Manganese in PDB 5n8x: Trigonal Structure of Mutant V173I of 3D Polymerase From Foot-and- Mouth Disease Virus

The structure of Trigonal Structure of Mutant V173I of 3D Polymerase From Foot-and- Mouth Disease Virus, PDB code: 5n8x was solved by C.Ferrer-Orta, N.Verdaguer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.75 / 2.40
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	93.506, 93.506, 99.626, 90.00, 90.00, 120.00
R / Rfree (%)	25.2 / 28.1

The binding sites of Manganese atom in the Trigonal Structure of Mutant V173I of 3D Polymerase From Foot-and- Mouth Disease Virus (pdb code 5n8x). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Trigonal Structure of Mutant V173I of 3D Polymerase From Foot-and- Mouth Disease Virus, PDB code: 5n8x:

Manganese binding site 1 out of 1 in the Trigonal Structure of Mutant V173I of 3D Polymerase From Foot-and- Mouth Disease Virus


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Trigonal Structure of Mutant V173I of 3D Polymerase From Foot-and- Mouth Disease Virus within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn501 b:0.5 occ:1.00 OD1 A:ASP238 2.5 59.0 1.0 OD1 A:ASP240 3.1 59.3 1.0 OD1 A:ASP339 3.2 49.5 1.0 O A:THR384 3.3 54.2 1.0 CG A:ASP238 3.5 60.5 1.0 OD2 A:ASP238 3.8 60.8 1.0 C A:THR384 4.3 54.1 1.0 CG A:ASP339 4.3 48.5 1.0 CG A:ASP240 4.3 61.5 1.0 O A:VAL239 4.4 56.9 1.0 O A:ILE340 4.7 52.0 1.0 CB A:THR384 4.7 57.2 1.0 OD2 A:ASP339 4.8 48.5 1.0 OD2 A:ASP240 4.9 63.5 1.0 CB A:ASP238 4.9 62.6 1.0 C A:VAL239 4.9 59.1 1.0 CG2 A:THR384 4.9 55.5 1.0 CB A:ALA367 5.0 69.9 1.0

I.De La Higuera, C.Ferrer-Orta, A.I.De Avila, C.Perales, M.Sierra, K.Singh, S.G.Sarafianos, Y.Dehouck, U.Bastolla, N.Verdaguer, E.Domingo. Molecular and Functional Bases of Selection Against A Mutation Bias in An Rna Virus. Genome Biol Evol V. 9 1212 2017.
ISSN: ISSN 1759-6653
PubMed: 28460010
DOI: 10.1093/GBE/EVX075