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Atomistry » Manganese » PDB 6dkt-6e4c » 6dqc | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Manganese » PDB 6dkt-6e4c » 6dqc » |
Manganese in PDB 6dqc: Linked KDM5A Jmj Domain Bound to the Inhibitor N50 I.E. 2-(4-((2- (Dimethylamino)Ethyl)(Ethyl)Carbamoyl)-5-(4-Methoxyphenyl)-1H- Pyrazol-1-Yl)Isonicotinic AcidProtein crystallography data
The structure of Linked KDM5A Jmj Domain Bound to the Inhibitor N50 I.E. 2-(4-((2- (Dimethylamino)Ethyl)(Ethyl)Carbamoyl)-5-(4-Methoxyphenyl)-1H- Pyrazol-1-Yl)Isonicotinic Acid, PDB code: 6dqc
was solved by
J.R.Horton,
X.Cheng,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Manganese Binding Sites:
The binding sites of Manganese atom in the Linked KDM5A Jmj Domain Bound to the Inhibitor N50 I.E. 2-(4-((2- (Dimethylamino)Ethyl)(Ethyl)Carbamoyl)-5-(4-Methoxyphenyl)-1H- Pyrazol-1-Yl)Isonicotinic Acid
(pdb code 6dqc). This binding sites where shown within
5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Linked KDM5A Jmj Domain Bound to the Inhibitor N50 I.E. 2-(4-((2- (Dimethylamino)Ethyl)(Ethyl)Carbamoyl)-5-(4-Methoxyphenyl)-1H- Pyrazol-1-Yl)Isonicotinic Acid, PDB code: 6dqc: Manganese binding site 1 out of 1 in 6dqcGo back to Manganese Binding Sites List in 6dqc
Manganese binding site 1 out
of 1 in the Linked KDM5A Jmj Domain Bound to the Inhibitor N50 I.E. 2-(4-((2- (Dimethylamino)Ethyl)(Ethyl)Carbamoyl)-5-(4-Methoxyphenyl)-1H- Pyrazol-1-Yl)Isonicotinic Acid
Mono view Stereo pair view
Reference:
J.R.Horton,
X.Liu,
C.B.Woodcock,
J.Shanks,
X.Zhang,
G.Rai,
B.Mott,
D.J.Jansen,
S.Kales,
M.J.Henderson,
K.Pohida,
Y.Fang,
X.Hu,
A.Jadhav,
D.Maloney,
M.D.Hall,
A.Simeonov,
H.Fu,
P.M.Vertino,
X.Cheng.
To Be Determined To Be Published.
Page generated: Tue Dec 15 04:52:01 2020
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