Manganese »
PDB 4z8b-5a56 »
4zvz »
Manganese in PDB 4zvz: Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid
Enzymatic activity of Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid
All present enzymatic activity of Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid:
3.1.3.16;
3.1.3.16;
Protein crystallography data
The structure of Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid, PDB code: 4zvz
was solved by
D.Chattopadhyay,
M.R.Swingle,
E.A.Salter,
A.Wierzbicki,
R.E.Honkanen,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 91.03 / 2.00 |
| Space group | P 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 40.858, 80.520, 91.165, 88.15, 87.33, 86.71 |
| R / Rfree (%) | 20.4 / 23.5 |
Other elements in 4zvz:
The structure of Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid also contains other interesting chemical elements:
| Sodium | (Na) | 1 atom |
Manganese Binding Sites:
The binding sites of Manganese atom in the Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid
(pdb code 4zvz). This binding sites where shown within
5.0 Angstroms radius around Manganese atom.
In total 8 binding sites of Manganese where determined in the Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid, PDB code: 4zvz:
Jump to Manganese binding site number: 1; 2; 3; 4; 5; 6; 7; 8;
In total 8 binding sites of Manganese where determined in the Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid, PDB code: 4zvz:
Jump to Manganese binding site number: 1; 2; 3; 4; 5; 6; 7; 8;
Manganese binding site 1 out of 8 in 4zvz
Go back to
Manganese Binding Sites List in 4zvz
Manganese binding site 1 out
of 8 in the Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 1 of Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid within 5.0Å range:
|
Manganese binding site 2 out of 8 in 4zvz
Go back to
Manganese Binding Sites List in 4zvz
Manganese binding site 2 out
of 8 in the Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 2 of Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid within 5.0Å range:
|
Manganese binding site 3 out of 8 in 4zvz
Go back to
Manganese Binding Sites List in 4zvz
Manganese binding site 3 out
of 8 in the Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 3 of Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid within 5.0Å range:
|
Manganese binding site 4 out of 8 in 4zvz
Go back to
Manganese Binding Sites List in 4zvz
Manganese binding site 4 out
of 8 in the Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 4 of Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid within 5.0Å range:
|
Manganese binding site 5 out of 8 in 4zvz
Go back to
Manganese Binding Sites List in 4zvz
Manganese binding site 5 out
of 8 in the Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 5 of Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid within 5.0Å range:
|
Manganese binding site 6 out of 8 in 4zvz
Go back to
Manganese Binding Sites List in 4zvz
Manganese binding site 6 out
of 8 in the Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 6 of Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid within 5.0Å range:
|
Manganese binding site 7 out of 8 in 4zvz
Go back to
Manganese Binding Sites List in 4zvz
Manganese binding site 7 out
of 8 in the Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 7 of Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid within 5.0Å range:
|
Manganese binding site 8 out of 8 in 4zvz
Go back to
Manganese Binding Sites List in 4zvz
Manganese binding site 8 out
of 8 in the Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 8 of Co-Crystal Structures of PP5 in Complex with 5-Methyl-7- Oxabicyclo[2.2.1]Heptane-2,3-Dicarboxylic Acid within 5.0Å range:
|
Reference:
D.Chattopadhyay,
M.R.Swingle,
E.A.Salter,
E.Wood,
B.D'arcy,
C.Zivanov,
K.Abney,
A.Musiyenko,
S.F.Rusin,
A.Kettenbach,
L.Yet,
C.E.Schroeder,
J.E.Golden,
W.H.Dunham,
A.C.Gingras,
S.Banerjee,
D.Forbes,
A.Wierzbicki,
R.E.Honkanen.
Crystal Structures and Mutagenesis of Ppp-Family Ser/Thr Protein Phosphatases Elucidate the Selectivity of Cantharidin and Novel Norcantharidin-Based Inhibitors of PP5C. Biochem. Pharmacol. V. 109 14 2016.
ISSN: ISSN 1873-2968
PubMed: 27002182
DOI: 10.1016/J.BCP.2016.03.011
Page generated: Sat Oct 5 23:15:41 2024
ISSN: ISSN 1873-2968
PubMed: 27002182
DOI: 10.1016/J.BCP.2016.03.011
Last articles
Zn in 9JPJZn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
