Manganese in PDB 6fbg: Klentaq Dna Polymerase Processing A Modified Primer - Bearing the Modification Upstream at the Fifth Primer Nucleotide.

All present enzymatic activity of Klentaq Dna Polymerase Processing A Modified Primer - Bearing the Modification Upstream at the Fifth Primer Nucleotide.:
2.7.7.7;

The structure of Klentaq Dna Polymerase Processing A Modified Primer - Bearing the Modification Upstream at the Fifth Primer Nucleotide., PDB code: 6fbg was solved by H.M.Kropp, K.Diederichs, A.Marx, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.32 / 1.70
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	109.288, 109.288, 90.723, 90.00, 90.00, 120.00
R / Rfree (%)	19.5 / 21.7

The binding sites of Manganese atom in the Klentaq Dna Polymerase Processing A Modified Primer - Bearing the Modification Upstream at the Fifth Primer Nucleotide. (pdb code 6fbg). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Klentaq Dna Polymerase Processing A Modified Primer - Bearing the Modification Upstream at the Fifth Primer Nucleotide., PDB code: 6fbg:
Jump to Manganese binding site number: 1; 2;

Manganese binding site 1 out of 2 in the Klentaq Dna Polymerase Processing A Modified Primer - Bearing the Modification Upstream at the Fifth Primer Nucleotide.


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Klentaq Dna Polymerase Processing A Modified Primer - Bearing the Modification Upstream at the Fifth Primer Nucleotide. within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn901 b:31.5 occ:1.00 O3G A:XG4907 2.1 29.4 1.0 O A:TYR611 2.1 39.4 1.0 OD1 A:ASP610 2.1 36.8 1.0 OD2 A:ASP785 2.1 34.2 1.0 O1B A:XG4907 2.2 30.9 1.0 O1A A:XG4907 2.4 30.6 1.0 PB A:XG4907 3.2 32.4 1.0 H5' A:XG4907 3.2 36.6 1.0 CG A:ASP785 3.2 28.9 1.0 CG A:ASP610 3.2 31.6 1.0 C A:TYR611 3.3 36.8 1.0 PA A:XG4907 3.4 31.9 1.0 PG A:XG4907 3.4 34.2 1.0 N3A A:XG4907 3.5 32.5 1.0 O3B A:XG4907 3.6 34.3 1.0 OD1 A:ASP785 3.6 33.0 1.0 MN A:MN902 3.6 25.9 0.8 OD2 A:ASP610 3.6 36.8 1.0 O A:HOH1092 3.7 32.9 1.0 H A:GLN613 3.8 45.1 1.0 HA A:SER612 3.9 46.6 1.0 HG22 A:ILE614 3.9 41.6 1.0 O A:HOH1155 4.0 43.4 1.0 H A:ILE614 4.0 39.4 1.0 N A:TYR611 4.1 29.6 1.0 C5' A:XG4907 4.1 30.4 1.0 H A:TYR611 4.1 35.5 1.0 HB2 A:TYR611 4.2 37.6 1.0 CA A:TYR611 4.2 32.2 1.0 O5' A:XG4907 4.3 28.9 1.0 N A:GLN613 4.3 37.6 1.0 N A:SER612 4.3 37.7 1.0 O1G A:XG4907 4.3 35.9 1.0 HB A:ILE614 4.3 41.3 1.0 C A:ASP610 4.4 28.1 1.0 O2G A:XG4907 4.4 31.4 1.0 H5'A A:XG4907 4.4 36.6 1.0 CA A:SER612 4.4 38.9 1.0 HN3A A:XG4907 4.4 39.0 1.0 CB A:ASP610 4.5 29.7 1.0 CB A:ASP785 4.5 27.4 1.0 HB2 A:ASP785 4.5 32.9 1.0 O2B A:XG4907 4.6 30.7 1.0 HG21 A:ILE614 4.6 41.6 1.0 C A:SER612 4.6 35.8 1.0 CG2 A:ILE614 4.6 34.7 1.0 CB A:TYR611 4.6 31.3 1.0 O2A A:XG4907 4.6 29.2 1.0 HB3 A:ASP610 4.7 35.7 1.0 O A:ASP610 4.7 32.6 1.0 N A:ILE614 4.8 32.8 1.0 HB3 A:TYR611 4.8 37.6 1.0 O A:HOH1108 4.9 33.6 1.0 CA A:ASP610 4.9 28.0 1.0 HB3 A:ASP785 4.9 32.9 1.0 O A:ASP785 4.9 29.2 1.0 HA A:ASP610 4.9 33.7 1.0 CB A:ILE614 5.0 34.4 1.0 O3' B:DC112 5.0 34.7 1.0

Manganese binding site 2 out of 2 in the Klentaq Dna Polymerase Processing A Modified Primer - Bearing the Modification Upstream at the Fifth Primer Nucleotide.


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Klentaq Dna Polymerase Processing A Modified Primer - Bearing the Modification Upstream at the Fifth Primer Nucleotide. within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn902 b:25.9 occ:0.79 OD1 A:ASP785 2.1 33.0 1.0 OD2 A:ASP610 2.2 36.8 1.0 O A:HOH1023 2.2 29.4 1.0 O1A A:XG4907 2.2 30.6 1.0 O A:HOH1108 2.2 33.6 1.0 O3' B:DC112 2.2 34.7 1.0 CG A:ASP610 3.1 31.6 1.0 CG A:ASP785 3.1 28.9 1.0 PA A:XG4907 3.4 31.9 1.0 C3' B:DC112 3.4 35.0 1.0 OD1 A:ASP610 3.4 36.8 1.0 OD2 A:ASP785 3.4 34.2 1.0 HB2 A:GLU786 3.5 41.8 1.0 H3' B:DC112 3.5 42.0 1.0 MN A:MN901 3.6 31.5 1.0 H5'' B:DC112 3.6 38.3 1.0 O2A A:XG4907 3.7 29.2 1.0 H5'A A:XG4907 3.8 36.6 1.0 O5' A:XG4907 4.0 28.9 1.0 O A:HOH1155 4.1 43.4 1.0 HB3 A:GLU786 4.1 41.8 1.0 H5' A:XG4907 4.1 36.6 1.0 H A:ASP785 4.1 31.6 1.0 H4' B:DC112 4.2 40.4 1.0 C4' B:DC112 4.2 33.6 1.0 C5' A:XG4907 4.2 30.4 1.0 CB A:GLU786 4.2 34.8 1.0 OE1 A:GLU786 4.3 35.9 1.0 C5' B:DC112 4.3 31.9 1.0 O A:VAL783 4.4 30.6 1.0 CB A:ASP610 4.4 29.7 1.0 CB A:ASP785 4.5 27.4 1.0 HB2 A:ASP610 4.5 35.7 1.0 C A:ASP785 4.6 29.6 1.0 C2' B:DC112 4.6 34.6 1.0 O A:ASP785 4.7 29.2 1.0 H2'' B:DC112 4.7 41.5 1.0 N3A A:XG4907 4.7 32.5 1.0 N A:GLU786 4.8 32.4 1.0 O3G A:XG4907 4.8 29.4 1.0 O5' B:DC112 4.8 31.0 1.0 HB3 A:ASP785 4.8 32.9 1.0 N A:ASP785 4.8 26.3 1.0 CA A:ASP785 4.9 27.4 1.0 H2' B:DC112 4.9 41.5 1.0 HA A:ASP610 4.9 33.7 1.0

H.M.Kropp, S.L.Durr, C.Peter, K.Diederichs, A.Marx. Snapshots of A Modified Nucleotide Moving Through the Confines of A Dna Polymerase. Proc. Natl. Acad. Sci. V. 115 9992 2018U.S.A..
ISSN: ESSN 1091-6490
PubMed: 30224478
DOI: 10.1073/PNAS.1811518115