Manganese in PDB 5fzo: Crystal Structure of the Catalytic Domain of Human JMJD1C

The structure of Crystal Structure of the Catalytic Domain of Human JMJD1C, PDB code: 5fzo was solved by R.Nowak, R.Talon, T.Krojer, S.Goubin, M.Mcdonough, M.Fairhead, U.Oppermann, C.Johansson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	55.460 / 1.84
Space group	P 2 21 21
Cell size a, b, c (Å), α, β, γ (°)	45.320, 110.920, 165.310, 90.00, 90.00, 90.00
R / Rfree (%)	19.25 / 23.14

The structure of Crystal Structure of the Catalytic Domain of Human JMJD1C also contains other interesting chemical elements:

Chlorine

(Cl)

2 atoms

The binding sites of Manganese atom in the Crystal Structure of the Catalytic Domain of Human JMJD1C (pdb code 5fzo). This binding sites where shown within 5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Crystal Structure of the Catalytic Domain of Human JMJD1C, PDB code: 5fzo:
Jump to Manganese binding site number: 1; 2;

Manganese binding site 1 out of 2 in the Crystal Structure of the Catalytic Domain of Human JMJD1C


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 1 of Crystal Structure of the Catalytic Domain of Human JMJD1C within 5.0Å range: probe atom residue distance (Å) B Occ A:Mn3499 b:21.9 occ:0.62 O A:HOH3198 2.1 26.9 1.0 OE2 A:GLU2338 2.1 29.0 1.0 O A:HOH3202 2.2 30.8 1.0 NE2 A:HIS2336 2.2 22.6 1.0 NE2 A:HIS2466 2.2 29.7 1.0 O A:HOH3197 2.3 34.2 1.0 CE1 A:HIS2336 2.9 21.5 1.0 CD A:GLU2338 3.0 29.9 1.0 CD2 A:HIS2466 3.1 22.8 1.0 CE1 A:HIS2466 3.2 20.4 1.0 OE1 A:GLU2338 3.3 30.7 1.0 CD2 A:HIS2336 3.4 28.8 1.0 ND1 A:HIS2336 4.1 24.5 1.0 O A:HOH3290 4.2 45.9 1.0 O A:HOH3193 4.3 43.0 1.0 CG A:HIS2466 4.3 19.3 1.0 ND1 A:HIS2466 4.3 21.1 1.0 ND2 A:ASN2344 4.4 27.2 1.0 CG A:GLU2338 4.4 28.8 1.0 CG A:HIS2336 4.4 25.1 1.0 O A:HOH3199 4.5 44.8 1.0

Manganese binding site 2 out of 2 in the Crystal Structure of the Catalytic Domain of Human JMJD1C


Mono view


Stereo pair view

A full contact list of Manganese with other atoms in the Mn binding site number 2 of Crystal Structure of the Catalytic Domain of Human JMJD1C within 5.0Å range: probe atom residue distance (Å) B Occ B:Mn3499 b:66.7 occ:1.00 OE2 B:GLU2338 2.1 54.7 1.0 NE2 B:HIS2466 2.2 29.4 1.0 O B:HOH3140 2.5 42.9 1.0 NE2 B:HIS2336 2.6 35.5 1.0 O B:HOH3143 2.7 39.7 1.0 CE1 B:HIS2336 3.0 33.4 1.0 CE1 B:HIS2466 3.0 35.0 1.0 CD B:GLU2338 3.1 51.5 1.0 CD2 B:HIS2466 3.3 25.1 1.0 OE1 B:GLU2338 3.5 45.6 1.0 CD2 B:HIS2336 3.9 42.3 1.0 ND1 B:HIS2466 4.2 31.9 1.0 O2 B:EDO3503 4.2 40.7 1.0 ND1 B:HIS2336 4.3 34.2 1.0 O B:HOH3125 4.3 56.1 1.0 CG B:HIS2466 4.4 28.9 1.0 CG B:GLU2338 4.4 41.8 1.0 OD1 B:ASN2344 4.6 28.6 0.4 CG B:HIS2336 4.7 35.7 1.0 CG2 B:THR2333 5.0 28.1 1.0

R.Nowak, S.Goubin, M.Mcdonough, M.Fairhead, U.Oppermann, C.Johansson. Crystal Structure of the Catalytic Domain of Human JMJD1C To Be Published.