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Manganese in PDB 4z6f: Structure of Human Dna Polymerase Beta 279NA Mutant Complexed with G in the Template Base Paired with Incoming Non-Hydrolyzable Ttp and Manganese
Enzymatic activity of Structure of Human Dna Polymerase Beta 279NA Mutant Complexed with G in the Template Base Paired with Incoming Non-Hydrolyzable Ttp and Manganese
All present enzymatic activity of Structure of Human Dna Polymerase Beta 279NA Mutant Complexed with G in the Template Base Paired with Incoming Non-Hydrolyzable Ttp and Manganese:
2.7.7.7;
2.7.7.7;
Protein crystallography data
The structure of Structure of Human Dna Polymerase Beta 279NA Mutant Complexed with G in the Template Base Paired with Incoming Non-Hydrolyzable Ttp and Manganese, PDB code: 4z6f
was solved by
M.-C.Koag,
S.Lee,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 19.96 / 2.44 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 50.753, 79.558, 55.204, 90.00, 107.70, 90.00 |
| R / Rfree (%) | 19.5 / 24.8 |
Other elements in 4z6f:
The structure of Structure of Human Dna Polymerase Beta 279NA Mutant Complexed with G in the Template Base Paired with Incoming Non-Hydrolyzable Ttp and Manganese also contains other interesting chemical elements:
| Sodium | (Na) | 2 atoms |
Manganese Binding Sites:
The binding sites of Manganese atom in the Structure of Human Dna Polymerase Beta 279NA Mutant Complexed with G in the Template Base Paired with Incoming Non-Hydrolyzable Ttp and Manganese
(pdb code 4z6f). This binding sites where shown within
5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Structure of Human Dna Polymerase Beta 279NA Mutant Complexed with G in the Template Base Paired with Incoming Non-Hydrolyzable Ttp and Manganese, PDB code: 4z6f:
Jump to Manganese binding site number: 1; 2;
In total 2 binding sites of Manganese where determined in the Structure of Human Dna Polymerase Beta 279NA Mutant Complexed with G in the Template Base Paired with Incoming Non-Hydrolyzable Ttp and Manganese, PDB code: 4z6f:
Jump to Manganese binding site number: 1; 2;
Manganese binding site 1 out of 2 in 4z6f
Go back to
Manganese Binding Sites List in 4z6f
Manganese binding site 1 out
of 2 in the Structure of Human Dna Polymerase Beta 279NA Mutant Complexed with G in the Template Base Paired with Incoming Non-Hydrolyzable Ttp and Manganese
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 1 of Structure of Human Dna Polymerase Beta 279NA Mutant Complexed with G in the Template Base Paired with Incoming Non-Hydrolyzable Ttp and Manganese within 5.0Å range:
|
Manganese binding site 2 out of 2 in 4z6f
Go back to
Manganese Binding Sites List in 4z6f
Manganese binding site 2 out
of 2 in the Structure of Human Dna Polymerase Beta 279NA Mutant Complexed with G in the Template Base Paired with Incoming Non-Hydrolyzable Ttp and Manganese
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 2 of Structure of Human Dna Polymerase Beta 279NA Mutant Complexed with G in the Template Base Paired with Incoming Non-Hydrolyzable Ttp and Manganese within 5.0Å range:
|
Reference:
M.C.Koag,
S.Lee.
Insights Into the Effect of Minor Groove Interactions and Metal Cofactors on Mutagenic Replication By Human Dna Polymerase Beta. Biochem. J. V. 475 571 2018.
ISSN: ESSN 1470-8728
PubMed: 29301983
DOI: 10.1042/BCJ20170787
Page generated: Sat Oct 5 23:06:13 2024
ISSN: ESSN 1470-8728
PubMed: 29301983
DOI: 10.1042/BCJ20170787
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