|
Atomistry » Manganese » PDB 5hzz-5jpf » 5iwf | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Manganese » PDB 5hzz-5jpf » 5iwf » |
Manganese in PDB 5iwf: Linked KDM5A Jmj Domain Bound to the Inhibitor 2-(((2-((2- (Dimethylamino)Ethyl)(Ethyl)Amino)-2-Oxoethyl)Amino)Methyl) IsonicotinamidProtein crystallography data
The structure of Linked KDM5A Jmj Domain Bound to the Inhibitor 2-(((2-((2- (Dimethylamino)Ethyl)(Ethyl)Amino)-2-Oxoethyl)Amino)Methyl) Isonicotinamid, PDB code: 5iwf
was solved by
J.R.Horton,
X.Cheng,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Manganese Binding Sites:
The binding sites of Manganese atom in the Linked KDM5A Jmj Domain Bound to the Inhibitor 2-(((2-((2- (Dimethylamino)Ethyl)(Ethyl)Amino)-2-Oxoethyl)Amino)Methyl) Isonicotinamid
(pdb code 5iwf). This binding sites where shown within
5.0 Angstroms radius around Manganese atom.
In total only one binding site of Manganese was determined in the Linked KDM5A Jmj Domain Bound to the Inhibitor 2-(((2-((2- (Dimethylamino)Ethyl)(Ethyl)Amino)-2-Oxoethyl)Amino)Methyl) Isonicotinamid, PDB code: 5iwf: Manganese binding site 1 out of 1 in 5iwfGo back to Manganese Binding Sites List in 5iwf
Manganese binding site 1 out
of 1 in the Linked KDM5A Jmj Domain Bound to the Inhibitor 2-(((2-((2- (Dimethylamino)Ethyl)(Ethyl)Amino)-2-Oxoethyl)Amino)Methyl) Isonicotinamid
Mono view Stereo pair view
Reference:
J.R.Horton,
X.Liu,
M.Gale,
L.Wu,
J.R.Shanks,
X.Zhang,
P.J.Webber,
J.S.Bell,
S.C.Kales,
B.T.Mott,
G.Rai,
D.J.Jansen,
M.J.Henderson,
D.J.Urban,
M.D.Hall,
A.Simeonov,
D.J.Maloney,
M.A.Johns,
H.Fu,
A.Jadhav,
P.M.Vertino,
Q.Yan,
X.Cheng.
Structural Basis For KDM5A Histone Lysine Demethylase Inhibition By Diverse Compounds. Cell Chem Biol V. 23 769 2016.
Page generated: Sun Oct 6 01:28:20 2024
ISSN: ESSN 2451-9456 PubMed: 27427228 DOI: 10.1016/J.CHEMBIOL.2016.06.006 |
Last articlesZn in 9JYWZn in 9IR4 Zn in 9IR3 Zn in 9GMX Zn in 9GMW Zn in 9JEJ Zn in 9ERF Zn in 9ERE Zn in 9EGV Zn in 9EGW |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |