Manganese in PDB 5y6n: Zika Virus Helicase in Complex with Adp

The structure of Zika Virus Helicase in Complex with Adp, PDB code: 5y6n was solved by X.Y.Yang, C.Chen, H.L.Tian, H.Chi, Z.Y.Mu, T.Q.Zhang, K.L.Yang, Q.Zhao, X.H.Liu, Z.F.Wang, X.Y.Ji, H.T.Yang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.34 / 1.57
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	63.275, 52.934, 64.483, 90.00, 104.93, 90.00
R / Rfree (%)	18.2 / 20.2

The binding sites of Manganese atom in the Zika Virus Helicase in Complex with Adp (pdb code 5y6n). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Zika Virus Helicase in Complex with Adp, PDB code: 5y6n:

Manganese binding site 1 out of 1 in the Zika Virus Helicase in Complex with Adp


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Zika Virus Helicase in Complex with Adp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn701 b:17.3 occ:1.00 OE2 A:GLU286 2.2 17.3 1.0 O3B A:ADP702 2.2 17.3 1.0 OG1 A:THR201 2.2 17.5 1.0 O A:HOH846 2.2 19.0 1.0 O A:HOH849 2.3 18.4 1.0 O A:HOH854 2.3 23.4 1.0 CD A:GLU286 3.1 19.2 1.0 CB A:THR201 3.3 15.8 1.0 PB A:ADP702 3.3 16.8 1.0 OE1 A:GLU286 3.4 22.1 1.0 O2B A:ADP702 3.6 16.3 1.0 O A:HOH837 4.0 25.3 1.0 OD1 A:ASP285 4.0 16.9 1.0 N A:THR201 4.0 17.8 1.0 O2A A:ADP702 4.0 18.0 1.0 OD2 A:ASP285 4.1 16.7 1.0 CA A:THR201 4.2 17.2 1.0 O A:HOH910 4.3 23.6 1.0 CG2 A:THR201 4.3 21.0 1.0 O3A A:ADP702 4.4 16.0 1.0 CG A:ASP285 4.4 16.4 1.0 O1B A:ADP702 4.4 17.9 1.0 O A:HOH1009 4.5 26.0 1.0 CG A:GLU286 4.5 16.6 1.0 PA A:ADP702 4.6 19.2 1.0 O A:HOH994 4.8 20.9 1.0 CB A:LYS200 4.8 14.7 1.0 O A:HOH1070 4.8 10.9 1.0 CE A:LYS200 4.9 15.7 1.0 CA A:GLY415 5.0 18.5 1.0

X.Yang, C.Chen, H.Tian, H.Chi, Z.Mu, T.Zhang, K.Yang, Q.Zhao, X.Liu, Z.Wang, X.Ji, H.Yang. Mechanism of Atp Hydrolysis By the Zika Virus Helicase. Faseb J. V. 32 5250 2018.
ISSN: ESSN 1530-6860
PubMed: 29913559
DOI: 10.1096/FJ.201701140R