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Manganese in PDB 4wuo: Structure of the E270A Mutant Isopropylmalate Dehydrogenase From Thermus Thermophilus in Complex with Ipm, Mn and Nadh
Enzymatic activity of Structure of the E270A Mutant Isopropylmalate Dehydrogenase From Thermus Thermophilus in Complex with Ipm, Mn and Nadh
All present enzymatic activity of Structure of the E270A Mutant Isopropylmalate Dehydrogenase From Thermus Thermophilus in Complex with Ipm, Mn and Nadh:
1.1.1.85;
1.1.1.85;
Protein crystallography data
The structure of Structure of the E270A Mutant Isopropylmalate Dehydrogenase From Thermus Thermophilus in Complex with Ipm, Mn and Nadh, PDB code: 4wuo
was solved by
A.Pallo,
E.Graczer,
J.Olah,
T.Szimler,
P.V.Konarev,
D.I.Svergun,
A.Merli,
P.Zavodszky,
M.Vas,
M.S.Weiss,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 30.00 / 2.05 |
| Space group | C 2 2 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 50.180, 143.250, 174.890, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 17 / 22.9 |
Other elements in 4wuo:
The structure of Structure of the E270A Mutant Isopropylmalate Dehydrogenase From Thermus Thermophilus in Complex with Ipm, Mn and Nadh also contains other interesting chemical elements:
| Potassium | (K) | 1 atom |
Manganese Binding Sites:
The binding sites of Manganese atom in the Structure of the E270A Mutant Isopropylmalate Dehydrogenase From Thermus Thermophilus in Complex with Ipm, Mn and Nadh
(pdb code 4wuo). This binding sites where shown within
5.0 Angstroms radius around Manganese atom.
In total 2 binding sites of Manganese where determined in the Structure of the E270A Mutant Isopropylmalate Dehydrogenase From Thermus Thermophilus in Complex with Ipm, Mn and Nadh, PDB code: 4wuo:
Jump to Manganese binding site number: 1; 2;
In total 2 binding sites of Manganese where determined in the Structure of the E270A Mutant Isopropylmalate Dehydrogenase From Thermus Thermophilus in Complex with Ipm, Mn and Nadh, PDB code: 4wuo:
Jump to Manganese binding site number: 1; 2;
Manganese binding site 1 out of 2 in 4wuo
Go back to
Manganese Binding Sites List in 4wuo
Manganese binding site 1 out
of 2 in the Structure of the E270A Mutant Isopropylmalate Dehydrogenase From Thermus Thermophilus in Complex with Ipm, Mn and Nadh
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 1 of Structure of the E270A Mutant Isopropylmalate Dehydrogenase From Thermus Thermophilus in Complex with Ipm, Mn and Nadh within 5.0Å range:
|
Manganese binding site 2 out of 2 in 4wuo
Go back to
Manganese Binding Sites List in 4wuo
Manganese binding site 2 out
of 2 in the Structure of the E270A Mutant Isopropylmalate Dehydrogenase From Thermus Thermophilus in Complex with Ipm, Mn and Nadh
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Manganese with other atoms in the Mn binding
site number 2 of Structure of the E270A Mutant Isopropylmalate Dehydrogenase From Thermus Thermophilus in Complex with Ipm, Mn and Nadh within 5.0Å range:
|
Reference:
E.Graczer,
A.Pallo,
J.Olah,
T.Szimler,
P.V.Konarev,
D.I.Svergun,
A.Merli,
P.Zavodszky,
M.S.Weiss,
M.Vas.
Essential Role of E270 in K+-Activation and Domain Closure of Thermus Thermophilus Isopropylmalate Dehydrogenase To Be Published.
Page generated: Sat Oct 5 22:53:42 2024
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