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Atomistry » Manganese » PDB 5hzz-5jpf » 5jhu | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Manganese » PDB 5hzz-5jpf » 5jhu » |
Manganese in PDB 5jhu: Potent, Reversible METAP2 Inhibitors Via FbddEnzymatic activity of Potent, Reversible METAP2 Inhibitors Via Fbdd
All present enzymatic activity of Potent, Reversible METAP2 Inhibitors Via Fbdd:
3.4.11.18; Protein crystallography data
The structure of Potent, Reversible METAP2 Inhibitors Via Fbdd, PDB code: 5jhu
was solved by
D.R.Dougan,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Manganese Binding Sites:
The binding sites of Manganese atom in the Potent, Reversible METAP2 Inhibitors Via Fbdd
(pdb code 5jhu). This binding sites where shown within
5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Potent, Reversible METAP2 Inhibitors Via Fbdd, PDB code: 5jhu: Jump to Manganese binding site number: 1; 2; Manganese binding site 1 out of 2 in 5jhuGo back to Manganese Binding Sites List in 5jhu
Manganese binding site 1 out
of 2 in the Potent, Reversible METAP2 Inhibitors Via Fbdd
Mono view Stereo pair view
Manganese binding site 2 out of 2 in 5jhuGo back to Manganese Binding Sites List in 5jhu
Manganese binding site 2 out
of 2 in the Potent, Reversible METAP2 Inhibitors Via Fbdd
Mono view Stereo pair view
Reference:
Z.Cheruvallath,
M.Tang,
C.Mcbride,
M.Komandla,
J.Miura,
T.Ton-Nu,
P.Erikson,
J.Feng,
P.Farrell,
J.D.Lawson,
D.Vanderpool,
Y.Wu,
D.R.Dougan,
A.Plonowski,
C.Holub,
C.Larson.
Discovery of Potent, Reversible METAP2 Inhibitors Via Fragment Based Drug Discovery and Structure Based Drug Design-Part 1. Bioorg.Med.Chem.Lett. V. 26 2774 2016.
Page generated: Tue Dec 15 04:42:19 2020
ISSN: ESSN 1464-3405 PubMed: 27155900 DOI: 10.1016/J.BMCL.2016.04.073 |
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