Manganese in PDB 5y4z: Crystal Structure of the Zika Virus NS3 Helicase Complex with Amppnp

All present enzymatic activity of Crystal Structure of the Zika Virus NS3 Helicase Complex with Amppnp:
3.4.21.91; 3.6.1.15; 3.6.4.13;

The structure of Crystal Structure of the Zika Virus NS3 Helicase Complex with Amppnp, PDB code: 5y4z was solved by L.Li, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.94 / 1.30
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	53.754, 68.779, 56.971, 90.00, 92.50, 90.00
R / Rfree (%)	19.2 / 21.6

The binding sites of Manganese atom in the Crystal Structure of the Zika Virus NS3 Helicase Complex with Amppnp (pdb code 5y4z). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Crystal Structure of the Zika Virus NS3 Helicase Complex with Amppnp, PDB code: 5y4z:

Manganese binding site 1 out of 1 in the Crystal Structure of the Zika Virus NS3 Helicase Complex with Amppnp


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Crystal Structure of the Zika Virus NS3 Helicase Complex with Amppnp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn702 b:24.3 occ:1.00 O A:HOH830 2.2 29.3 1.0 O3G A:ANP701 2.3 24.6 1.0 O A:HOH863 2.3 23.1 1.0 O2B A:ANP701 2.3 24.4 1.0 OE2 A:GLU286 2.4 27.1 1.0 OG1 A:THR201 2.4 27.2 1.0 CD A:GLU286 3.2 26.0 1.0 PG A:ANP701 3.3 25.1 1.0 PB A:ANP701 3.4 24.6 1.0 OE1 A:GLU286 3.4 23.9 1.0 N3B A:ANP701 3.5 25.3 1.0 CB A:THR201 3.5 27.2 1.0 O A:HOH842 3.7 27.8 1.0 O2A A:ANP701 3.9 28.2 1.0 OD1 A:ASP285 4.0 24.7 1.0 OD2 A:ASP285 4.1 26.0 1.0 O A:HOH1112 4.2 29.1 1.0 N A:THR201 4.2 27.1 1.0 O2G A:ANP701 4.2 22.6 1.0 CA A:THR201 4.4 26.9 1.0 O3A A:ANP701 4.4 25.9 1.0 O A:HOH1002 4.5 30.4 1.0 O1B A:ANP701 4.5 24.5 1.0 CG A:ASP285 4.5 24.2 1.0 O1G A:ANP701 4.5 25.7 1.0 O A:HOH1039 4.5 18.4 1.0 CG A:GLU286 4.6 20.9 1.0 CG2 A:THR201 4.6 29.6 1.0 O A:HOH987 4.6 23.3 1.0 PA A:ANP701 4.6 28.9 1.0 O A:HOH803 4.9 50.9 1.0 CE A:LYS200 4.9 23.2 1.0 CB A:LYS200 4.9 25.5 1.0 CA A:GLY415 5.0 24.8 1.0

L.Li, J.Wang, Z.Jia, N.Shaw. Structural View of the Helicase Reveals That Zika Virus Uses A Conserved Mechanism For Unwinding Rna Acta Crystallogr.,Sect.F V. 74 205 2018.
ISSN: ESSN 2053-230X
DOI: 10.1107/S2053230X18003813