 2.1 22.5 1.0 O A:HOH482 2.1 30.5 1.0 OE1 A:GLU122 2.2 27.7 1.0 OD2 A:ASP153 2.2 21.5 1.0 O A:HOH415 2.3 23.9 1.0 CD A:GLU124 3.1 21.0 1.0 CG A:ASP153 3.2 21.0 1.0 CD A:GLU122 3.4 27.4 1.0 CB A:ASP153 3.5 21.7 1.0 OE1 A:GLU124 3.5 20.3 1.0 NZ A:LYS174 3.6 21.4 1.0 O A:VAL73 3.9 21.5 1.0 CZ A:PHE95 4.0 18.8 1.0 CB A:GLU122 4.1 24.1 1.0 OE2 A:GLU122 4.2 29.9 1.0 CG A:GLU122 4.3 24.5 1.0 O A:HOH458 4.3 37.4 1.0 OD1 A:ASP153 4.4 20.5 1.0 CG A:GLU124 4.4 22.6 1.0 CB A:THR242 4.7 28.0 1.0 CE A:LYS174 4.7 19.9 1.0 N A:THR242 4.7 24.2 1.0 CA A:GLY241 4.7 21.8 1.0 CG2 A:THR242 4.7 26.6 1.0 CE1 A:PHE95 4.8 19.1 1.0 CA A:ASP153 4.9 19.1 1.0 O A:ASP153 4.9 20.4 1.0 C A:GLY241 4.9 22.9 1.0 CE2 A:PHE95 5.0 18.9 1.0

Manganese binding site 2 out of 2 in the Crystal Structure of Fumarylpyruvate Hydrolase From Corynebacterium Glutamicum in Complex with MN2+ and Pyruvate


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Crystal Structure of Fumarylpyruvate Hydrolase From Corynebacterium Glutamicum in Complex with MN2+ and Pyruvate within 5.0Å range: probe atom residue distance (Å) B Occ B:Mn304 b:22.6 occ:1.00 OE2 B:GLU124 1.9 18.4 1.0 O3 B:PYR305 2.1 25.0 1.0 OD2 B:ASP153 2.1 19.5 1.0 OE1 B:GLU122 2.2 23.7 1.0 O B:HOH428 2.3 19.8 1.0 O1 B:PYR305 2.3 21.1 1.0 C2 B:PYR305 2.9 24.5 1.0 C1 B:PYR305 3.0 26.5 1.0 CD B:GLU124 3.0 17.8 1.0 CG B:ASP153 3.1 19.5 1.0 CD B:GLU122 3.4 25.4 1.0 CB B:ASP153 3.5 18.9 1.0 OE1 B:GLU124 3.5 19.6 1.0 NZ B:LYS174 3.8 19.0 1.0 OE2 B:GLU122 4.2 27.5 1.0 CB B:GLU122 4.2 23.5 1.0 O2 B:PYR305 4.3 25.4 1.0 O B:VAL73 4.3 24.8 1.0 CZ B:PHE95 4.3 16.9 1.0 OD1 B:ASP153 4.3 18.1 1.0 CG B:GLU124 4.3 18.4 1.0 N B:THR242 4.3 19.8 1.0 C3 B:PYR305 4.4 25.9 1.0 CG B:GLU122 4.4 22.6 1.0 CB B:THR242 4.5 20.2 1.0 CG2 B:THR242 4.5 21.4 1.0 CA B:GLY241 4.6 21.7 1.0 CE B:LYS174 4.7 18.2 1.0 O B:HOH431 4.8 37.6 1.0 C B:GLY241 4.8 20.5 1.0 CE1 B:PHE95 4.9 16.1 1.0 CA B:ASP153 4.9 18.7 1.0

H.Hong, H.Seo, W.Park, K.-J.Kim. Sequence, Structure and Function-Based Classification of the Broadly Conserved Fah Superfamily Reveals Two Distinct Fumarylpyruvate Hydrolase Subfamilies. Environ.Microbiol. 2019.
ISSN: ESSN 1462-2920
PubMed: 31657110
DOI: 10.1111/1462-2920.14844