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Atomistry » Manganese » PDB 5a58-5b49 » 5a7s » |
Manganese in PDB 5a7s: Crystal Structure of Human JMJD2A in Complex with Compound 44Enzymatic activity of Crystal Structure of Human JMJD2A in Complex with Compound 44
All present enzymatic activity of Crystal Structure of Human JMJD2A in Complex with Compound 44:
1.14.11.27; Protein crystallography data
The structure of Crystal Structure of Human JMJD2A in Complex with Compound 44, PDB code: 5a7s
was solved by
R.Nowak,
S.Velupillai,
T.Krojer,
C.Gileadi,
C.Johansson,
M.Korczynska,
D.D.Le,
N.Younger,
E.Gregori-Puigjane,
A.Tumber,
E.Iwasa,
S.B.Pollock,
I.Ortiz Torres,
J.Kopec,
C.Tallant,
S.Froese,
F.Von Delft,
C.H.Arrowsmith,
C.Bountra,
A.Edwards,
B.K.Shoichet,
D.G.Fujimori,
U.Oppermann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 5a7s:
The structure of Crystal Structure of Human JMJD2A in Complex with Compound 44 also contains other interesting chemical elements:
Manganese Binding Sites:
The binding sites of Manganese atom in the Crystal Structure of Human JMJD2A in Complex with Compound 44
(pdb code 5a7s). This binding sites where shown within
5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Crystal Structure of Human JMJD2A in Complex with Compound 44, PDB code: 5a7s: Jump to Manganese binding site number: 1; 2; Manganese binding site 1 out of 2 in 5a7sGo back to Manganese Binding Sites List in 5a7s
Manganese binding site 1 out
of 2 in the Crystal Structure of Human JMJD2A in Complex with Compound 44
Mono view Stereo pair view
Manganese binding site 2 out of 2 in 5a7sGo back to Manganese Binding Sites List in 5a7s
Manganese binding site 2 out
of 2 in the Crystal Structure of Human JMJD2A in Complex with Compound 44
Mono view Stereo pair view
Reference:
M.Korczynska,
D.D.Le,
N.Younger,
E.Gregori-Puigjane,
A.Tumber,
T.Krojer,
S.Velupillai,
C.Gileadi,
R.P.Nowak,
E.Iwasa,
S.B.Pollock,
I.Ortiz Torres,
U.Oppermann,
B.K.Shoichet,
D.G.Fujimori.
Docking and Linking of Fragments to Discover Jumonji Histone Demethylase Inhibitors. J.Med.Chem. V. 59 1580 2016.
Page generated: Tue Dec 15 04:35:19 2020
ISSN: ISSN 0022-2623 PubMed: 26699912 DOI: 10.1021/ACS.JMEDCHEM.5B01527 |
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