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Atomistry » Manganese » PDB 4wl8-4xwt » 4wtf | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Manganese » PDB 4wl8-4xwt » 4wtf » |
Manganese in PDB 4wtf: Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Gs-639475, MN2+ and Symmetrical Primer Template 5'- CaaaauuuEnzymatic activity of Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Gs-639475, MN2+ and Symmetrical Primer Template 5'- Caaaauuu
All present enzymatic activity of Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Gs-639475, MN2+ and Symmetrical Primer Template 5'- Caaaauuu:
2.7.7.48; Protein crystallography data
The structure of Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Gs-639475, MN2+ and Symmetrical Primer Template 5'- Caaaauuu, PDB code: 4wtf
was solved by
T.E.Edwards,
T.C.Appleby,
M.E.Mcgrath,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4wtf:
The structure of Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Gs-639475, MN2+ and Symmetrical Primer Template 5'- Caaaauuu also contains other interesting chemical elements:
Manganese Binding Sites:
The binding sites of Manganese atom in the Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Gs-639475, MN2+ and Symmetrical Primer Template 5'- Caaaauuu
(pdb code 4wtf). This binding sites where shown within
5.0 Angstroms radius around Manganese atom.
In total 3 binding sites of Manganese where determined in the Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Gs-639475, MN2+ and Symmetrical Primer Template 5'- Caaaauuu, PDB code: 4wtf: Jump to Manganese binding site number: 1; 2; 3; Manganese binding site 1 out of 3 in 4wtfGo back to Manganese Binding Sites List in 4wtf
Manganese binding site 1 out
of 3 in the Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Gs-639475, MN2+ and Symmetrical Primer Template 5'- Caaaauuu
Mono view Stereo pair view
Manganese binding site 2 out of 3 in 4wtfGo back to Manganese Binding Sites List in 4wtf
Manganese binding site 2 out
of 3 in the Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Gs-639475, MN2+ and Symmetrical Primer Template 5'- Caaaauuu
Mono view Stereo pair view
Manganese binding site 3 out of 3 in 4wtfGo back to Manganese Binding Sites List in 4wtf
Manganese binding site 3 out
of 3 in the Crystal Structure of Hcv NS5B Genotype 2A Jfh-1 Isolate with S15G E86Q E87Q C223H V321I Mutations and DELTA8 Beta Hairpin Loop Deletion in Complex with Gs-639475, MN2+ and Symmetrical Primer Template 5'- Caaaauuu
Mono view Stereo pair view
Reference:
T.C.Appleby,
J.Perry,
E.Murakami,
O.Barauskas,
J.Feng,
A.Cho,
D.Fox Iii,
D.R.Wetmore,
M.E.Mcgrath,
A.S.Ray,
M.J.Sofia,
S.Swaminathan,
T.E.Edwards.
Structural Basis For Rna Replication By the Hepatitis C Virus Polymerase To Be Published.
Page generated: Tue Dec 15 04:33:03 2020
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