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Manganese in PDB 5juc: Crystal Structure of Glucosyl-3-Phosphoglycerate Synthase From Mycobacterium Tuberculosis in Complex with MN2+, Uridine-Diphosphate (Udp) and Glucosyl-3-Phosphoglycerate (Gpg) - Gpgs*Gpg*Udp*MN2+_2

Enzymatic activity of Crystal Structure of Glucosyl-3-Phosphoglycerate Synthase From Mycobacterium Tuberculosis in Complex with MN2+, Uridine-Diphosphate (Udp) and Glucosyl-3-Phosphoglycerate (Gpg) - Gpgs*Gpg*Udp*MN2+_2

All present enzymatic activity of Crystal Structure of Glucosyl-3-Phosphoglycerate Synthase From Mycobacterium Tuberculosis in Complex with MN2+, Uridine-Diphosphate (Udp) and Glucosyl-3-Phosphoglycerate (Gpg) - Gpgs*Gpg*Udp*MN2+_2:
2.4.1.266;

Protein crystallography data

The structure of Crystal Structure of Glucosyl-3-Phosphoglycerate Synthase From Mycobacterium Tuberculosis in Complex with MN2+, Uridine-Diphosphate (Udp) and Glucosyl-3-Phosphoglycerate (Gpg) - Gpgs*Gpg*Udp*MN2+_2, PDB code: 5juc was solved by D.Albesa-Jove, E.Sancho-Vaello, A.Rodrigo-Unzueta, N.Comino, A.Carreras-Gonzalez, P.Arrasate, S.Urresti, M.E.Guerin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 70.31 / 2.80
Space group I 41
Cell size a, b, c (Å), α, β, γ (°) 99.434, 99.434, 126.785, 90.00, 90.00, 90.00
R / Rfree (%) 19.1 / 21.8

Manganese Binding Sites:

The binding sites of Manganese atom in the Crystal Structure of Glucosyl-3-Phosphoglycerate Synthase From Mycobacterium Tuberculosis in Complex with MN2+, Uridine-Diphosphate (Udp) and Glucosyl-3-Phosphoglycerate (Gpg) - Gpgs*Gpg*Udp*MN2+_2 (pdb code 5juc). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Crystal Structure of Glucosyl-3-Phosphoglycerate Synthase From Mycobacterium Tuberculosis in Complex with MN2+, Uridine-Diphosphate (Udp) and Glucosyl-3-Phosphoglycerate (Gpg) - Gpgs*Gpg*Udp*MN2+_2, PDB code: 5juc:

Manganese binding site 1 out of 1 in 5juc

Go back to Manganese Binding Sites List in 5juc
Manganese binding site 1 out of 1 in the Crystal Structure of Glucosyl-3-Phosphoglycerate Synthase From Mycobacterium Tuberculosis in Complex with MN2+, Uridine-Diphosphate (Udp) and Glucosyl-3-Phosphoglycerate (Gpg) - Gpgs*Gpg*Udp*MN2+_2


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Crystal Structure of Glucosyl-3-Phosphoglycerate Synthase From Mycobacterium Tuberculosis in Complex with MN2+, Uridine-Diphosphate (Udp) and Glucosyl-3-Phosphoglycerate (Gpg) - Gpgs*Gpg*Udp*MN2+_2 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mn404

b:85.8
occ:0.35
 OD1 A:ASP136 2.1 82.6 1.0
ND1 A:HIS258 2.3 0.6 1.0
O A:HOH515 2.4 94.5 1.0
CG A:ASP136 3.0 73.8 1.0
OD2 A:ASP136 3.1 66.0 1.0
CE1 A:HIS258 3.2 0.1 1.0
CG A:HIS258 3.3 1.0 1.0
CB A:HIS258 3.7 99.5 1.0
O A:HOH518 3.7 86.4 1.0
O3A A:UDP401 3.8 1.0 1.0
O1A A:UDP401 3.8 89.9 1.0
C6 A:XDX405 4.2 0.7 0.7
C5' A:UDP401 4.2 71.9 1.0
O A:HOH522 4.3 0.9 1.0
PA A:UDP401 4.3 0.5 1.0
NE2 A:HIS258 4.3 1.0 1.0
CB A:ASP136 4.4 65.9 1.0
CD2 A:HIS258 4.4 0.2 1.0
OD2 A:ASP134 4.5 68.8 1.0
C5 A:XDX405 4.5 0.7 0.7
O A:HOH511 4.7 68.9 1.0
O5' A:UDP401 4.7 74.4 1.0
O A:ARG259 4.8 0.4 1.0
NH2 A:ARG256 4.8 0.5 1.0
PB A:UDP401 4.9 0.1 1.0

Reference:

D.Albesa-Jove, J.Romero-Garcia, E.Sancho-Vaello, F.X.Contreras, A.Rodrigo-Unzueta, N.Comino, A.Carreras-Gonzalez, P.Arrasate, S.Urresti, X.Biarnes, A.Planas, M.E.Guerin. Structural Snapshots and Loop Dynamics Along the Catalytic Cycle of Glycosyltransferase Gpgs. Structure V. 25 1034 2017.
ISSN: ISSN 1878-4186
PubMed: 28625787
DOI: 10.1016/J.STR.2017.05.009
Page generated: Tue Dec 15 04:42:34 2020

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