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Atomistry » Manganese » PDB 5hzz-5jpf » 5iwm | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Manganese » PDB 5hzz-5jpf » 5iwm » |
Manganese in PDB 5iwm: 2.5A Structure of GSK945237 with S.Aureus Dna Gyrase and Dna.Enzymatic activity of 2.5A Structure of GSK945237 with S.Aureus Dna Gyrase and Dna.
All present enzymatic activity of 2.5A Structure of GSK945237 with S.Aureus Dna Gyrase and Dna.:
5.99.1.3; Protein crystallography data
The structure of 2.5A Structure of GSK945237 with S.Aureus Dna Gyrase and Dna., PDB code: 5iwm
was solved by
B.D.Bax,
T.J.Miles,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5iwm:
The structure of 2.5A Structure of GSK945237 with S.Aureus Dna Gyrase and Dna. also contains other interesting chemical elements:
Manganese Binding Sites:
The binding sites of Manganese atom in the 2.5A Structure of GSK945237 with S.Aureus Dna Gyrase and Dna.
(pdb code 5iwm). This binding sites where shown within
5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the 2.5A Structure of GSK945237 with S.Aureus Dna Gyrase and Dna., PDB code: 5iwm: Jump to Manganese binding site number: 1; 2; Manganese binding site 1 out of 2 in 5iwmGo back to Manganese Binding Sites List in 5iwm
Manganese binding site 1 out
of 2 in the 2.5A Structure of GSK945237 with S.Aureus Dna Gyrase and Dna.
Mono view Stereo pair view
Manganese binding site 2 out of 2 in 5iwmGo back to Manganese Binding Sites List in 5iwm
Manganese binding site 2 out
of 2 in the 2.5A Structure of GSK945237 with S.Aureus Dna Gyrase and Dna.
Mono view Stereo pair view
Reference:
T.J.Miles,
A.J.Hennessy,
B.Bax,
G.Brooks,
B.S.Brown,
P.Brown,
N.Cailleau,
D.Chen,
S.Dabbs,
D.T.Davies,
J.M.Esken,
I.Giordano,
J.L.Hoover,
G.E.Jones,
S.K.Kusalakumari Sukmar,
R.E.Markwell,
E.A.Minthorn,
S.Rittenhouse,
M.N.Gwynn,
N.D.Pearson.
Novel Tricyclics (E.G., GSK945237) As Potent Inhibitors of Bacterial Type Iia Topoisomerases. Bioorg.Med.Chem.Lett. V. 26 2464 2016.
Page generated: Tue Dec 15 04:42:07 2020
ISSN: ESSN 1464-3405 PubMed: 27055939 DOI: 10.1016/J.BMCL.2016.03.106 |
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