Manganese in PDB 6i9n: Jmjc Domain-Containing Protein 5 (JMJD5) in Complex with Mn and L-2- Hydroxyglutarate

All present enzymatic activity of Jmjc Domain-Containing Protein 5 (JMJD5) in Complex with Mn and L-2- Hydroxyglutarate:
1.14.11.27;

The structure of Jmjc Domain-Containing Protein 5 (JMJD5) in Complex with Mn and L-2- Hydroxyglutarate, PDB code: 6i9n was solved by R.Chowdhury, M.S.Islam, C.J.Schofield, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.81 / 1.36
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	49.642, 64.428, 77.543, 90.00, 90.00, 90.00
R / Rfree (%)	15 / 15.9

The binding sites of Manganese atom in the Jmjc Domain-Containing Protein 5 (JMJD5) in Complex with Mn and L-2- Hydroxyglutarate (pdb code 6i9n). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Jmjc Domain-Containing Protein 5 (JMJD5) in Complex with Mn and L-2- Hydroxyglutarate, PDB code: 6i9n:

Manganese binding site 1 out of 1 in the Jmjc Domain-Containing Protein 5 (JMJD5) in Complex with Mn and L-2- Hydroxyglutarate


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Jmjc Domain-Containing Protein 5 (JMJD5) in Complex with Mn and L-2- Hydroxyglutarate within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn501 b:11.7 occ:1.00 OD2 A:ASP323 2.1 13.5 1.0 O2 A:S2G502 2.1 12.9 1.0 O3 A:S2G502 2.2 12.9 1.0 NE2 A:HIS321 2.2 12.3 1.0 O A:HOH697 2.3 14.5 1.0 NE2 A:HIS400 2.3 12.4 1.0 HO3 A:S2G502 2.5 15.4 1.0 C1 A:S2G502 2.9 12.7 1.0 C2 A:S2G502 3.0 14.9 1.0 CG A:ASP323 3.1 14.0 1.0 CE1 A:HIS321 3.1 13.1 1.0 CE1 A:HIS400 3.2 10.7 1.0 CD2 A:HIS321 3.2 11.4 1.0 HE1 A:HIS321 3.3 15.8 1.0 HE1 A:HIS400 3.3 12.8 1.0 CD2 A:HIS400 3.3 12.2 1.0 H2 A:S2G502 3.4 17.8 1.0 HD2 A:HIS321 3.4 13.7 1.0 OD1 A:ASP323 3.5 16.3 1.0 HD2 A:HIS400 3.5 14.7 1.0 HZ2 A:TRP414 3.7 17.7 1.0 O A:HOH703 3.9 17.8 1.0 O A:HOH758 4.1 27.1 1.0 O1 A:S2G502 4.1 14.1 1.0 HE1 A:TRP414 4.2 17.8 1.0 HD22 A:ASN327 4.3 14.8 1.0 ND1 A:HIS321 4.3 12.2 1.0 ND1 A:HIS400 4.3 10.8 1.0 CG A:HIS321 4.4 11.7 1.0 O A:HOH756 4.4 23.8 1.0 C3 A:S2G502 4.4 12.8 1.0 CG A:HIS400 4.4 10.3 1.0 CZ2 A:TRP414 4.5 14.7 1.0 CB A:ASP323 4.5 12.8 1.0 H3A A:S2G502 4.5 15.3 1.0 HB2 A:ASP323 4.5 15.3 1.0 HD21 A:ASN327 4.7 14.8 1.0 HH2 A:TRP310 4.7 20.8 1.0 NE1 A:TRP414 4.7 14.8 1.0 ND2 A:ASN327 4.8 12.3 1.0 H4A A:S2G502 4.8 15.7 1.0 H4 A:S2G502 4.9 15.7 1.0 CE2 A:TRP414 5.0 12.9 1.0 HZ2 A:TRP310 5.0 19.1 1.0

S.Islam, C.J.Schofield, R.Chowdhury. Jmjc Domain-Containing Protein 5 (JMJD5) in Complex with Mn and L-2-Hydroxyglutarate To Be Published.