Manganese in PDB 5j1n: Lassa Virus L Protein Cap-Snatching Endonuclease. Bound to One Manganese Ion

All present enzymatic activity of Lassa Virus L Protein Cap-Snatching Endonuclease. Bound to One Manganese Ion:
2.7.7.48;

The structure of Lassa Virus L Protein Cap-Snatching Endonuclease. Bound to One Manganese Ion, PDB code: 5j1n was solved by J.Reguera, S.Cusack, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.45 / 1.09
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	51.500, 51.500, 143.000, 90.00, 90.00, 90.00
R / Rfree (%)	16.1 / 17.9

The binding sites of Manganese atom in the Lassa Virus L Protein Cap-Snatching Endonuclease. Bound to One Manganese Ion (pdb code 5j1n). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Lassa Virus L Protein Cap-Snatching Endonuclease. Bound to One Manganese Ion, PDB code: 5j1n:

Manganese binding site 1 out of 1 in the Lassa Virus L Protein Cap-Snatching Endonuclease. Bound to One Manganese Ion


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Lassa Virus L Protein Cap-Snatching Endonuclease. Bound to One Manganese Ion within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn1001 b:6.9 occ:0.70 OE1 A:GLU102 2.1 10.3 1.0 O A:HOH1255 2.2 12.1 1.0 O A:HOH1119 2.2 9.8 1.0 OD2 A:ASP89 2.2 9.4 1.0 O A:HOH1178 2.2 10.2 1.0 CD A:GLU102 3.0 9.8 1.0 CG A:ASP89 3.1 8.3 1.0 OE2 A:GLU102 3.4 11.4 1.0 OD1 A:ASP89 3.4 12.2 1.0 NZ A:LYS122 4.0 13.2 1.0 O A:CYS103 4.1 5.7 0.3 O A:CYS103 4.1 9.1 0.3 O A:CYS103 4.2 12.2 0.3 OD2 A:ASP119 4.2 10.8 1.0 CG A:GLU102 4.3 9.7 1.0 N A:CYS103 4.4 6.4 0.3 CB A:GLU102 4.4 9.2 1.0 O A:HOH1256 4.4 14.2 1.0 CB A:ASP89 4.5 8.1 1.0 N A:CYS103 4.5 9.0 0.3 CA A:GLU102 4.5 8.5 1.0 OD1 A:ASP119 4.6 12.0 1.0 N A:CYS103 4.6 10.8 0.3 O A:HOH1280 4.6 13.5 1.0 CG A:ASP119 4.7 10.1 1.0 N A:ASP89 4.7 7.2 1.0 NZ A:LYS115 4.8 17.3 1.0

J.Reguera, P.Gerlach, M.Rosenthal, S.Gaudon, F.Coscia, S.Gunther, S.Cusack. Comparative Structural and Functional Analysis of Bunyavirus and Arenavirus Cap-Snatching Endonucleases. Plos Pathog. V. 12 05636 2016.
ISSN: ESSN 1553-7374
PubMed: 27304209
DOI: 10.1371/JOURNAL.PPAT.1005636